A2BSJ2 (SURE_PROMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	A9601_14701

Organism

Prochlorococcus marinus (strain AS9601) [Complete proteome] [HAMAP]

Taxonomic identifier

146891 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	5'-nucleotidase surE HAMAP MF_00060		PRO_1000007765
Sites
	Metal binding	11	1	Divalent metal cation By similarity
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	43	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A2BSJ2 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 5C724E7AA6988762	FASTA	269	29,437
	10 20 30 40 50 60 MKPLNILISN DDGVFAAGIR ALAKSAQKRG HKVKVVCPDQ ERSATGHGLT LQSPLRVEKA 70 80 90 100 110 120 DELFGEGIEA WGCSGTPADC VKLALSELLD NKPDLILSGI NHGPNLGTDI FCSGTVAAAM 130 140 150 160 170 180 EGTLENVPSM AISVASFKWK NFEAAGEIAM NIAEQAINDS WPASLLLNLN IPPCDKSKIK 190 200 210 220 230 240 ELSWTRLSVR KYKNQFSKRE DPRGDDYYWL AGEVVLDLKS KGYGPKNWPS DVSQIQDNKI 250 260 SLTPVEPDLF WRGDLENLPK INNSFINPS

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AS9601.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000551 Genomic DNA. Translation: ABM70753.1.
RefSeq	YP_001009860.1. NC_008816.1.
3D structure databases
ProteinModelPortal	A2BSJ2.
ModBase	Search...
Protein-protein interaction databases
STRING	A2BSJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4718191.
GenomeReviews	Gene locus A9601_14701 in contig CP000551_GR.
KEGG	pmb:A9601_14701.
PATRIC	22984459. VBIProMar75723_1477.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	NGFYYVN.
PhylomeDB	A2BSJ2.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	PMAR146891:A9601_14701-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_PROMS

Accession

Primary (citable) accession number: A2BSJ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program