SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A2BDY3

- A2BDY3_MOUSE

UniProt

A2BDY3 - A2BDY3_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Forkhead box protein D3
Gene
Foxd3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. DNA binding, bending Source: RefGenome
  2. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: RefGenome
  3. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
  4. RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: Ensembl
  5. double-stranded DNA binding Source: RefGenome
  6. transcription factor binding Source: RefGenome
  7. transcription regulatory region DNA binding Source: MGI
Complete GO annotation...

GO - Biological processi

  1. axon extension involved in axon guidance Source: RefGenome
  2. branching involved in ureteric bud morphogenesis Source: RefGenome
  3. cartilage development Source: RefGenome
  4. embryonic placenta development Source: MGI
  5. enteric nervous system development Source: RefGenome
  6. iridophore differentiation Source: RefGenome
  7. kidney development Source: RefGenome
  8. lateral line nerve glial cell development Source: RefGenome
  9. melanocyte differentiation Source: RefGenome
  10. neural crest cell migration Source: RefGenome
  11. pattern specification process Source: RefGenome
  12. peripheral nervous system development Source: RefGenome
  13. positive regulation of transcription from RNA polymerase II promoter Source: RefGenome
  14. regulation of sequence-specific DNA binding transcription factor activity Source: RefGenome
  15. sympathetic nervous system development Source: RefGenome
  16. transcription from RNA polymerase II promoter Source: GOC
  17. transcription, DNA-templated Source: MGI
  18. trophectodermal cell differentiation Source: MGI
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotations

Keywords - Ligandi

DNA-bindingSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein D3Imported
Gene namesi
Name:Foxd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:1347473. Foxd3.

Subcellular locationi

Nucleus By similarity SAAS annotations

GO - Cellular componenti

  1. nuclear chromatin Source: Ensembl
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

PTM / Processingi

Proteomic databases

PRIDEiA2BDY3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084541.

Structurei

3D structure databases

ProteinModelPortaliA2BDY3.
SMRiA2BDY3. Positions 130-226.

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000115067.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.
InParanoidiA2BDY3.
KOiK09397.
OMAiALQYPYA.
OrthoDBiEOG7C8GHD.
PhylomeDBiA2BDY3.
TreeFamiTF316127.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2BDY3-1 [UniParc]FASTAAdd to Basket

« Hide

MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP    50
PDLRLDEADE GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG 100
EDAVTGGGGP GAGSGATGGL TPNKPKNSLV KPPYSYIALI TMAILQSPQK 150
KLTLSGICEF ISNRFPYYRE KFPAWQNSIR HNLSLNDCFV KIPREPGNPG 200
KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA LMMQSFGAYS 250
LAAAAGAGPY GRPYGLHPAA AAGAYSHPAA AAAAAAAAAL QYPYALPPVA 300
PVLPPAVPLL PSGELGRKAA AFGSQLGPSL QLQLNTLGAA AAAAGTAGAA 350
GTTSLIKSEP SARPSFSIEN IIGAGSAAPG GSAGGGGSGG GAGGGGGSGG 400
GGGAQSFLRP PGTVQSAALM ATHQPLSLSR TTATIAPILS VPLSGQFLQP 450
AASAAAAAAA AVQAKWPAQ 469
Length:469
Mass (Da):46,818
Last modified:February 20, 2007 - v1
Checksum:i95E71211C79FAB03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqiNP_034555.3. NM_010425.3.
UniGeneiMm.4758.

Genome annotation databases

EnsembliENSMUST00000087285; ENSMUSP00000084541; ENSMUSG00000067261.
GeneIDi15221.
KEGGimmu:15221.
UCSCiuc008tuv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqi NP_034555.3. NM_010425.3.
UniGenei Mm.4758.

3D structure databases

ProteinModelPortali A2BDY3.
SMRi A2BDY3. Positions 130-226.
ModBasei Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000084541.

Proteomic databases

PRIDEi A2BDY3.

Protocols and materials databases

DNASUi 15221.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000087285 ; ENSMUSP00000084541 ; ENSMUSG00000067261 .
GeneIDi 15221.
KEGGi mmu:15221.
UCSCi uc008tuv.1. mouse.

Organism-specific databases

CTDi 27022.
MGIi MGI:1347473. Foxd3.

Phylogenomic databases

GeneTreei ENSGT00740000115067.
HOGENOMi HOG000231285.
HOVERGENi HBG051641.
InParanoidi A2BDY3.
KOi K09397.
OMAi ALQYPYA.
OrthoDBi EOG7C8GHD.
PhylomeDBi A2BDY3.
TreeFami TF316127.

Miscellaneous databases

NextBioi 287807.
SOURCEi Search...

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
[Graphical view ]
PROSITEi PS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2BDY3_MOUSE
AccessioniPrimary (citable) accession number: A2BDY3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi