ID   A2BK89_HYPBU            Unreviewed;       336 AA.
AC   A2BK89;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Geranylgeranyl pyrophosphate synthetase {ECO:0000313|EMBL:ABM80400.1};
DE            EC=2.5.1.1 {ECO:0000313|EMBL:ABM80400.1};
GN   OrderedLocusNames=Hbut_0540 {ECO:0000313|EMBL:ABM80400.1};
OS   Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5).
OC   Archaea; Thermoproteota; Thermoprotei; Desulfurococcales; Pyrodictiaceae;
OC   Hyperthermus.
OX   NCBI_TaxID=415426 {ECO:0000313|EMBL:ABM80400.1, ECO:0000313|Proteomes:UP000002593};
RN   [1] {ECO:0000313|EMBL:ABM80400.1, ECO:0000313|Proteomes:UP000002593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5456 / JCM 9403 / PLM1-5
RC   {ECO:0000313|Proteomes:UP000002593};
RX   PubMed=17350933;
RA   Brugger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M.,
RA   She Q., Garrett R.A., Klenk H.P.;
RT   "The genome of Hyperthermus butylicus: a sulfur-reducing, peptide
RT   fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
RL   Archaea 2:127-135(2007).
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR   EMBL; CP000493; ABM80400.1; -; Genomic_DNA.
DR   RefSeq; WP_011821718.1; NC_008818.1.
DR   AlphaFoldDB; A2BK89; -.
DR   STRING; 415426.Hbut_0540; -.
DR   EnsemblBacteria; ABM80400; ABM80400; Hbut_0540.
DR   GeneID; 4782205; -.
DR   KEGG; hbu:Hbut_0540; -.
DR   eggNOG; arCOG01726; Archaea.
DR   HOGENOM; CLU_014015_2_1_2; -.
DR   OrthoDB; 26738at2157; -.
DR   Proteomes; UP000002593; Chromosome.
DR   GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002593};
KW   Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:ABM80400.1}.
SQ   SEQUENCE   336 AA;  37010 MW;  5EE060B4FEB97C96 CRC64;
     MTGQLPESVV AYLKRVASLV DGYIYAKVKG EPKEVYDAGL HLIRAGGKRL RPAIVVAIAE
     ALGEPAERAL PFAAAVELVH NFTLIHDDIM DRDEFRRGVP TVHKVWGEPL AITAGDLLFA
     KAFETLTDAL DKGIPPDRVA RATRVLSRAS AVIAEGQAMD LMFEEEDEVS IDEYLIMIYK
     KTGALFEASA VLGGLVATGD DATLEKLAEF GKNLGIAFQI RDDILGIVGK EEELGKPVYS
     DIREGKKTLP IIYALRNLED EDREKLVMVL GNREASREEL EQAAKLVVAS GAIDYAESKA
     REYIDRALEA LRGAVPENNY RRILEELAKF VATRTW
//