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A2BDY3

- A2BDY3_MOUSE

UniProt

A2BDY3 - A2BDY3_MOUSE

Protein
Submitted name:

Forkhead box protein D3

Gene

Foxd3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. double-stranded DNA binding Source: Ensembl
    2. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
    3. RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: Ensembl
    4. transcription regulatory region DNA binding Source: MGI

    GO - Biological processi

    1. embryonic placenta development Source: MGI
    2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    3. transcription, DNA-templated Source: MGI
    4. trophectodermal cell differentiation Source: MGI

    Keywords - Biological processi

    Transcription, Transcription regulationSAAS annotation

    Keywords - Ligandi

    DNA-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Forkhead box protein D3Imported
    Gene namesi
    Name:Foxd3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:1347473. Foxd3.

    Subcellular locationi

    Nucleus SAAS annotation

    GO - Cellular componenti

    1. nuclear chromatin Source: Ensembl
    2. transcription factor complex Source: MGI

    Keywords - Cellular componenti

    NucleusSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiA2BDY3.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000084541.

    Structurei

    3D structure databases

    ProteinModelPortaliA2BDY3.
    SMRiA2BDY3. Positions 130-226.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains fork-head DNA-binding domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115067.
    HOGENOMiHOG000231285.
    HOVERGENiHBG051641.
    InParanoidiA2BDY3.
    KOiK09397.
    OMAiALQYPYA.
    OrthoDBiEOG7C8GHD.
    PhylomeDBiA2BDY3.
    TreeFamiTF316127.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR001766. TF_fork_head.
    IPR018122. TF_fork_head_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00250. Fork_head. 1 hit.
    [Graphical view]
    PRINTSiPR00053. FORKHEAD.
    SMARTiSM00339. FH. 1 hit.
    [Graphical view]
    PROSITEiPS00657. FORK_HEAD_1. 1 hit.
    PS00658. FORK_HEAD_2. 1 hit.
    PS50039. FORK_HEAD_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2BDY3-1 [UniParc]FASTAAdd to Basket

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    MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP    50
    PDLRLDEADE GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG 100
    EDAVTGGGGP GAGSGATGGL TPNKPKNSLV KPPYSYIALI TMAILQSPQK 150
    KLTLSGICEF ISNRFPYYRE KFPAWQNSIR HNLSLNDCFV KIPREPGNPG 200
    KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA LMMQSFGAYS 250
    LAAAAGAGPY GRPYGLHPAA AAGAYSHPAA AAAAAAAAAL QYPYALPPVA 300
    PVLPPAVPLL PSGELGRKAA AFGSQLGPSL QLQLNTLGAA AAAAGTAGAA 350
    GTTSLIKSEP SARPSFSIEN IIGAGSAAPG GSAGGGGSGG GAGGGGGSGG 400
    GGGAQSFLRP PGTVQSAALM ATHQPLSLSR TTATIAPILS VPLSGQFLQP 450
    AASAAAAAAA AVQAKWPAQ 469
    Length:469
    Mass (Da):46,818
    Last modified:February 20, 2007 - v1
    Checksum:i95E71211C79FAB03
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX005053 Genomic DNA. No translation available.
    RefSeqiNP_034555.3. NM_010425.3.
    UniGeneiMm.4758.

    Genome annotation databases

    EnsembliENSMUST00000087285; ENSMUSP00000084541; ENSMUSG00000067261.
    GeneIDi15221.
    KEGGimmu:15221.
    UCSCiuc008tuv.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX005053 Genomic DNA. No translation available.
    RefSeqi NP_034555.3. NM_010425.3.
    UniGenei Mm.4758.

    3D structure databases

    ProteinModelPortali A2BDY3.
    SMRi A2BDY3. Positions 130-226.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000084541.

    Proteomic databases

    PRIDEi A2BDY3.

    Protocols and materials databases

    DNASUi 15221.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000087285 ; ENSMUSP00000084541 ; ENSMUSG00000067261 .
    GeneIDi 15221.
    KEGGi mmu:15221.
    UCSCi uc008tuv.1. mouse.

    Organism-specific databases

    CTDi 27022.
    MGIi MGI:1347473. Foxd3.

    Phylogenomic databases

    GeneTreei ENSGT00740000115067.
    HOGENOMi HOG000231285.
    HOVERGENi HBG051641.
    InParanoidi A2BDY3.
    KOi K09397.
    OMAi ALQYPYA.
    OrthoDBi EOG7C8GHD.
    PhylomeDBi A2BDY3.
    TreeFami TF316127.

    Miscellaneous databases

    NextBioi 287807.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR001766. TF_fork_head.
    IPR018122. TF_fork_head_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00250. Fork_head. 1 hit.
    [Graphical view ]
    PRINTSi PR00053. FORKHEAD.
    SMARTi SM00339. FH. 1 hit.
    [Graphical view ]
    PROSITEi PS00657. FORK_HEAD_1. 1 hit.
    PS00658. FORK_HEAD_2. 1 hit.
    PS50039. FORK_HEAD_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2BDY3_MOUSE
    AccessioniPrimary (citable) accession number: A2BDY3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3