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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Prochlorococcus marinus (strain AS9601)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciPMAR146891:GH90-1720-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:A9601_16891
OrganismiProchlorococcus marinus (strain AS9601)
Taxonomic identifieri146891 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
Proteomesi
  • UP000002590 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10971097DNA-directed RNA polymerase subunit betaPRO_0000300369Add
BLAST

Proteomic databases

PRIDEiA2BT61.

Interactioni

Subunit structurei

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi146891.A9601_16891.

Structurei

3D structure databases

ProteinModelPortaliA2BT61.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QIH. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiPOG091H01MI.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2BT61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSALQVAK TATYLPDLVE VQRASFKWFL EKGLIEELQN FSPISDYTGK
60 70 80 90 100
LELHFIGEEY RLKRPRHDVE EAKRRDATFA SQMYVTCRLI NKETGEIKEQ
110 120 130 140 150
EVFIGELPLM TERGTFIING AERVIVNQIV RSPGVYFKDE LDKNGRRTYN
160 170 180 190 200
ANVIPNRGAW LKFETDKNNL LYVRVDKTRK INAHVLMRAM GLSDNDVVDK
210 220 230 240 250
LRHPEFYQNS IDSANDEGIN SEDQALLELY KKLRPGEPPS VSGGQQLLNS
260 270 280 290 300
RFFDPKRYDL GRVGRYKINK KLRLTVPDDV RTLTHEDVLS TIDYLINLEL
310 320 330 340 350
DIGGASLDDI DHLGNRRVRS VGELLQNQVR VGLNRLERII KERMTVGETD
360 370 380 390 400
SLTPAQLVNP KPLVAAIKEF FGSSQLSQFM DQTNPLAELT HKRRISALGP
410 420 430 440 450
GGLTRERAGF AVRDIHPSHY GRLCPIETPE GPNAGLINSL ATHARVNEYG
460 470 480 490 500
FIETPFWEVK NGKVNKEGNP VYLSADLEDE CRVAPGDVAT DKDGNIIADL
510 520 530 540 550
IPVRYRQDFE KVPPHQVDYV QLSPVQVISV ATSLIPFLEH DDANRALMGS
560 570 580 590 600
NMQRQAVPLL RPERPLVGTG LESQVARDSG MVPITKVNGT VSYVDANEIV
610 620 630 640 650
VKDDHGNEHF HYLQKYQRSN QDTCLNQRPI VKIGDKVISG QVLADGSACE
660 670 680 690 700
GGEIALGQNV LIAYMPWEGY NYEDAILVSE RMVTDDLYTS VHIEKYEIEA
710 720 730 740 750
RQTKLGPEEI TREIPNISEE SLNNLDEMGI IRIGAFVESG DILVGKVTPK
760 770 780 790 800
GESDQPPEEK LLRAIFGEKA RDVRDNSLRV PKTEKGRVLD VRIYTREQGD
810 820 830 840 850
ELPPGANMVV RVYVAQRRKI QVGDKMAGRH GNKGIISRIL PREDMPYLPD
860 870 880 890 900
GTPVDIVLNP LGVPSRMNVG QVFELLMGWA AANLNCRVKV VPFDEMYGAE
910 920 930 940 950
KSHQTVQAFL EEASKQPGKA WVYNPEDPGK LLLKDGRTGE PFDQPVAVGY
960 970 980 990 1000
SHFLKLVHLV DDKIHARSTG PYSLVTQQPL GGKAQQGGQR LGEMEVWALE
1010 1020 1030 1040 1050
AYGAAYTLQE LLTVKSDDMQ GRNEALNAIV KGKPIPRPGT PESFKVLMRE
1060 1070 1080 1090
LQSLGLDIGV YTDEGKEVDL MQDINPRRNT PSRPTYESLG TSEYEED
Length:1,097
Mass (Da):122,972
Last modified:February 20, 2007 - v1
Checksum:i95AABBBD25D9C50B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM70972.1.
RefSeqiWP_011819100.1. NC_008816.1.

Genome annotation databases

EnsemblBacteriaiABM70972; ABM70972; A9601_16891.
KEGGipmb:A9601_16891.
PATRICi22984913. VBIProMar75723_1700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM70972.1.
RefSeqiWP_011819100.1. NC_008816.1.

3D structure databases

ProteinModelPortaliA2BT61.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi146891.A9601_16891.

Proteomic databases

PRIDEiA2BT61.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM70972; ABM70972; A9601_16891.
KEGGipmb:A9601_16891.
PATRICi22984913. VBIProMar75723_1700.

Phylogenomic databases

eggNOGiENOG4107QIH. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiPOG091H01MI.

Enzyme and pathway databases

BioCyciPMAR146891:GH90-1720-MONOMER.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB_PROMS
AccessioniPrimary (citable) accession number: A2BT61
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 20, 2007
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.