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Protein

Ankyrin repeat domain-containing protein 16

Gene

Ankrd16

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 16
Gene namesi
Name:Ankrd16
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2444796. Ankrd16.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003200681 – 361Ankyrin repeat domain-containing protein 16Add BLAST361

Proteomic databases

MaxQBiA2AS55.
PaxDbiA2AS55.
PRIDEiA2AS55.

PTM databases

PhosphoSitePlusiA2AS55.

Expressioni

Gene expression databases

BgeeiENSMUSG00000047909.
CleanExiMM_ANKRD16.
ExpressionAtlasiA2AS55. baseline and differential.
GenevisibleiA2AS55. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052056.

Structurei

3D structure databases

ProteinModelPortaliA2AS55.
SMRiA2AS55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati36 – 66ANK 1Add BLAST31
Repeati70 – 99ANK 2Add BLAST30
Repeati103 – 132ANK 3Add BLAST30
Repeati136 – 165ANK 4Add BLAST30
Repeati170 – 200ANK 5Add BLAST31
Repeati204 – 233ANK 6Add BLAST30
Repeati238 – 268ANK 7Add BLAST31
Repeati273 – 302ANK 8Add BLAST30
Repeati306 – 335ANK 9Add BLAST30

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00900000140877.
HOGENOMiHOG000015234.
HOVERGENiHBG056770.
InParanoidiA2AS55.
OMAiSCGVTPF.
OrthoDBiEOG091G0AGX.
PhylomeDBiA2AS55.
TreeFamiTF329520.

Family and domain databases

CDDicd00204. ANK. 2 hits.
Gene3Di1.25.40.20. 4 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
PfamiView protein in Pfam
PF00023. Ank. 1 hit.
PF12796. Ank_2. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 9 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A2AS55-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MALPGDPRRL CRLVQEGRLR DLQEELAVAR GCRGPAGDTL LHCAARHGRQ
60 70 80 90 100
DILAYLVEAW SMDIEATNRD YKRPLHEAAS MGHRDCVRYL LGRGAVVDSL
110 120 130 140 150
KKADWTPLMM ACTRKNLDVI QDLVEHGANP LLKNKDGWNS FHIASREGHP
160 170 180 190 200
VILRYLLTVC PDAWKTESNI RRTPLHTAAM HGCLEAVQVL LERCHYEPDC
210 220 230 240 250
RDNCGVTPFM DAIQCGHVSI AKLLLEQHKA CSSAADSMGA QALHRAAVTG
260 270 280 290 300
QDEAIRFLVC GLGIDVDVRA KSSQLTALHY AAKEGQTNTV QTLLSLGADI
310 320 330 340 350
NSTDERNRSV LHLACAGQHV ACTRLLLQSG LKDSEDLTGT LAQQLTRSVD
360
ILQDFDHDVK S
Length:361
Mass (Da):39,776
Last modified:February 20, 2007 - v1
Checksum:i4570C30C3B1316CA
GO
Isoform 2 (identifier: A2AS55-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     179-187: AMHGCLEAV → GTPCKLWSL
     188-361: Missing.

Show »
Length:187
Mass (Da):21,083
Checksum:i42AB7F73A64785CC
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_031593179 – 187AMHGCLEAV → GTPCKLWSL in isoform 2. 2 Publications9
Alternative sequenceiVSP_031594188 – 361Missing in isoform 2. 2 PublicationsAdd BLAST174

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052460 mRNA. Translation: BAC35002.1.
AK085853 mRNA. Translation: BAC39552.1.
AL845548 Genomic DNA. Translation: CAM20367.1.
BC116229 mRNA. Translation: AAI16230.1.
BC116230 mRNA. Translation: AAI16231.1.
CCDSiCCDS50502.1. [A2AS55-1]
RefSeqiNP_796242.2. NM_177268.4. [A2AS55-1]
UniGeneiMm.260201.

Genome annotation databases

EnsembliENSMUST00000056108; ENSMUSP00000052056; ENSMUSG00000047909. [A2AS55-1]
GeneIDi320816.
KEGGimmu:320816.
UCSCiuc008ijg.2. mouse. [A2AS55-2]
uc012bqv.1. mouse. [A2AS55-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiANR16_MOUSE
AccessioniPrimary (citable) accession number: A2AS55
Secondary accession number(s): Q8BH84
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 20, 2007
Last modified: October 25, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot