Protein Duox1 - Mus musculus (Mouse)

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A2AQ92 (A2AQ92_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 66. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Protein Duox1 Ensembl ENSMUSP00000097060

Gene names

Name:

Duox1 Ensembl ENSMUSP00000097060 MGI 2139422

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000097060

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1551 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 FAD-binding FR-type domain. SAAS SAAS013121

Contains 1 ferric oxidoreductase domain. SAAS SAAS017927

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000097060

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS017927
Molecular function	Oxidoreductase SAAS SAAS013121
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cuticle development Inferred from electronic annotation. Source: Compara cytokine-mediated signaling pathway Inferred from electronic annotation. Source: Compara reactive oxygen species metabolic process Inferred from genetic interaction PubMed 20233719. Source: MGI response to oxidative stress Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from direct assay PubMed 20233719. Source: MGI
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A2AQ92 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 8B9729E2F23CAF1E
Show »

FASTA

1,551

177,132

        10         20         30         40         50         60 
MGFHLALAWI LLVGTLASLG AQNSISWEVQ RFDGWYNNLM EHRWGSKGSR LQRLVPASYA 

        70         80         90        100        110        120 
DGVYQPLKEP YLPNPRHLSN RVMRGSAGQP SLRNRTVLGV FFGYHVLSDL VSVETPGCPA 

       130        140        150        160        170        180 
EFLNIYIPHG DPVFDPDKRG NVVLPFQRSR WDRNTGQSPS NPRDQSNQVT GWLDGSAIYG 

       190        200        210        220        230        240 
SSHSWSDTLR SFSGGQLASG PDPAFPSDSQ SSLLMWMAPD PSTGQGGPRG VYAFGAQRGN 

       250        260        270        280        290        300 
REPFLQALGL LWFRYHNLCA RKLAQEHPHW GDEELFQHAR KRVIATYQNI AMYEWLPSFL 

       310        320        330        340        350        360 
KQTPPEYPGY RPFLDPSISP EFVVASEQFL STMVPSGVYM RNASCHFQGI PSHNSSVSGA 

       370        380        390        400        410        420 
LRVCNSYWSR EHPKLQRAED VDALLLGMAS QIAEREDHVV VEDMQDFWPG PLKFSRTDYL 

       430        440        450        460        470        480 
ASCLQRGRDL GLPSYTKARE ALGLSPISHW QDINPALSRS NGTVLEATAA LYNQDLSRLE 

       490        500        510        520        530        540 
LLPGGLLESH GDPGPLFSTI VLDQFVRLRD GDRYWFENTR NGLFSKEEIA EIRNTSLRDI 

       550        560        570        580        590        600 
LVAVTNVDPS ALQPNVFFWL AGDPCPQPSQ LSAKGLPACA PLFIRDYFEG SGFGFGLTIG 

       610        620        630        640        650        660 
TLCCFPLVSL LSAWIVARLR KRNFKRLQRQ DRQSIMSEKL VGGVEALEWQ GRNEPCRPVL 

       670        680        690        700        710        720 
VHLQPGQIRV VDGRLTVLRT IQLRPPQQVN LILSSNRGRR TLLLKIPKEY DLVLLFNMEE 

       730        740        750        760        770        780 
ERQALVENVR GALKENGLSF QEWELREQEL MRAAVTRQQR GHLLETFFRH LFSQVLDINQ 

       790        800        810        820        830        840 
ADAGTLPLDS STKVREALTC ELSRAEFADS LGLKPQDMFV ESMFSLADKD GNGYLSFREF 

       850        860        870        880        890        900 
LDILVVFMKG SPEEKSRLMF RMYDFDGNGL ISKDEFIRML RSFIEISNNC LSKAQLAEVV 

       910        920        930        940        950        960 
ESMFRESGFQ DKEELTWEDF HFMLRDHDSD LRFTQLCVKG VEVPEVIKNL CRRASYISQE 

       970        980        990       1000       1010       1020 
KICPSPRMSA HCARNNMKTA SSPQRLQCPM DTDPPQEIRR RFGKKVTSFQ PLLFTEAHRE 

      1030       1040       1050       1060       1070       1080 
KFQRSRRHQT VQQFKRFIEN YRRHIGCVAV FYTITGALFL ERAYYYAFAA HHSGITDTTR 

