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A2BQ65 (GLGB_PROMS) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:A9601_06401
OrganismProchlorococcus marinus (strain AS9601) [Complete proteome] [HAMAP]
Taxonomic identifier146891 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length754 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7547541,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_1000044992

Sites

Active site4311Nucleophile By similarity
Active site4841Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A2BQ65 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 2995D16898114DDD

FASTA75488,297
        10         20         30         40         50         60 
MIETIQADWI KSEAINLENC CNDNPLKILG PHFYEEQWVI RVWMPEADEV KINFKNNTYK 

        70         80         90        100        110        120 
AESINHKWLF EAILPENPNH NYEINILRGG VTHTQHDPWS YREEWMGEVD RHLFAEGNHH 

       130        140        150        160        170        180 
HIWEKMGAHL IEEKNQKGVM FCIWAPNAKS ISIIGDINSW DGRHHPMQKR LGGIWELFMP 

       190        200        210        220        230        240 
SMQEGDTYKY EIRTQQGHIY EKADPYGFLH EIRPQNGSIV SKLKNFNWND SSWISNRDSS 

       250        260        270        280        290        300 
SQINKPISVY EMHLGSWLHE STDNKYLENN GDPRDPVPAA DLKPGTRLLT YPELTKKLIP 

       310        320        330        340        350        360 
YVKERGFTHI ELMPISEHPF DGSWGYQVTG WYAPTSRFGT PNEFREFVNK CHEEGIGVIL 

       370        380        390        400        410        420 
DWVPGHFPKD KHGLAFFDGC HLYEHGDSRI GEHKEWGTLI FNYSRNEVRN FLVANLVYWF 

       430        440        450        460        470        480 
EEFHIDGIRV DAVASMLYRD YLRPDGEWIP NENGGNENIE AVKFLQQANH VLFQHFPGAL 

       490        500        510        520        530        540 
SIAEESTTWP MVTKPTDMGG LGFNLKWNMG WMHDMLDYFE IDPWFRQFHQ NSVTFSITYN 

       550        560        570        580        590        600 
YTENFMLALS HDEVVHGKSH LLHKMPGDDW KKYANTRALL TYMWTHPGKK TIFMGMEFGQ 

       610        620        630        640        650        660 
RQEWNVWDDL QWELLEFEPH KGIRNLIDDL NVLYKNEPAL WKNDFDPYGF QWIDCNDKSN 

       670        680        690        700        710        720 
SVISFMRREN DTNEWLVVVA NFTPNTHESY KVGVPMEGFY REIFNSDGSR YGGSNKGNLG 

       730        740        750 
GKETINYNIH DYQNALELAL PPLSVSIFKH QSKK 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AS9601.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000551 Genomic DNA. Translation: ABM69926.1.
RefSeqYP_001009033.1. NC_008816.1.

3D structure databases

ProteinModelPortalA2BQ65.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING146891.A9601_06401.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM69926; ABM69926; A9601_06401.
GeneID4717341.
KEGGpmb:A9601_06401.
PATRIC22982760. VBIProMar75723_0640.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycPMAR146891:GH90-658-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_PROMS
AccessionPrimary (citable) accession number: A2BQ65
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: June 11, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries