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Protein

Nucleoside-triphosphatase THEP1

Gene

Hbut_0898

Organism
Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.UniRule annotation

Catalytic activityi

NTP + H2O = NDP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 168ATPUniRule annotation
Nucleotide bindingi100 – 1078ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHBUT415426:GC56-898-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside-triphosphatase THEP1UniRule annotation (EC:3.6.1.15UniRule annotation)
Short name:
NTPase THEP1UniRule annotation
Alternative name(s):
Nucleoside triphosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:Hbut_0898
OrganismiHyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Taxonomic identifieri415426 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesPyrodictiaceaeHyperthermus
Proteomesi
  • UP000002593 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Nucleoside-triphosphatase THEP1PRO_0000360021Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi415426.Hbut_0898.

Structurei

3D structure databases

ProteinModelPortaliA2BL86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEP1 NTPase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiRILYITG.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A2BL86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSYVVVTGR PGVGKTTLFW KVVRKLMDEG VVVKGFYCPE VRGQQGYRIG
60 70 80 90 100
FKIVLLDGSG EAWLARREGC NGPRVGRYYT CPEAETIASR VLGELGKADL
110 120 130 140 150
IAIDEIGPME LRLAGVRRTI YRVLDSGKPG LFVVHERLSD PYILARLKPS
160 170 180
GVWFHVTIEN RDVLPEKVYE AVKQAVARSK GVGELSL
Length:187
Mass (Da):20,773
Last modified:February 20, 2007 - v1
Checksum:i367CFACFEA7B0FC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000493 Genomic DNA. Translation: ABM80747.1.
RefSeqiWP_011822065.1. NC_008818.1.

Genome annotation databases

EnsemblBacteriaiABM80747; ABM80747; Hbut_0898.
GeneIDi4782722.
KEGGihbu:Hbut_0898.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000493 Genomic DNA. Translation: ABM80747.1.
RefSeqiWP_011822065.1. NC_008818.1.

3D structure databases

ProteinModelPortaliA2BL86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi415426.Hbut_0898.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM80747; ABM80747; Hbut_0898.
GeneIDi4782722.
KEGGihbu:Hbut_0898.

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiRILYITG.

Enzyme and pathway databases

BioCyciHBUT415426:GC56-898-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNTPTH_HYPBU
AccessioniPrimary (citable) accession number: A2BL86
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: February 20, 2007
Last modified: December 9, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.