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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain AS9601)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciPMAR146891:GH90-486-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:A9601_04701
OrganismiProchlorococcus marinus (strain AS9601)
Taxonomic identifieri146891 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
Proteomesi
  • UP000002590 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 498498Probable malate:quinone oxidoreductasePRO_0000325505Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi146891.A9601_04701.

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

A2BPP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSKNPTND NSYFDAVLVG AGIMSSTLAL LISEVLPDIK FLILEKLNAP
60 70 80 90 100
GSESTGAFNN AGTGHAANCE LNYTPLDEKG NLIIDKALSI NRSFETSMSL
110 120 130 140 150
WASLYEAGKI DIKKFLKFIP HISFVSGQDN ISFLKKRFQK MTENPEFIDM
160 170 180 190 200
EFSTSFDEIS SWAPLITKDR NPSTQIAATR IDRGTDINFE ALTKEYLSLV
210 220 230 240 250
SLNKNVEIRY KTELVDLKKI DKKQWELEIS SEGRKTSIRS GYVFLGAGGK
260 270 280 290 300
TINYLQKSKI PEAKSYGGFP VSGKWLICEK KDLTEKHNSK VYGKADIGSP
310 320 330 340 350
PMSVPHLDTR WIDNKKLLLY GPFAGFTTKF LKQSSYFDLF SSIKKNNIFS
360 370 380 390 400
MLDVGFKNND LINYLISQSL KNHNSRVENL KNMMPSANPS DWYLKNAGQR
410 420 430 440 450
VQIIKKTEGG GSLKFGTEIV NSSDGSLSAL LGASPGASTA VSIMVEVLEK
460 470 480 490
SVLFLNDKHN LQKKINDLIY PELSVSENYS TFIKEIKKRN NSIFGFHP
Length:498
Mass (Da):55,590
Last modified:February 20, 2007 - v1
Checksum:i41EE6FDB046DB448
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM69758.1.
RefSeqiWP_011817926.1. NC_008816.1.

Genome annotation databases

EnsemblBacteriaiABM69758; ABM69758; A9601_04701.
KEGGipmb:A9601_04701.
PATRICi22982409. VBIProMar75723_0468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM69758.1.
RefSeqiWP_011817926.1. NC_008816.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi146891.A9601_04701.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM69758; ABM69758; A9601_04701.
KEGGipmb:A9601_04701.
PATRICi22982409. VBIProMar75723_0468.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciPMAR146891:GH90-486-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AS9601.

Entry informationi

Entry nameiMQO_PROMS
AccessioniPrimary (citable) accession number: A2BPP7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: February 20, 2007
Last modified: November 11, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.