A2BPP7 (MQO_PROMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	A9601_04701

Organism

Prochlorococcus marinus (strain AS9601) [Complete proteome] [HAMAP]

Taxonomic identifier

146891 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 498	498	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325505

Sequences

	Sequence		Length	Mass (Da)
	A2BPP7 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 41EE6FDB046DB448	FASTA	498	55,590
	10 20 30 40 50 60 MTSSKNPTND NSYFDAVLVG AGIMSSTLAL LISEVLPDIK FLILEKLNAP GSESTGAFNN 70 80 90 100 110 120 AGTGHAANCE LNYTPLDEKG NLIIDKALSI NRSFETSMSL WASLYEAGKI DIKKFLKFIP 130 140 150 160 170 180 HISFVSGQDN ISFLKKRFQK MTENPEFIDM EFSTSFDEIS SWAPLITKDR NPSTQIAATR 190 200 210 220 230 240 IDRGTDINFE ALTKEYLSLV SLNKNVEIRY KTELVDLKKI DKKQWELEIS SEGRKTSIRS 250 260 270 280 290 300 GYVFLGAGGK TINYLQKSKI PEAKSYGGFP VSGKWLICEK KDLTEKHNSK VYGKADIGSP 310 320 330 340 350 360 PMSVPHLDTR WIDNKKLLLY GPFAGFTTKF LKQSSYFDLF SSIKKNNIFS MLDVGFKNND 370 380 390 400 410 420 LINYLISQSL KNHNSRVENL KNMMPSANPS DWYLKNAGQR VQIIKKTEGG GSLKFGTEIV 430 440 450 460 470 480 NSSDGSLSAL LGASPGASTA VSIMVEVLEK SVLFLNDKHN LQKKINDLIY PELSVSENYS 490 TFIKEIKKRN NSIFGFHP

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AS9601.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000551 Genomic DNA. Translation: ABM69758.1.
RefSeq	YP_001008865.1. NC_008816.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A2BPP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4717168.
GenomeReviews	Gene locus A9601_04701 in contig CP000551_GR.
KEGG	pmb:A9601_04701.
PATRIC	22982409. VBIProMar75723_0468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	KKWVPLM.
PhylomeDB	A2BPP7.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	PMAR146891:A9601_04701-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MQO_PROMS

Accession

Primary (citable) accession number: A2BPP7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program