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A2ANY6 (A2ANY6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length5589 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits By similarity. PIRNR PIRNR010340

Subcellular location

Nucleus By similarity PIRNR PIRNR010340.

Sequence similarities

Belongs to the midasin family. PIRNR PIRNR010340

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000071569

Ontologies

Keywords
   Cellular componentNucleus PIRNR PIRNR010340
   LigandATP-binding PIRNR PIRNR010340 RuleBase RU003299
Nucleotide-binding
   Molecular functionChaperone PIRNR PIRNR010340
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein complex assembly

Inferred from electronic annotation. Source: InterPro

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A2ANY6 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: CE58B46C42EA157A

FASTA5,589630,342
        10         20         30         40         50         60 
MEHLSVELVS GPLRLIAAKN EKSSGELNRF LAKSVWTPQD RQCILDSLAQ LLLDKDYTLL 

        70         80         90        100        110        120 
LGRQLRPILL DLLERNAKAI KTGGQVNHDL HERLSVSMSK LIGSHPDVLP FALRYFKDTY 

       130        140        150        160        170        180 
PVFQRLFLES SDANPVRYGR RRMKLRDLME AANIFLQHRQ TVFRELWDWS VCVPLLRSHD 

       190        200        210        220        230        240 
ALVRWHTANC LALVTCMNEE HKLSFLRKIF SSDELVHFRL RLLEEAQLQD LEKALVLANP 

       250        260        270        280        290        300 
EVSLWHKGEE PQYIQGHLVS ADLSSSVAAV CGVVLPKLSS SPGEQASDRS SSLEQELALK 

       310        320        330        340        350        360 
SFVLVESVCK NLQLLAVSVA SQNAVLLEGP IGSGKTSLVE HLAAVTGRTK PPQLLKVQLG 

       370        380        390        400        410        420 
DQTDSKMLLG MYRCTDVPGE FVWQPGTLTQ AATKGYWILL EDIDYAPLDV VSVLIPLLEH 

       430        440        450        460        470        480 
GELLIPGHGD CLKVAPTFQL FATRRLLSCG GSWYRPMNSH ATMLDKYWTK IHLHNLNKKD 

       490        500        510        520        530        540 
LNEVLQSKYP SLLAATDHLL DIYIELTGEK HCCPSVAYDK APQEVSEAER ENRRVVLEGR 

       550        560        570        580        590        600 
ELSLRDLLNW CNRVAHGFDP TSSTALLHIF QEAMDCFTAM LSEQTKKLRM AEVIGSRLNI 

       610        620        630        640        650        660 
SKKKAEFYCK LYKPEIVINE LDVQVGRVRL LRKQSEVVRI QKEKCTFAAT RPSSVLLEQL 

       670        680        690        700        710        720 
AVCVSQGEPV LLVGETGTGK TSAVQYLAYA TGQHLRVVNM NQQSDTADLL GGFKPVDHKL 

       730        740        750        760        770        780 
IWLPLRETFE ELFVQTFSKK QNFTFLGHIQ TCYRQKRWHD LLKLMLHVQK SASTKGGEQS 

       790        800        810        820        830        840 
QPGLLKEKWE AFGLRLNHAQ QQMKMTENAL LFAFVEGTLA QAIKKGEWIL LDEINLAAPE 

       850        860        870        880        890        900 
TLECLSGLLE GSSGSLVLLD RGDTEPLVRH PDFRLFACMN PATDVGKRNL PPGIRNRFTE 

       910        920        930        940        950        960 
LYVEELESKE DLQILIVDYL KGLNVSKNTV QGIVNFYTAL RKESGTKLVD GTGHRPHYSL 

       970        980        990       1000       1010       1020 
RTLCRALRFA ASNPCGSIQR SLYEGFCLGF LTQLDRASHP VVQKLICQHI ISGNVKSLLK 

      1030       1040       1050       1060       1070       1080 
QPIPEPKGGR LIQVEGYWIS VGDKEPKIDE TYVLTPSVKL NLRDIARVVS AGTYPVLIQG 

      1090       1100       1110       1120       1130       1140 
ETSVGKTSLI RWLAAASGNH CVRINNHEHT DIQEYIGCYT SDTSGKLVFN EGVLIDAMRK 

      1150       1160       1170       1180       1190       1200 
GYWIVLDELN LAPTDVLEAL NRLLDDNREL LITETQEVVR AHPRFMLFAT QNPPGLYGGR 

      1210       1220       1230       1240       1250       1260 
KVLSRAFRNR FVELHFDELP SSELETILHK RCSLPPSYCS KLVKVMLDLQ SYRRRSSVFA 

      1270       1280       1290       1300       1310       1320 
GKQGFIALRD LFRWAERYRL AEQTQEDYDW LQHLANDGFM LLAGRVRKQE EADVIQEVLE 

      1330       1340       1350       1360       1370       1380 
KHFKKKLCPQ SLFSKENVLK LLGKSSTQTT VLESKFSHVV WTESMRRLAV LVGRALEFGE 

      1390       1400       1410       1420       1430       1440 
PVLLVGDTGC GKTTVCQMFS ALANQKLYSV NCHLNMETSD FLGGLRPVRQ KPNDKDELDT 

      1450       1460       1470       1480       1490       1500 
RLFEWHDGPL VLAMKEDSFF LLDEISLADD SVLERLNSVL EVEKCLVLAE KGSPESKDNE 

      1510       1520       1530       1540       1550       1560 
VELLTAGKHF RILATMNPGG DFGKKELSPA LRNRFTEIWC PQSTKREDLI QIINHNLRPG 

