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Protein
Submitted name:

Forkhead box protein D3

Gene

Foxd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • anatomical structure morphogenesis Source: GO_Central
  • embryonic placenta development Source: MGI
  • negative regulation of transcription from RNA polymerase II promoter Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • transcription, DNA-templated Source: MGI
  • transcription from RNA polymerase II promoter Source: GOC
  • trophectodermal cell differentiation Source: MGI
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein D3Imported
Gene namesi
Name:Foxd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1347473. Foxd3.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

  • nuclear chromatin Source: MGI
  • nucleus Source: GO_Central
  • transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiA2BDY3.

Expressioni

Gene expression databases

BgeeiA2BDY3.
ExpressionAtlasiA2BDY3. baseline and differential.
GenevisibleiA2BDY3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084541.

Structurei

3D structure databases

ProteinModelPortaliA2BDY3.
SMRiA2BDY3. Positions 130-226.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118904.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.
KOiK09397.
OMAiALQYPYA.
OrthoDBiEOG7C8GHD.
PhylomeDBiA2BDY3.
TreeFamiTF316127.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2BDY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP
60 70 80 90 100
PDLRLDEADE GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG
110 120 130 140 150
EDAVTGGGGP GAGSGATGGL TPNKPKNSLV KPPYSYIALI TMAILQSPQK
160 170 180 190 200
KLTLSGICEF ISNRFPYYRE KFPAWQNSIR HNLSLNDCFV KIPREPGNPG
210 220 230 240 250
KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA LMMQSFGAYS
260 270 280 290 300
LAAAAGAGPY GRPYGLHPAA AAGAYSHPAA AAAAAAAAAL QYPYALPPVA
310 320 330 340 350
PVLPPAVPLL PSGELGRKAA AFGSQLGPSL QLQLNTLGAA AAAAGTAGAA
360 370 380 390 400
GTTSLIKSEP SARPSFSIEN IIGAGSAAPG GSAGGGGSGG GAGGGGGSGG
410 420 430 440 450
GGGAQSFLRP PGTVQSAALM ATHQPLSLSR TTATIAPILS VPLSGQFLQP
460
AASAAAAAAA AVQAKWPAQ
Length:469
Mass (Da):46,818
Last modified:February 20, 2007 - v1
Checksum:i95E71211C79FAB03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqiNP_034555.3. NM_010425.3.
UniGeneiMm.4758.

Genome annotation databases

EnsembliENSMUST00000087285; ENSMUSP00000084541; ENSMUSG00000067261.
GeneIDi15221.
KEGGimmu:15221.
UCSCiuc008tuv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqiNP_034555.3. NM_010425.3.
UniGeneiMm.4758.

3D structure databases

ProteinModelPortaliA2BDY3.
SMRiA2BDY3. Positions 130-226.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084541.

Proteomic databases

PRIDEiA2BDY3.

Protocols and materials databases

DNASUi15221.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000087285; ENSMUSP00000084541; ENSMUSG00000067261.
GeneIDi15221.
KEGGimmu:15221.
UCSCiuc008tuv.1. mouse.

Organism-specific databases

CTDi27022.
MGIiMGI:1347473. Foxd3.

Phylogenomic databases

GeneTreeiENSGT00760000118904.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.
KOiK09397.
OMAiALQYPYA.
OrthoDBiEOG7C8GHD.
PhylomeDBiA2BDY3.
TreeFamiTF316127.

Miscellaneous databases

NextBioi287807.
SOURCEiSearch...

Gene expression databases

BgeeiA2BDY3.
ExpressionAtlasiA2BDY3. baseline and differential.
GenevisibleiA2BDY3. MM.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2BDY3_MOUSE
AccessioniPrimary (citable) accession number: A2BDY3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: June 24, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.