A2BL20 (A2BL20_HYPBU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Ordered Locus Names:

Hbut_0829

Organism

Hyperthermus butylicus (strain DSM 5456 / JCM 9403)

Taxonomic identifier

415426 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Pyrodictiaceae › Hyperthermus

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 Methyltransferase EMBL ABM80681.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2BL20 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 075A7127A3039254	FASTA	378	41,757
	10 20 30 40 50 60 MTGVKVPLYD VHRELGASLG EFAGWLVPID YGSIVEEHVA VRKTVGFFDL SHMARIIVSG 70 80 90 100 110 120 PDAGKLLDKL VPRYLESEPG TMLGPTAFLN ENAGFVDDVM LYNLGGNQWM IVANAVNREK 130 140 150 160 170 180 VLGWLNDWLS RLGFTASVED KTLELAMFAV QGPKAAELME RLGAPREVLE LKLLRFRLNV 190 200 210 220 230 240 ELSEAKARAF LVSRSGWTGE DGFEIIAPVG EAEKILRKAA EIVRELGGRL CGLGARDSLR 250 260 270 280 290 300 MEMGFVLYGH EIDEETTPVD ARYWWVYQPG PKEDCVGCKA LREALRRGAV KVRVGIRLSK 310 320 330 340 350 360 KARIVPRQGD KIYVEGVEVG HVTSGAYSPV LGRSIAQAYI KPSHALMGLT VEVERRGKRY 370 QGKIVDFPLV KPTSSPPL

References

[1]

"The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C." Bruegger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M., She Q., Garrett R.A., Klenk H.-P. Archaea 2:127-135(2007) [PubMed: 17350933] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 5456 / JCM 9403.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000493 Genomic DNA. Translation: ABM80681.1.
RefSeq	YP_001013026.1. NC_008818.1.
3D structure databases
ProteinModelPortal	A2BL20.
ModBase	Search...
Protein-protein interaction databases
STRING	A2BL20.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4781869.
GenomeReviews	Gene locus Hbut_0829 in contig CP000493_GR.
KEGG	hbu:Hbut_0829.
Phylogenomic databases
eggNOG	arNOG06551.
HOGENOM	HBG299834.
OMA	RITRCGY.
PhylomeDB	A2BL20.
ProtClustDB	PRK00389.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2BL20_HYPBU

Accession

Primary (citable) accession number: A2BL20

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)