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A2AT91 (A2AT91_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length883 AA.
Sequence statusFragment.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol. RuleBase RU361133

Sequence similarities

Contains 1 C2 domain. RuleBase RU361133

Contains 1 PI-PLC X-box domain. RuleBase RU361133

Contains 1 PI-PLC Y-box domain. RuleBase RU361133

Contains C2 domain. SAAS SAAS015359

Contains Cdomain. SAAS SAAS015359

Contains PI-PLC X-box domain. SAAS SAAS015359

Contains PI-PLC Y-box domain. SAAS SAAS015359

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000117638

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue8831 Ensembl ENSMUSP00000117638

Sequences

Sequence LengthMass (Da)Tools
A2AT91 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 240286DCACF11AF6

FASTA883100,651
        10         20         30         40         50         60 
MAKPYEFNWQ KEVPSFLQEG AVFDRYEEES FVFEPNCLFK VDEFGFFLTW KSEGKEGQVL 

        70         80         90        100        110        120 
ECSLINSIRQ AAIPKDPKIL AALEAVGKSE NDLEGRILCV CSGTDLVNIG FTYMVAENPE 

       130        140        150        160        170        180 
VTKQWVEGLR SIIHNFRANN VSPMTCLKKH WMKLAFLTNT TGKIPVRSIT RTFASGKTEK 

       190        200        210        220        230        240 
VIFQALKELG LPSGKNDEIE PAAFTYEKFY ELTQKICPRT DIEDLFKKIN GDKTDYLTVD 

       250        260        270        280        290        300 
QLVSFLNEHQ RDPRLNEILF PFYDAKRAMQ IIEMYEPDEE LKKKGLISSD GFCRYLMSDE 

       310        320        330        340        350        360 
NAPVFLDRLE LYQEMDHPLA HYFISSSHNT YLTGRQFGGK SSVEMYRQVL LAGCRCVELD 

       370        380        390        400        410        420 
CWDGKGEDQE PIITHGKAMC TDILFKDVIQ AIKETAFVTS EYPVILSFEN HCSKYQQYKM 

       430        440        450        460        470        480 
SKYCEDLFGD LLLKQALESH PLEPGRPLPS PNDLKRKILI KNKRLKPEVE KKQLEALKSM 

       490        500        510        520        530        540 
MEAGESAAPA SILEDDNEEE IESADQEEEA HPEYKFGNEL SADDYSHKEA VANSVKKTSD 

       550        560        570        580        590        600 
DLEHENNKKG LVTVEDEQAW MASYKYVGAT TNIHPYLSTM INYAQPVKFQ GFHVAEERNI 

       610        620        630        640        650        660 
HYNMSSFNES VGLGYLKTHA IEFVNYNKRQ MSRIYPKGGR VDSSNYMPQI FWNAGCQMVS 

       670        680        690        700        710        720 
LNYQTPDLAM QLNQGKFEYN GSCGYLLKPD FMRRPDRTFD PFSETPVDGV IAATCSVQVI 

       730        740        750        760        770        780 
SGQFLSDKKI GTYVEVDMYG LPTDTIRKEF RTRMVMNNGL NPVYNEESFV FRKVILPDLA 

       790        800        810        820        830        840 
VLRIAVYDDN NKLIGQRILP LDGLQAGYRH ISLRNEGNKP LSLPTIFCNI VLKTYVPDGF 

       850        860        870        880 
GDIVDALSDP KKFLSITEKR ADQMRAMGIE TSDIADVPSD TSK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL928798 Genomic DNA. No translation available.
AL929052 Genomic DNA. No translation available.
AL935301 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalA2AT91.
SMRA2AT91. Positions 5-872.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbA2AT91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000134310; ENSMUSP00000117638; ENSMUSG00000039943.
UCSCuc008mob.1. mouse.

Organism-specific databases

MGIMGI:107464. Plcb4.

Phylogenomic databases

eggNOGNOG149692.
GeneTreeENSGT00730000110266.
HOGENOMHOG000232046.
HOVERGENHBG053609.
OrthoDBEOG7WDN1N.

Gene expression databases

ArrayExpressA2AT91.

Family and domain databases

Gene3D1.10.238.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.150. 1 hit.
3.20.20.190. 2 hits.
InterProIPR000008. C2_dom.
IPR011992. EF-hand-dom_pair.
IPR011993. PH_like_dom.
IPR001192. PI-PLC_fam.
IPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR015359. PLipase_C_EF-hand-like.
IPR000909. PLipase_C_PInositol-sp_X_dom.
IPR001711. PLipase_C_Pinositol-sp_Y.
[Graphical view]
PANTHERPTHR10336. PTHR10336. 1 hit.
PfamPF00168. C2. 1 hit.
PF09279. EF-hand_like. 1 hit.
PF00388. PI-PLC-X. 1 hit.
PF00387. PI-PLC-Y. 1 hit.
[Graphical view]
PRINTSPR00390. PHPHLIPASEC.
SMARTSM00239. C2. 1 hit.
SM00148. PLCXc. 1 hit.
SM00149. PLCYc. 1 hit.
[Graphical view]
SUPFAMSSF49562. SSF49562. 1 hit.
SSF51695. SSF51695. 2 hits.
PROSITEPS50004. C2. 1 hit.
PS50007. PIPLC_X_DOMAIN. 1 hit.
PS50008. PIPLC_Y_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35544084.
SOURCESearch...

Entry information

Entry nameA2AT91_MOUSE
AccessionPrimary (citable) accession number: A2AT91
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 9, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)