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Protein
Submitted name:

Nucleolar transcription factor 1

Gene

Ubtf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi112 – 180HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi196 – 264HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi298 – 362HMG boxPROSITE-ProRule annotationAdd BLAST65
DNA bindingi407 – 475HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi482 – 549HMG boxPROSITE-ProRule annotationAdd BLAST68
DNA bindingi568 – 634HMG boxPROSITE-ProRule annotationAdd BLAST67

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-73728 RNA Polymerase I Promoter Opening
R-MMU-73762 RNA Polymerase I Transcription Initiation
R-MMU-73772 RNA Polymerase I Promoter Escape
R-MMU-73777 RNA Polymerase I Chain Elongation
R-MMU-73863 RNA Polymerase I Transcription Termination

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolar transcription factor 1Imported
Submitted name:
Upstream binding transcription factor, RNA polymerase I, isoform CRA_cImported
Gene namesi
Name:UbtfImported
ORF Names:mCG_140722Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98512 Ubtf

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

MaxQBiA2AWT5
PeptideAtlasiA2AWT5

Expressioni

Gene expression databases

BgeeiENSMUSG00000020923

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA2AWT5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 180HMG boxInterPro annotationAdd BLAST69
Domaini196 – 264HMG boxInterPro annotationAdd BLAST69
Domaini298 – 362HMG boxInterPro annotationAdd BLAST65
Domaini407 – 475HMG boxInterPro annotationAdd BLAST69
Domaini482 – 549HMG boxInterPro annotationAdd BLAST68
Domaini568 – 634HMG boxInterPro annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili162 – 182Sequence analysisAdd BLAST21
Coiled coili246 – 266Sequence analysisAdd BLAST21
Coiled coili674 – 695Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0381 Eukaryota
COG5648 LUCA
GeneTreeiENSGT00530000063934
HOVERGENiHBG008708
OMAiKAMEATW
OrthoDBiEOG091G0GL0
TreeFamiTF328989

Family and domain databases

Gene3Di1.10.30.10, 6 hits
InterProiView protein in InterPro
IPR029215 HMG_box_5
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
PfamiView protein in Pfam
PF00505 HMG_box, 3 hits
PF09011 HMG_box_2, 1 hit
PF14887 HMG_box_5, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 6 hits
SUPFAMiSSF47095 SSF47095, 6 hits
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 6 hits

Sequencei

Sequence statusi: Complete.

A2AWT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE
60 70 80 90 100
SHMDWEKVAF KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY
110 120 130 140 150
KGKKLKKHPD FPKKPLTPYF RFFMEKRAKY AKLHPEMSNL DLTKILSKKY
160 170 180 190 200
KELPEKKKMK YIQDFQREKQ EFERNLARFR EDHPDLIQNA KKSDIPEKPK
210 220 230 240 250
TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK KRLKWIHKAL
260 270 280 290 300
EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP
310 320 330 340 350
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK
360 370 380 390 400
KKDYEVELLR FLESLPEEEQ QRVLGEEKML NINKKQTTSP ASKKPSQEGG
410 420 430 440 450
KGGSEKPKRP VSAMFIFSEE KRRQLQEERP ELSESELTRL LARMWNDLSE
460 470 480 490 500
KKKAKYKARE AALKAQSERK PGGEREDRGK LPESPKRAEE IWQQSVIGDY
510 520 530 540 550
LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR YERELSEMRA
560 570 580 590 600
PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
610 620 630 640 650
GSRWQRISQS QKEHYKKLAE EQQRQYKVHL DLWVKSLSPQ DRAAYKEYIS
660 670 680 690 700
NKRKNMTKLR GPNPKSSRTT LQSKSESEED DDEEEEDDEE EEEEEDDENG
710 720 730 740 750
DSSEDGGDSS ESSSEDESED GDENDDDDDD EDDEDDDDED EDNESEGSSS
760
SSSSSGDSSD SDSN
Length:764
Mass (Da):89,479
Last modified:February 20, 2007 - v1
Checksum:i788C8822CFEE5070
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954730 Genomic DNA No translation available.
CH466558 Genomic DNA Translation: EDL34113.1
RefSeqiNP_035681.2, NM_011551.6
XP_011247190.1, XM_011248888.2
XP_011247191.1, XM_011248889.2
UniGeneiMm.2845

Genome annotation databases

EnsembliENSMUST00000079589; ENSMUSP00000078539; ENSMUSG00000020923
ENSMUST00000107123; ENSMUSP00000102740; ENSMUSG00000020923
ENSMUST00000173870; ENSMUSP00000133611; ENSMUSG00000020923
ENSMUST00000174302; ENSMUSP00000133844; ENSMUSG00000020923
GeneIDi21429
UCSCiuc007lri.2 mouse

Similar proteinsi

Entry informationi

Entry nameiA2AWT5_MOUSE
AccessioniPrimary (citable) accession number: A2AWT5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health