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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Prochlorococcus marinus (strain AS9601)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pykF)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei40SubstrateUniRule annotation1
Binding sitei122SubstrateUniRule annotation1
Binding sitei155SubstrateUniRule annotation1
Binding sitei206ATPUniRule annotation1
Binding sitei297ATP; via carbonyl oxygenUniRule annotation1
Binding sitei328ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi358 – 361ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR146891:G1G7X-209-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:A9601_02131
OrganismiProchlorococcus marinus (strain AS9601)
Taxonomic identifieri146891 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002590 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000580311 – 402Phosphoglycerate kinaseAdd BLAST402

Proteomic databases

PRIDEiA2BNZ0

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi146891.A9601_02131

Structurei

3D structure databases

ProteinModelPortaliA2BNZ0
SMRiA2BNZ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni24 – 26Substrate bindingUniRule annotation3
Regioni63 – 66Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227108
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A2BNZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLSLSSLD KTHLEGKKVL VRVDFNVPLN EDGQITDDTR IRAAIPTIEY
60 70 80 90 100
LINHSAKVIL AAHFGRPKGQ VNEKMRLTPV AARLSELLGQ NVALTNSCIG
110 120 130 140 150
DEAVAQSNSL SNGDVLLLEN VRFFGEEEKN DLEFAEKLAS HADMYVNDAF
160 170 180 190 200
GAAHRAHAST QGVTNYLSPS VAGFLLEKEL KYLQGAVDSP NRPLAAIVGG
210 220 230 240 250
SKVSSKIGVL DSLLDKCDKI MIGGGMIFTF YKARGLDVGK SLVEEDKLEL
260 270 280 290 300
AKDLEAKAKA KGVELLLPTD VVLADEFSPD ANSKISQIDA ISGNWMGLDI
310 320 330 340 350
GPDSIKVFQN ALAECKTIIW NGPMGVFEFD KFADGTNAIA TTLADLSAFS
360 370 380 390 400
EVCTIIGGGD SVAAVEKAGL AEKMSHISTG GGASLELLEG KTLPGVAALN

DA
Length:402
Mass (Da):42,649
Last modified:February 20, 2007 - v1
Checksum:iF87BDE42E12C4028
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA Translation: ABM69501.1
RefSeqiWP_011817688.1, NC_008816.1

Genome annotation databases

EnsemblBacteriaiABM69501; ABM69501; A9601_02131
GeneIDi4716897
KEGGipmb:A9601_02131

Similar proteinsi

Entry informationi

Entry nameiPGK_PROMS
AccessioniPrimary (citable) accession number: A2BNZ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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