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A2BRB1 (A2BRB1_PROMS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102
Ordered Locus Names:A9601_10381
OrganismProchlorococcus marinus (strain AS9601) [Complete proteome] [HAMAP] EMBL ABM70322.1
Taxonomic identifier146891 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102

Subcellular location

Cytoplasm By similarity HAMAP MF_00102.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A2BRB1 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 5EA7BDF49DA86AF3

FASTA28230,676
        10         20         30         40         50         60 
MIKNSTKPIP VLVSGALGRM GSEVVNTVLN STDCELVAAI DINEKNNGSN ISELLKVKNC 

        70         80         90        100        110        120 
DVFVSNDFEG TLCSVSQDFR NEKIKPVLVD FTHPDSVYEN TRSAIAYGVS PVVGTTGLSP 

       130        140        150        160        170        180 
SQIQDLSVFA QKASVGCAII PNFSVGMVLL QQAASVAARF YDNIELIEMH HNQKADSPSG 

       190        200        210        220        230        240 
TCIKTAEMIE EYPKKFNQNL VKESESLKGV RGGLRDSGIN IHSVRLPGLL AHQLVIMGSP 

       250        260        270        280 
GETYTIKHDT IDRKAYMPGV LQAIKKIGNY ETLIYGLEKL IF

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000551 Genomic DNA. Translation: ABM70322.1.
RefSeqYP_001009429.1. NC_008816.1.

3D structure databases

ProteinModelPortalA2BRB1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2BRB1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4717749.
GenomeReviewsGene locus A9601_10381 in contig CP000551_GR.
KEGGpmb:A9601_10381.
PATRIC22983579. VBIProMar75723_1045.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0289.
HOGENOMHBG594002.
OMAPESENTH.
PhylomeDBA2BRB1.
ProtClustDBPRK00048.

Enzyme and pathway databases

BioCycPMAR146891:A9601_10381-MONOMER.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2BRB1_PROMS
AccessionPrimary (citable) accession number: A2BRB1
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info