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A2APF7

- A2APF7_MOUSE

UniProt

A2APF7 - A2APF7_MOUSE

Protein
Submitted name:

Z-DNA-binding protein 1

Gene

Zbp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. double-stranded RNA adenosine deaminase activity Source: InterPro
    3. left-handed Z-DNA binding Source: MGI
    4. protein binding Source: IntAct
    5. RNA binding Source: InterPro

    GO - Biological processi

    1. positive regulation of type I interferon-mediated signaling pathway Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Z-DNA-binding protein 1Imported
    Gene namesi
    Name:Zbp1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1927449. Zbp1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytosol Source: Ensembl
    3. nucleus Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiA2APF7.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CTBP1Q133632EBI-6115394,EBI-908846From a different organism.
    CTBP2P565452EBI-6115394,EBI-741533From a different organism.
    PALD1Q9ULE62EBI-6115394,EBI-3957166From a different organism.
    PLXDC2Q6UX712EBI-6115394,EBI-6115410From a different organism.
    TRAF3Q131142EBI-6115394,EBI-357631From a different organism.

    Protein-protein interaction databases

    IntActiA2APF7. 9 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliA2APF7.
    SMRiA2APF7. Positions 13-69, 92-144.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000002234.
    HOVERGENiHBG036279.
    InParanoidiA2APF7.
    KOiK12965.
    OMAiKECQVPK.
    OrthoDBiEOG70S75W.
    TreeFamiTF337658.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    InterProiIPR000607. dsRNA_A_deaminase.
    IPR025735. RHIM_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF12721. RHIM. 2 hits.
    PF02295. z-alpha. 2 hits.
    [Graphical view]
    SMARTiSM00550. Zalpha. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2APF7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEAPVDLST GDNLEQKILQ VLSDDGGPVK IGQLVKKCQV PKKTLNQVLY    50
    RLKKEDRVSS PEPATWSIGG AASGDGAPAI PENSSAQPSL DERILRFLEA 100
    NGPHRALHIA KALGMTTAKE VNPLLYSMRN KHLLSYDGQT WKIYHSRQEG 150
    QDIAHSGVTQ ESPAIICQHN PVNMICQQGA NSHISIANSN AIQIGHGNVI 200
    VREKACGEPG PRTSHPLPLA WDASAQDMPP VAHGAQYIYM DKSLLQQVQL 250
    GHHNEMSLVG DAGKHPSYSF SDSPPEVSTT TADPGASFNM QTSEPGPHPE 300
    GDTVQTVHIK SCFLEDATIG NGNKMTIHLR SKGEVMESGD SEEPKKEDTG 350
    TSSEATPPRS CQHTPSDSML PTSELRAMAL GDSSPQTTEP VLREHEVQDI 400
    ESSQDTGLSK Q 411
    Length:411
    Mass (Da):44,271
    Last modified:February 20, 2007 - v1
    Checksum:i985F7B527F7DA5EA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL837509 Genomic DNA. No translation available.
    RefSeqiNP_067369.2. NM_021394.2.
    UniGeneiMm.116687.

    Genome annotation databases

    EnsembliENSMUST00000029018; ENSMUSP00000029018; ENSMUSG00000027514.
    GeneIDi58203.
    KEGGimmu:58203.
    UCSCiuc008odo.3. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL837509 Genomic DNA. No translation available.
    RefSeqi NP_067369.2. NM_021394.2.
    UniGenei Mm.116687.

    3D structure databases

    ProteinModelPortali A2APF7.
    SMRi A2APF7. Positions 13-69, 92-144.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi A2APF7. 9 interactions.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000029018 ; ENSMUSP00000029018 ; ENSMUSG00000027514 .
    GeneIDi 58203.
    KEGGi mmu:58203.
    UCSCi uc008odo.3. mouse.

    Organism-specific databases

    CTDi 81030.
    MGIi MGI:1927449. Zbp1.

    Phylogenomic databases

    GeneTreei ENSGT00390000002234.
    HOVERGENi HBG036279.
    InParanoidi A2APF7.
    KOi K12965.
    OMAi KECQVPK.
    OrthoDBi EOG70S75W.
    TreeFami TF337658.

    Miscellaneous databases

    NextBioi 314185.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi A2APF7.

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    InterProi IPR000607. dsRNA_A_deaminase.
    IPR025735. RHIM_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF12721. RHIM. 2 hits.
    PF02295. z-alpha. 2 hits.
    [Graphical view ]
    SMARTi SM00550. Zalpha. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2APF7_MOUSE
    AccessioniPrimary (citable) accession number: A2APF7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3