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Protein
Submitted name:

Nucleolar transcription factor 1

Gene

Ubtf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi112 – 180HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi196 – 264HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi298 – 362HMG boxPROSITE-ProRule annotationAdd BLAST65
DNA bindingi407 – 475HMG boxPROSITE-ProRule annotationAdd BLAST69
DNA bindingi482 – 549HMG boxPROSITE-ProRule annotationAdd BLAST68
DNA bindingi568 – 634HMG boxPROSITE-ProRule annotationAdd BLAST67

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-73728. RNA Polymerase I Promoter Opening.
R-MMU-73762. RNA Polymerase I Transcription Initiation.
R-MMU-73772. RNA Polymerase I Promoter Escape.
R-MMU-73777. RNA Polymerase I Chain Elongation.
R-MMU-73863. RNA Polymerase I Transcription Termination.

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolar transcription factor 1Imported
Submitted name:
Upstream binding transcription factor, RNA polymerase I, isoform CRA_cImported
Gene namesi
Name:UbtfImported
ORF Names:mCG_140722Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98512. Ubtf.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000020923.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 180HMG boxInterPro annotationAdd BLAST69
Domaini196 – 264HMG boxInterPro annotationAdd BLAST69
Domaini298 – 362HMG boxInterPro annotationAdd BLAST65
Domaini407 – 475HMG boxInterPro annotationAdd BLAST69
Domaini482 – 549HMG boxInterPro annotationAdd BLAST68
Domaini568 – 634HMG boxInterPro annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili674 – 695Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0381. Eukaryota.
COG5648. LUCA.
GeneTreeiENSGT00530000063934.
HOVERGENiHBG008708.
OMAiCSQRWKL.
OrthoDBiEOG091G0GL0.
TreeFamiTF328989.

Family and domain databases

Gene3Di1.10.30.10. 6 hits.
InterProiView protein in InterPro
IPR029215. HMG_box_5.
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
PfamiView protein in Pfam
PF00505. HMG_box. 3 hits.
PF09011. HMG_box_2. 1 hit.
PF14887. HMG_box_5. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 6 hits.
SUPFAMiSSF47095. SSF47095. 6 hits.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 6 hits.

Sequencei

Sequence statusi: Complete.

A2AWT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE
60 70 80 90 100
SHMDWEKVAF KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY
110 120 130 140 150
KGKKLKKHPD FPKKPLTPYF RFFMEKRAKY AKLHPEMSNL DLTKILSKKY
160 170 180 190 200
KELPEKKKMK YIQDFQREKQ EFERNLARFR EDHPDLIQNA KKSDIPEKPK
210 220 230 240 250
TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK KRLKWIHKAL
260 270 280 290 300
EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP
310 320 330 340 350
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK
360 370 380 390 400
KKDYEVELLR FLESLPEEEQ QRVLGEEKML NINKKQTTSP ASKKPSQEGG
410 420 430 440 450
KGGSEKPKRP VSAMFIFSEE KRRQLQEERP ELSESELTRL LARMWNDLSE
460 470 480 490 500
KKKAKYKARE AALKAQSERK PGGEREDRGK LPESPKRAEE IWQQSVIGDY
510 520 530 540 550
LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR YERELSEMRA
560 570 580 590 600
PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
610 620 630 640 650
GSRWQRISQS QKEHYKKLAE EQQRQYKVHL DLWVKSLSPQ DRAAYKEYIS
660 670 680 690 700
NKRKNMTKLR GPNPKSSRTT LQSKSESEED DDEEEEDDEE EEEEEDDENG
710 720 730 740 750
DSSEDGGDSS ESSSEDESED GDENDDDDDD EDDEDDDDED EDNESEGSSS
760
SSSSSGDSSD SDSN
Length:764
Mass (Da):89,479
Last modified:February 20, 2007 - v1
Checksum:i788C8822CFEE5070
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954730 Genomic DNA. No translation available.
CH466558 Genomic DNA. Translation: EDL34113.1.
RefSeqiNP_035681.2. NM_011551.6.
XP_011247190.1. XM_011248888.2.
XP_011247191.1. XM_011248889.2.
UniGeneiMm.2845.

Genome annotation databases

EnsembliENSMUST00000079589; ENSMUSP00000078539; ENSMUSG00000020923.
ENSMUST00000107123; ENSMUSP00000102740; ENSMUSG00000020923.
ENSMUST00000173870; ENSMUSP00000133611; ENSMUSG00000020923.
ENSMUST00000174302; ENSMUSP00000133844; ENSMUSG00000020923.
GeneIDi21429.
UCSCiuc007lri.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiA2AWT5_MOUSE
AccessioniPrimary (citable) accession number: A2AWT5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 22, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported