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A2AQM9

- A2AQM9_MOUSE

UniProt

A2AQM9 - A2AQM9_MOUSE

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Protein
Submitted name:

Nuclear receptor coactivator 6

Gene
Ncoa6
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. ligand-dependent nuclear receptor transcription coactivator activity Source: Ensembl
  3. transcription coactivator activity Source: MGI

GO - Biological processi

  1. brain development Source: MGI
  2. cellular response to DNA damage stimulus Source: MGI
  3. DNA-templated transcription, initiation Source: Ensembl
  4. heart development Source: MGI
  5. labyrinthine layer blood vessel development Source: MGI
  6. myeloid cell differentiation Source: Ensembl
  7. positive regulation of transcription, DNA-templated Source: MGI
  8. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_118837. Rora activates circadian gene expression.
REACT_196516. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_198351. RORA activates circadian gene expression.
REACT_198352. REV-ERBA represses gene expression.
REACT_198602. PPARA activates gene expression.
REACT_198969. Activation of gene expression by SREBF (SREBP).
REACT_205251. Transcriptional activation of mitochondrial biogenesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor coactivator 6Imported
Gene namesi
Name:Ncoa6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:1929915. Ncoa6.

Subcellular locationi

GO - Cellular componenti

  1. histone methyltransferase complex Source: MGI
  2. nucleus Source: MGI
  3. transcription factor complex Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA2AQM9.

Expressioni

Gene expression databases

ArrayExpressiA2AQM9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045386.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00730000111114.
HOGENOMiHOG000113745.
HOVERGENiHBG052586.
InParanoidiA2AQM9.
OrthoDBiEOG7W9RSX.

Family and domain databases

InterProiIPR026638. NCOA6.
[Graphical view]
PANTHERiPTHR15690. PTHR15690. 1 hit.

Sequencei

Sequence statusi: Fragment.

A2AQM9-1 [UniParc]FASTAAdd to Basket

« Hide

MVLDDLPNFE DIYTSLCSST MGDSEVEFDS GLEDDDTKSD SILEDSTIFV     50
AFKGNIDDKD FKWKLDAILK NVPNLLHMES SKLKVQKVEP WNSVRVTFNI 100
PREAAERLRI LAQSNNQQLR DLGILSVQIE GEGAINLALG QNRSQDVRMN 150
GPVASGNSVR MEAGFPMASG PGLIRMTSPA AVMTPQGGNM SSSMMAPGPN 200
PELQPRTPRP ASQSDAMDPL LSGLHIQQQS HPSGSLPPAH HSMQPVPVNR 250
QMNPANFPQL QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQLQTRPLQQ 300
HQQQPQGIRP QFTAPTQVPV PPGWNQLPSG ALQPPPAQGS LGTMTTNQGW 350
KKAPLPSPMQ AQLQARPSLA TVQTPSHPPP PYPFGSQQAS QAHTNFPQMS 400
NPGQFTAPQM KGLQGGPSRV PTPLQQPHLT NKSPASSPSS FQQGSPASSP 450
TVNQTQQQMG PRPPQNNPLS QGFQQPVSSP GRNPMVQQGN VPPNFMVMQQ 500
QPPNQGPQSL HPGLGGMPKR LPPGFSAGQA NPNFMQGQVP STTAATPGNS 550
GALQLQANQN VQHAGGQGAG PPQNQMQVSH GPPNMMQPSL MGIHGNINNQ 600
QAGSSGVPQV TLGNMQGQPQ QGPPSQLMGM HQQIVPSQGQ MAQQQGTLNP 650
QNPMILSRAQ LMPQGQMMVN AQNQNLGPSP QRMTPPKQML PQQGPQMMAP 700
HNQMMGPQGQ VLLQQNPMIE QIMTNQMQGN KAQFNSQNQS NVMPGPAQIM 750
RGPTPNMQGN MVQFTGQMSG QMLPQQGPVN NSPSQVMGIQ GQVLRPPGPS 800
PHMAQQHNDP VTTANNDVNL SQMMPDVSMQ QASMVPPHVQ SMQGNSASGS 850
HFSGHGVSFN APFGGAPNGS QMSCGQNPGF PVNKDVTLTS PLLVNLLQSD 900
ISAGHFGVNN KQNNTNANKP KKKKPPRKKK NCHQDLNTPD NRPTGLEEVD 950
QQSLPGEQGI NLDTTGPKLP DFSNRPPGYP TQPVEQRPLP QMPPQLMQHV 1000
APPPQPPQQQ PQPQLPQQQQ PPPPSQPQSQ QQQQQQQMMM MLMMQQDPKS 1050
IRLPVSQNVH PPRGPLNPDS QRMPVQQSGN VPVMVGLQGP ASVPPSPDKQ 1100
RMPMSVNTPM GSNSRKMVYQ ENPQNSSSSP LGEMSSLPEA SGSEVPSVAG 1150
GPNNMPSHLV VSQNQLMMTG PKPGPSPLSA TQGATPQQPP VNSLPSSHGH 1200
HFPNVAAPTQ TSRPKTPNRA SPRPYYPQTP NNRPPSTEPS EISLSPERLN 1250
ASIAGLFPPQ INIPLPPRPN LNRGFDQQGL NPTTLKAIGQ APSNLTITNP 1300
PNFAAPQAHK LDSVVVNSGK QSNPGTTKRA SPSNSRRSSP GSSRKTTPSP 1350
GRQNSKAPKL TLASQTSTTM LQNMELPRNV LVGPTPLANP PLPGSFPNNT 1400
GLNPQNPTVP VPAMGTVLED NKESVNIPQD SDCQNAQGRK EQVNTELKVV 1450
PTQEAKMAVP EDQSKKDGQP LDPNKLPSVE ENKNLMSPAM REAPTSLSQL 1500
LDNSGAPNVT IKPPGL 1516
Length:1,516
Mass (Da):163,093
Last modified:May 14, 2014 - v2
Checksum:i7644982132B39798
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1516 – 15161Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL844852 Genomic DNA. No translation available.
AL845325 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000123293; ENSMUSP00000118113; ENSMUSG00000038369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL844852 Genomic DNA. No translation available.
AL845325 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000045386.

Proteomic databases

PRIDEi A2AQM9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000123293 ; ENSMUSP00000118113 ; ENSMUSG00000038369 .

Organism-specific databases

MGIi MGI:1929915. Ncoa6.

Phylogenomic databases

GeneTreei ENSGT00730000111114.
HOGENOMi HOG000113745.
HOVERGENi HBG052586.
InParanoidi A2AQM9.
OrthoDBi EOG7W9RSX.

Enzyme and pathway databases

Reactomei REACT_118837. Rora activates circadian gene expression.
REACT_196516. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_198351. RORA activates circadian gene expression.
REACT_198352. REV-ERBA represses gene expression.
REACT_198602. PPARA activates gene expression.
REACT_198969. Activation of gene expression by SREBF (SREBP).
REACT_205251. Transcriptional activation of mitochondrial biogenesis.

Miscellaneous databases

ChiTaRSi NCOA6. mouse.
NextBioi 35543896.
SOURCEi Search...

Gene expression databases

ArrayExpressi A2AQM9.

Family and domain databases

InterProi IPR026638. NCOA6.
[Graphical view ]
PANTHERi PTHR15690. PTHR15690. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AQM9_MOUSE
AccessioniPrimary (citable) accession number: A2AQM9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: May 14, 2014
Last modified: September 3, 2014
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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