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Protein
Submitted name:

Protein Slc2a6

Gene

Slc2a6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. substrate-specific transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_206357. Facilitative Na+-independent glucose transporters.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Slc2a6Imported
Submitted name:
Slc2a6 proteinImported
Gene namesi
Name:Slc2a6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:2443286. Slc2a6.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriA2AR26.

Structurei

3D structure databases

ProteinModelPortaliA2AR26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00720000108754.
HOGENOMiHOG000202868.
HOVERGENiHBG104335.
KOiK08144.
OrthoDBiEOG7N8ZV9.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2AR26-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEPLLRTEG LDYDTFPEVP ATPGERERAG ALKNRRVFLA TFAAVLGNFS
60 70 80 90 100
FGYALVYTSP VIPELKLSSD PALHLDKIQA SWFGSVFTLG AAAGGLSAML
110 120 130 140 150
LNDLLGRKLS IMFSAVPSAI GYAIMAGARG LWMLLLGRML TGFAGGLTAA
160 170 180 190 200
CIPVYVSEIA PPDVRGALGA TPQLMAVFGS LSLYALGLLL PWRWLAVAGE
210 220 230 240 250
GPVLIMILLL SFMPNSPRFL LSKSRDEEAL QALTWLRADS EVHWEFEQIQ
260 270 280 290 300
DNVRRQSSRV SWAEAREPRV YRPVLIAVLM RFLQQLTGIT PILVYLQTIF
310 320 330 340 350
DNTSVVLPSQ QDAAIVGAVR LLSVLIAAVT MDLAGRKVLL YVSGYAMGWG
360 370 380 390 400
PITWLLMSEV LPLRARGVAS GLCVLVSWLT AFVLTNYFLL AVNAFGLQVP
410 420 430 440
FFFFSAICLL SLLFTGCCVP ETRGRSLEQI EAFFHTRRMS FRP
Length:443
Mass (Da):48,547
Last modified:February 20, 2007 - v1
Checksum:iC71F0A6599615863
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845266 Genomic DNA. No translation available.
BC141168 mRNA. Translation: AAI41169.1.
RefSeqiNP_001171098.1. NM_001177627.1.
UniGeneiMm.41203.

Genome annotation databases

EnsembliENSMUST00000102890; ENSMUSP00000099954; ENSMUSG00000036067.
GeneIDi227659.
KEGGimmu:227659.
UCSCiuc008iww.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845266 Genomic DNA. No translation available.
BC141168 mRNA. Translation: AAI41169.1.
RefSeqiNP_001171098.1. NM_001177627.1.
UniGeneiMm.41203.

3D structure databases

ProteinModelPortaliA2AR26.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi227659.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102890; ENSMUSP00000099954; ENSMUSG00000036067.
GeneIDi227659.
KEGGimmu:227659.
UCSCiuc008iww.1. mouse.

Organism-specific databases

CTDi11182.
MGIiMGI:2443286. Slc2a6.

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00720000108754.
HOGENOMiHOG000202868.
HOVERGENiHBG104335.
KOiK08144.
OrthoDBiEOG7N8ZV9.

Enzyme and pathway databases

ReactomeiREACT_206357. Facilitative Na+-independent glucose transporters.

Miscellaneous databases

NextBioi378728.
SOURCEiSearch...

Gene expression databases

GenevestigatoriA2AR26.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AR26_MOUSE
AccessioniPrimary (citable) accession number: A2AR26
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: February 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.