Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase

Gene

Gpd2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:Gpd2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:99778. Gpd2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA2AQR0.
PeptideAtlasiA2AQR0.
PRIDEiA2AQR0.

Expressioni

Gene expression databases

BgeeiA2AQR0.
ExpressionAtlasiA2AQR0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028167.

Structurei

3D structure databases

ProteinModelPortaliA2AQR0.
SMRiA2AQR0. Positions 92-588, 597-709.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini641 – 67636EF-handInterPro annotationAdd
BLAST
Domaini677 – 71236EF-handInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0042. Eukaryota.
COG0578. LUCA.
GeneTreeiENSGT00390000001718.
HOGENOMiHOG000004813.
HOVERGENiHBG005897.
OMAiCIVNAAG.
OrthoDBiEOG74TWZ2.
PhylomeDBiA2AQR0.
TreeFamiTF300359.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR031656. DAO_C.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF16901. DAO_C. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF51905. SSF51905. 2 hits.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2AQR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFQKAVKGT ILVGGGALAT VLGLSPFAHY RRKQVSLAYV EAAGYLTEPV
60 70 80 90 100
NREPPSREAQ LMTLKNTPEF DILVIGGGAT GCGCALDAVT RGLKTALVER
110 120 130 140 150
DDFSSGTSSR STKLIHGGVR YLQKAIMNLD VEQYRMVKEA LHERANLLEI
160 170 180 190 200
APHLSAPLPI MLPLYKWWQL PYYWVGIKMY DLVAGSQCLK SSYVLSKSRA
210 220 230 240 250
LEHFPMLQKD KLVGAIVYYD GQHNDARMNL AIALTAARYG AATANYMEVV
260 270 280 290 300
SLLKKTDPET GKERVSGARC KDVLTGQEFD VRAKCVINAS GPFTDSVRKM
310 320 330 340 350
DDKNVVPICQ PSAGVHIVMP GYYSPENMGL LDPATSDGRV IFFLPWEKMT
360 370 380 390 400
IAGTTDTPTD VTHHPIPSEE DINFILNEVR NYLSSDVEVR RGDVLAAWSG
410 420 430 440 450
IRPLVTDPKS ADTQSISRNH VVDISDSGLI TIAGGKWTTY RSMAEDTVDA
460 470 480 490 500
AVKFHNLNAG PSRTVGLFLQ GGKDWSPTLY IRLVQDYGLE SEVAQHLAKT
510 520 530 540 550
YGDKAFEVAK MASVTGKRWP VVGVRLVSEF PYIEAEVKYG IKEYACTAVD
560 570 580 590 600
MISRRTRLAF LNVQAAEEAL PRIVELMGRE LNWSELRKQC VTYDSDGSTV
610 620 630 640 650
ATSWSSQEEL ETATRFLYYE MGYKSRTEQL TDSTEISLLP SDIDRYKKRF
660 670 680 690 700
HKFDEDEKGF ITIVDVQRVL ESINVQMDEN TLHEILCEVD LNKNGQVELH
710 720 730 740
EFLQLMSAVQ KGRVSGSRLA ILMKTAEENL DRRVPIPVDR SCGGL
Length:745
Mass (Da):82,830
Last modified:February 20, 2007 - v1
Checksum:iCCFCDECCCE414876
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844871 Genomic DNA. No translation available.
AL845166 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000112618; ENSMUSP00000108237; ENSMUSG00000026827.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844871 Genomic DNA. No translation available.
AL845166 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA2AQR0.
SMRiA2AQR0. Positions 92-588, 597-709.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028167.

Proteomic databases

PaxDbiA2AQR0.
PeptideAtlasiA2AQR0.
PRIDEiA2AQR0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112618; ENSMUSP00000108237; ENSMUSG00000026827.

Organism-specific databases

MGIiMGI:99778. Gpd2.

Phylogenomic databases

eggNOGiKOG0042. Eukaryota.
COG0578. LUCA.
GeneTreeiENSGT00390000001718.
HOGENOMiHOG000004813.
HOVERGENiHBG005897.
OMAiCIVNAAG.
OrthoDBiEOG74TWZ2.
PhylomeDBiA2AQR0.
TreeFamiTF300359.

Miscellaneous databases

ChiTaRSiGpd2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiA2AQR0.
ExpressionAtlasiA2AQR0. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR031656. DAO_C.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF16901. DAO_C. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF51905. SSF51905. 2 hits.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
    Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
    J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AQR0_MOUSE
AccessioniPrimary (citable) accession number: A2AQR0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 6, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.