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Protein
Submitted name:

Nucleolar transcription factor 1

Gene

Ubtf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi112 – 180HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi196 – 264HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi298 – 362HMG boxPROSITE-ProRule annotationAdd BLAST65
DNA bindingi407 – 475HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi482 – 549HMG boxPROSITE-ProRule annotationAdd BLAST68
DNA bindingi568 – 634HMG boxPROSITE-ProRule annotationAdd BLAST67

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-73728. RNA Polymerase I Promoter Opening.
R-MMU-73762. RNA Polymerase I Transcription Initiation.
R-MMU-73772. RNA Polymerase I Promoter Escape.
R-MMU-73777. RNA Polymerase I Chain Elongation.
R-MMU-73863. RNA Polymerase I Transcription Termination.

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolar transcription factor 1Imported
Submitted name:
Upstream binding transcription factor, RNA polymerase I, isoform CRA_cImported
Gene namesi
Name:UbtfImported
ORF Names:mCG_140722Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98512. Ubtf.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

MaxQBiA2AWT5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020923.
ExpressionAtlasiA2AWT5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078539.

Structurei

3D structure databases

ProteinModelPortaliA2AWT5.
SMRiA2AWT5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 180HMG box DNA-bindingInterPro annotationAdd BLAST69
Domaini196 – 264HMG box DNA-bindingInterPro annotationAdd BLAST69
Domaini298 – 362HMG box DNA-bindingInterPro annotationAdd BLAST65
Domaini407 – 475HMG box DNA-bindingInterPro annotationAdd BLAST69
Domaini482 – 549HMG box DNA-bindingInterPro annotationAdd BLAST68
Domaini568 – 634HMG box DNA-bindingInterPro annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili674 – 695Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0381. Eukaryota.
COG5648. LUCA.
GeneTreeiENSGT00530000063934.
HOVERGENiHBG008708.
OMAiCSQRWKL.
OrthoDBiEOG091G0GL0.
TreeFamiTF328989.

Family and domain databases

Gene3Di1.10.30.10. 6 hits.
InterProiView protein in InterPro
IPR029215. HMG_box_5.
IPR009071. HMG_box_dom.
PfamiView protein in Pfam
PF00505. HMG_box. 3 hits.
PF09011. HMG_box_2. 1 hit.
PF14887. HMG_box_5. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 6 hits.
SUPFAMiSSF47095. SSF47095. 6 hits.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 6 hits.

Sequencei

Sequence statusi: Complete.

A2AWT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE
60 70 80 90 100
SHMDWEKVAF KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY
110 120 130 140 150
KGKKLKKHPD FPKKPLTPYF RFFMEKRAKY AKLHPEMSNL DLTKILSKKY
160 170 180 190 200
KELPEKKKMK YIQDFQREKQ EFERNLARFR EDHPDLIQNA KKSDIPEKPK
210 220 230 240 250
TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK KRLKWIHKAL
260 270 280 290 300
EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP
310 320 330 340 350
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK
360 370 380 390 400
KKDYEVELLR FLESLPEEEQ QRVLGEEKML NINKKQTTSP ASKKPSQEGG
410 420 430 440 450
KGGSEKPKRP VSAMFIFSEE KRRQLQEERP ELSESELTRL LARMWNDLSE
460 470 480 490 500
KKKAKYKARE AALKAQSERK PGGEREDRGK LPESPKRAEE IWQQSVIGDY
510 520 530 540 550
LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR YERELSEMRA
560 570 580 590 600
PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
610 620 630 640 650
GSRWQRISQS QKEHYKKLAE EQQRQYKVHL DLWVKSLSPQ DRAAYKEYIS
660 670 680 690 700
NKRKNMTKLR GPNPKSSRTT LQSKSESEED DDEEEEDDEE EEEEEDDENG
710 720 730 740 750
DSSEDGGDSS ESSSEDESED GDENDDDDDD EDDEDDDDED EDNESEGSSS
760
SSSSSGDSSD SDSN
Length:764
Mass (Da):89,479
Last modified:February 20, 2007 - v1
Checksum:i788C8822CFEE5070
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954730 Genomic DNA. No translation available.
CH466558 Genomic DNA. Translation: EDL34113.1.
RefSeqiNP_035681.2. NM_011551.6.
XP_011247190.1. XM_011248888.2.
XP_011247191.1. XM_011248889.2.
UniGeneiMm.2845.

Genome annotation databases

EnsembliENSMUST00000079589; ENSMUSP00000078539; ENSMUSG00000020923.
ENSMUST00000107123; ENSMUSP00000102740; ENSMUSG00000020923.
ENSMUST00000173870; ENSMUSP00000133611; ENSMUSG00000020923.
ENSMUST00000174302; ENSMUSP00000133844; ENSMUSG00000020923.
GeneIDi21429.
UCSCiuc007lri.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954730 Genomic DNA. No translation available.
CH466558 Genomic DNA. Translation: EDL34113.1.
RefSeqiNP_035681.2. NM_011551.6.
XP_011247190.1. XM_011248888.2.
XP_011247191.1. XM_011248889.2.
UniGeneiMm.2845.

3D structure databases

ProteinModelPortaliA2AWT5.
SMRiA2AWT5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078539.

Proteomic databases

MaxQBiA2AWT5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000079589; ENSMUSP00000078539; ENSMUSG00000020923.
ENSMUST00000107123; ENSMUSP00000102740; ENSMUSG00000020923.
ENSMUST00000173870; ENSMUSP00000133611; ENSMUSG00000020923.
ENSMUST00000174302; ENSMUSP00000133844; ENSMUSG00000020923.
GeneIDi21429.
UCSCiuc007lri.2. mouse.

Organism-specific databases

CTDi7343.
MGIiMGI:98512. Ubtf.

Phylogenomic databases

eggNOGiKOG0381. Eukaryota.
COG5648. LUCA.
GeneTreeiENSGT00530000063934.
HOVERGENiHBG008708.
OMAiCSQRWKL.
OrthoDBiEOG091G0GL0.
TreeFamiTF328989.

Enzyme and pathway databases

ReactomeiR-MMU-73728. RNA Polymerase I Promoter Opening.
R-MMU-73762. RNA Polymerase I Transcription Initiation.
R-MMU-73772. RNA Polymerase I Promoter Escape.
R-MMU-73777. RNA Polymerase I Chain Elongation.
R-MMU-73863. RNA Polymerase I Transcription Termination.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020923.
ExpressionAtlasiA2AWT5. baseline and differential.

Family and domain databases

Gene3Di1.10.30.10. 6 hits.
InterProiView protein in InterPro
IPR029215. HMG_box_5.
IPR009071. HMG_box_dom.
PfamiView protein in Pfam
PF00505. HMG_box. 3 hits.
PF09011. HMG_box_2. 1 hit.
PF14887. HMG_box_5. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 6 hits.
SUPFAMiSSF47095. SSF47095. 6 hits.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 6 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA2AWT5_MOUSE
AccessioniPrimary (citable) accession number: A2AWT5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: April 12, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.