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A2BDY3

- A2BDY3_MOUSE

UniProt

A2BDY3 - A2BDY3_MOUSE

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Protein
Submitted name:

Forkhead box protein D3

Gene

Foxd3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. double-stranded DNA binding Source: Ensembl
  2. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
  3. RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: Ensembl
  4. transcription regulatory region DNA binding Source: MGI

GO - Biological processi

  1. embryonic placenta development Source: MGI
  2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  3. transcription, DNA-templated Source: MGI
  4. trophectodermal cell differentiation Source: MGI
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein D3Imported
Gene namesi
Name:Foxd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:1347473. Foxd3.

Subcellular locationi

Nucleus SAAS annotation

GO - Cellular componenti

  1. nuclear chromatin Source: Ensembl
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiA2BDY3.

Expressioni

Gene expression databases

ExpressionAtlasiA2BDY3. baseline.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084541.

Structurei

3D structure databases

ProteinModelPortaliA2BDY3.
SMRiA2BDY3. Positions 130-226.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118904.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.
KOiK09397.
OMAiALQYPYA.
OrthoDBiEOG7C8GHD.
PhylomeDBiA2BDY3.
TreeFamiTF316127.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2BDY3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP
60 70 80 90 100
PDLRLDEADE GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG
110 120 130 140 150
EDAVTGGGGP GAGSGATGGL TPNKPKNSLV KPPYSYIALI TMAILQSPQK
160 170 180 190 200
KLTLSGICEF ISNRFPYYRE KFPAWQNSIR HNLSLNDCFV KIPREPGNPG
210 220 230 240 250
KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA LMMQSFGAYS
260 270 280 290 300
LAAAAGAGPY GRPYGLHPAA AAGAYSHPAA AAAAAAAAAL QYPYALPPVA
310 320 330 340 350
PVLPPAVPLL PSGELGRKAA AFGSQLGPSL QLQLNTLGAA AAAAGTAGAA
360 370 380 390 400
GTTSLIKSEP SARPSFSIEN IIGAGSAAPG GSAGGGGSGG GAGGGGGSGG
410 420 430 440 450
GGGAQSFLRP PGTVQSAALM ATHQPLSLSR TTATIAPILS VPLSGQFLQP
460
AASAAAAAAA AVQAKWPAQ
Length:469
Mass (Da):46,818
Last modified:February 20, 2007 - v1
Checksum:i95E71211C79FAB03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqiNP_034555.3. NM_010425.3.
UniGeneiMm.4758.

Genome annotation databases

EnsembliENSMUST00000087285; ENSMUSP00000084541; ENSMUSG00000067261.
GeneIDi15221.
KEGGimmu:15221.
UCSCiuc008tuv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX005053 Genomic DNA. No translation available.
RefSeqi NP_034555.3. NM_010425.3.
UniGenei Mm.4758.

3D structure databases

ProteinModelPortali A2BDY3.
SMRi A2BDY3. Positions 130-226.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000084541.

Proteomic databases

PRIDEi A2BDY3.

Protocols and materials databases

DNASUi 15221.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000087285 ; ENSMUSP00000084541 ; ENSMUSG00000067261 .
GeneIDi 15221.
KEGGi mmu:15221.
UCSCi uc008tuv.1. mouse.

Organism-specific databases

CTDi 27022.
MGIi MGI:1347473. Foxd3.

Phylogenomic databases

GeneTreei ENSGT00760000118904.
HOGENOMi HOG000231285.
HOVERGENi HBG051641.
KOi K09397.
OMAi ALQYPYA.
OrthoDBi EOG7C8GHD.
PhylomeDBi A2BDY3.
TreeFami TF316127.

Miscellaneous databases

NextBioi 287807.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi A2BDY3. baseline.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
[Graphical view ]
PROSITEi PS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2BDY3_MOUSE
AccessioniPrimary (citable) accession number: A2BDY3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3