      1090       1100       1110       1120       1130       1140 
VGIILSRGTA ASISFMFSYI LLTMCRNLIT FLRETFLNRY IPFDAAVDFH RLIASTAIIL 

      1150       1160       1170       1180       1190       1200 
TVLHSAGHVV NVYLFSISPL SVLSCLFPGL FHDDGSEFPQ KYYWWFFQTV PGLTGVLLLL 

      1210       1220       1230       1240       1250       1260 
ALAIMYVFAS HHFRRRSFRG FWLTHHLYIF LYILLIIHGS FALIQMPRFH IFFLVPAIIY 

      1270       1280       1290       1300       1310       1320 
VGDKLVSLSR KKVEISVVKA ELLPSGVTHL RFQRPQGFEY KSGQWVRIAC LALGTTEYHP 

      1330       1340       1350       1360       1370       1380 
FTLTSAPHED TLSLHIRAAG PWTTRLREIY SPPTGDTCAR YPKLYLDGPF GEGHQEWHKF 

      1390       1400       1410       1420       1430       1440 
EVSVLVGGGI GVTPFASILK DLVFKSSVSC QVFCKKIYFI WVTRTQRQFE WLADIIREVE 

      1450       1460       1470       1480       1490       1500 
ENDRQDLVSV HIYITQLAEK FDLRTTMLYI CERHFQKVLN RSLFTGLRSI THFGRPPFEP 

      1510       1520       1530       1540       1550 
FFNSLQEVHP QVRKIGVFSC GPPGMTKNVE KACQLINRQD RTHFSHHYEN F

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000097060.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000097060.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL844566 Genomic DNA. No translation available.
IPI	IPI00663876.
RefSeq	NP_001092767.1. NM_001099297.1.
UniGene	Mm.108582.
3D structure databases
ProteinModelPortal	A2AQ92.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000097060.
Proteomic databases
PaxDb	A2AQ92.
PRIDE	A2AQ92.
Protocols and materials databases
DNASU	99439.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000099461; ENSMUSP00000097060; ENSMUSG00000033268.
GeneID	99439.
KEGG	mmu:99439.
UCSC	uc008map.1. mouse.
Organism-specific databases
CTD	53905.
MGI	MGI:2139422. Duox1.
Phylogenomic databases
eggNOG	COG5126.
GeneTree	ENSGT00550000074350.
HOGENOM	HOG000231774.
HOVERGEN	HBG080428.
InParanoid	A2AQ92.
KO	K13411.
OMA	HRRHIGC.
OrthoDB	EOG4VQ9ND.
Family and domain databases
Gene3D	1.10.238.10. 1 hit. 1.10.640.10. 1 hit.
InterPro	IPR011992. EF-hand-like_dom. IPR018247. EF_Hand_1_Ca_BS. IPR002048. EF_hand_dom. IPR013112. FAD-bd_8. IPR017927. Fd_Rdtase_FAD-bd. IPR013130. Fe3_Rdtase_TM_dom. IPR013121. Fe_red_NAD-bd_6. IPR010255. Haem_peroxidase. IPR002007. Haem_peroxidase_animal. IPR019791. Haem_peroxidase_animal_subgr. IPR017938. Riboflavin_synthase-like_b-brl. [Graphical view]
Pfam	PF03098. An_peroxidase. 1 hit. PF13499. EF_hand_5. 1 hit. PF08022. FAD_binding_8. 1 hit. PF01794. Ferric_reduct. 1 hit. PF08030. NAD_binding_6. 1 hit. [Graphical view]
PRINTS	PR00457. ANPEROXIDASE.
SMART	SM00054. EFh. 2 hits. [Graphical view]
SUPFAM	SSF48113. Peroxidase_super. 1 hit. SSF63380. Riboflavin_synthase_like_b-brl. 1 hit.
PROSITE	PS00018. EF_HAND_1. 2 hits. PS50222. EF_HAND_2. 3 hits. PS51384. FAD_FR. 1 hit. PS50292. PEROXIDASE_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	353935.
SOURCE	Search...

Entry information

Entry name

A2AQ92_MOUSE

Accession

Primary (citable) accession number: A2AQ92

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Other

Entry information