A2APF7 (A2APF7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Z-DNA-binding protein 1 Ensembl ENSMUSP00000029018

Gene names

Name:

Zbp1 Ensembl ENSMUSP00000029018 MGI 1927449

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000029018

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000029018

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	positive regulation of type I interferon-mediated signaling pathway Inferred from mutant phenotype PubMed 17618271. Source: MGI
Cellular_component	cytoplasm Inferred from sequence orthology PubMed 19158679. Source: MGI cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from sequence orthology PubMed 19158679. Source: MGI
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro double-stranded RNA adenosine deaminase activity Inferred from electronic annotation. Source: InterPro left-handed Z-DNA binding Inferred from direct assay PubMed 11524677. Source: MGI
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
CTBP1	Q13363	2	EBI-6115394,EBI-908846	From a different organism.
CTBP2	P56545	2	EBI-6115394,EBI-741533	From a different organism.
PALD1	Q9ULE6	2	EBI-6115394,EBI-3957166	From a different organism.
PLXDC2	Q6UX71	2	EBI-6115394,EBI-6115410	From a different organism.
TRAF3	Q13114	2	EBI-6115394,EBI-357631	From a different organism.

Sequences

	Sequence		Length	Mass (Da)
	A2APF7 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 985F7B527F7DA5EA	FASTA	411	44,271
	10 20 30 40 50 60 MAEAPVDLST GDNLEQKILQ VLSDDGGPVK IGQLVKKCQV PKKTLNQVLY RLKKEDRVSS 70 80 90 100 110 120 PEPATWSIGG AASGDGAPAI PENSSAQPSL DERILRFLEA NGPHRALHIA KALGMTTAKE 130 140 150 160 170 180 VNPLLYSMRN KHLLSYDGQT WKIYHSRQEG QDIAHSGVTQ ESPAIICQHN PVNMICQQGA 190 200 210 220 230 240 NSHISIANSN AIQIGHGNVI VREKACGEPG PRTSHPLPLA WDASAQDMPP VAHGAQYIYM 250 260 270 280 290 300 DKSLLQQVQL GHHNEMSLVG DAGKHPSYSF SDSPPEVSTT TADPGASFNM QTSEPGPHPE 310 320 330 340 350 360 GDTVQTVHIK SCFLEDATIG NGNKMTIHLR SKGEVMESGD SEEPKKEDTG TSSEATPPRS 370 380 390 400 410 CQHTPSDSML PTSELRAMAL GDSSPQTTEP VLREHEVQDI ESSQDTGLSK Q

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000029018.
[2]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000029018.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL837509 Genomic DNA. No translation available.
IPI	IPI00915524.
RefSeq	NP_067369.2. NM_021394.2.
UniGene	Mm.116687.
3D structure databases
ProteinModelPortal	A2APF7.
SMR	A2APF7. Positions 13-69, 91-144.
ModBase	Search...
Protein-protein interaction databases
IntAct	A2APF7. 9 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000029018; ENSMUSP00000029018; ENSMUSG00000027514.
GeneID	58203.
KEGG	mmu:58203.
UCSC	uc008odo.2. mouse.
Organism-specific databases
CTD	81030.
MGI	MGI:1927449. Zbp1.
Phylogenomic databases
GeneTree	ENSGT00390000002234.
HOVERGEN	HBG036279.
InParanoid	A2APF7.
KO	K12965.
OMA	SHFPRDI.
Gene expression databases
ArrayExpress	A2APF7.
Family and domain databases
Gene3D	1.10.10.10. 2 hits.
InterPro	IPR000607. dsRNA_A_deaminase. IPR025735. RHIM_dom. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF12721. RHIM. 3 hits. PF02295. z-alpha. 2 hits. [Graphical view]
SMART	SM00550. Zalpha. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	314185.
SOURCE	Search...

Entry information

Entry name

A2APF7_MOUSE

Accession

Primary (citable) accession number: A2APF7

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)