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Protein
Submitted name:

Hydroxymethylbilane synthase a

Gene

hmbsa

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-189451 Heme biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxymethylbilane synthase aImported
Gene namesi
Name:hmbsaImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-040426-1375 hmbsa

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiA2BFN6
PeptideAtlasiA2BFN6

Expressioni

Gene expression databases

BgeeiENSDARG00000008840
ExpressionAtlasiA2BFN6 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000023322

Structurei

3D structure databases

ProteinModelPortaliA2BFN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 230Porphobil_deamInterPro annotationAdd BLAST212
Domaini243 – 296Porphobil_deamCInterPro annotationAdd BLAST54

Phylogenomic databases

eggNOGiKOG2892 Eukaryota
COG0181 LUCA
GeneTreeiENSGT00390000009083
HOGENOMiHOG000228587
HOVERGENiHBG000967
InParanoidiA2BFN6
OMAiCQVPIGV
TreeFamiTF105389

Family and domain databases

Gene3Di3.30.160.40, 1 hit
HAMAPiMF_00260 Porphobil_deam, 1 hit
InterProiView protein in InterPro
IPR000860 HemC
IPR022419 Porphobilin_deaminase_cofac_BS
IPR022417 Porphobilin_deaminase_N
IPR022418 Porphobilinogen_deaminase_C
IPR036803 Porphobilinogen_deaminase_C_sf
PANTHERiPTHR11557 PTHR11557, 1 hit
PfamiView protein in Pfam
PF01379 Porphobil_deam, 1 hit
PF03900 Porphobil_deamC, 1 hit
PIRSFiPIRSF001438 4pyrrol_synth_OHMeBilane_synth, 1 hit
PRINTSiPR00151 PORPHBDMNASE
SUPFAMiSSF54782 SSF54782, 2 hits
TIGRFAMsiTIGR00212 hemC, 1 hit
PROSITEiView protein in PROSITE
PS00533 PORPHOBILINOGEN_DEAM, 1 hit

Sequencei

Sequence statusi: Complete.

A2BFN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGPFKYIRE GNGKASRVIR MGTRKSQLAR IQTDSVAGTL KQLYPDVHLE
60 70 80 90 100
IVAMSTIGDK ILDTALSKIG EKSLFTKELE NALERNEVDI VVHSLKDLPT
110 120 130 140 150
SLPPGFTIGA ILERENPHDA VVLHPKNAGL TLDSLPEKSV IGTSSLRRAA
160 170 180 190 200
QLKKRFPQLE FENIRGNLNT RLKKLDEKDD YAAIILAAAG LKRMGWESRI
210 220 230 240 250
SQVLGPEDCM YAVGQGALAV EVRAQDKDIL EMVSVLHHPD TVLRCISERA
260 270 280 290 300
FLKQLEGGCS VPVAVHTEVK GSMLYLTGAV YSLDGADCLK DTMQTCVELD
310 320 330 340 350
NKVNESTQRS ANVGVTACNI SSSALEAAEK LGLDLANVLL NKGAKDILTT

ARKLNDAR
Length:358
Mass (Da):39,000
Last modified:February 20, 2007 - v1
Checksum:i96E783508894EE80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294169 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000013431; ENSDARP00000023322; ENSDARG00000008840

Similar proteinsi

Entry informationi

Entry nameiA2BFN6_DANRE
AccessioniPrimary (citable) accession number: A2BFN6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health