      1570       1580       1590       1600       1610       1620 
LSLAGVGHKG AGVAEVMLAF ITWLTRQEFG RKCVVSIRDI LSWVNFMNSM AEDAAVKRPE 

      1630       1640       1650       1660       1670       1680 
AISTVTSFVH AACLVYIDGI GSGVTSSGFG TALLAREECL KFLIKKLSKV VRLTQRQKDE 

      1690       1700       1710       1720       1730       1740 
LKIYDRLRHK EFTSIDDFWG VHPFFIPRGP VLDGHNTGDY ALTAGTTAMN AQRLLRAAKL 

      1750       1760       1770       1780       1790       1800 
NKPILLEGSP GVGKTSLVAA LAKASGNTLV RINLSEQTDI TDLFGADLPV EGGRGGEFAW 

      1810       1820       1830       1840       1850       1860 
CDGPLLAALK AGHWVVLDEL NLASQSILEG LNACFDHRGE IYVPELGMSF QVQHEKTRIF 

      1870       1880       1890       1900       1910       1920 
GCQNPFRQGG GRKGLPKSFL NRFTQVFVDP LTVVDMEFIA STLFPTIDKD IVKKMVAFNN 

      1930       1940       1950       1960       1970       1980 
HIDHEVTVEK KWGQKGGPWE FNLRDLFRWC QLILVDQSPG CYDPGQHVFL VYGERMRTRE 

      1990       2000       2010       2020       2030       2040 
DKEKVVAVFK DVFASNSMPY IGTRQFHITP YDIQIGYSVL SRSSYVPHPS RRPLSLLHQS 

      2050       2060       2070       2080       2090       2100 
FQSLEPIMKC VQMNWMVILV GPASVGKTSL VQLLAHLTGH TLKIMAMNSA MDTTELLGGF 

      2110       2120       2130       2140       2150       2160 
EQVDIIRPWR LLLEKVERTV RVLLRDSLLI NSVDTEVVLQ AWSHFLLTYK PKCLGEDGKG 

      2170       2180       2190       2200       2210       2220 
VTIEIVNKLE AVLLLMQRLN NKINSYSKAD FAKLVEDFRS FGVKLLQSAS GRSHGSFEWV 

      2230       2240       2250       2260       2270       2280 
DSMLVQALKS GDWLLMDNVN FCNPSVLDRL NALLEPGGVL TINERGMVDG STCTVTPNPN 

      2290       2300       2310       2320       2330       2340 
FRLFLSMDPI HGEISRAMRN RGLEIYISGE EDGSIQDNLD LKVLLHSLGL VGDSVCNILL 

      2350       2360       2370       2380       2390       2400 
ALHTEIQSLV RGSPASSVST LSHTAILIVQ YLQRGLSLHK AFFEACWEVY VCSQHSAANQ 

      2410       2420       2430       2440       2450       2460 
KLVQDLLESH TASLQARETW GHSILATGLW PDSVPSALFA TEDSRLSVVR SEGQILAYCL 

      2470       2480       2490       2500       2510       2520 
NRMSLKTSSW TRSQPLTLQD LENIMQTCSP DDLTFNAVEV DTCWVDEPEV LATAVKLLIE 

      2530       2540       2550       2560       2570       2580 
RATNQDWMLR VKWLCHLAKN IPQGLESVRV HLEASATALR KFYSTSLSAG VSNVLKILQT 

      2590       2600       2610       2620       2630       2640 
NITDDFVIPL DPRWNMQALD IIRNSLDFDP QSDQAKQLFA LLESVANKTF IYLDREKRIF 

      2650       2660       2670       2680       2690       2700 
TEANLVSVGS KKLRSSVLRM SFEFHKDPEN YHSPPHEIVA NLAAFFELID GLILLWVQSP 

      2710       2720       2730       2740       2750       2760 
QGVVPDAHIN KILGSVQWRD RFWTVADTVT VDASGLALLA LHWHWVSKHL IYQIPQLLVN 

      2770       2780       2790       2800       2810       2820 
QENKYYKELQ TVSEHIHSCL GSPADSFAGV KKLQAFLGRP FPFKDKLVVD CFLQLQALNR 

      2830       2840       2850       2860       2870       2880 
ALAIGEQLPV FGECGWQEDI NRLQVVASEW NLKKSLLQAW GLILRANILE DVNLDELKNL 

      2890       2900       2910       2920       2930       2940 
VSTQCSELKS RGLSRGFLEK AHDASSPSQP DLSSLVHLTR RVQLWPAAEY LAMLWQYRVT 

      2950       2960       2970       2980       2990       3000 
ADFIAQACLR RSSKHDQMDE EISHHIAFCL KHTPIAPQKL WNLWSLLHIE MLSAQEVSCL 

      3010       3020       3030       3040       3050       3060 
WSELFTSTFG SSWSSPVTTA PECWLAWSPL PNIQQQEVPR SRWDSTLKGP GSLCRAVFSK 

      3070       3080       3090       3100       3110       3120 
CCFGVLTNSS RASYWDVSGL PLLSSSHVTL GEWVERAQQL QDISSLLWTN MAVPSVAEFR 

      3130       3140       3150       3160       3170       3180 
RTDSRLQGLV LCRYLLGLTE LLPAHQRQEY MQNCEHLLLG NTQAFHHVDQ TMGNIGGQEA 

      3190       3200       3210       3220       3230       3240 
LPKELLCLLL TSLHYFIGEG EGKQNLPEAA RRGRLWVSLG LLQIQTWLPR ARFDPAVKKA 

      3250       3260       3270       3280       3290       3300 
YKLRYAQDEL RQLQCELKTR NLLSHLQTGR DLEDDIITSH SHPHIKLLPQ RISQLESLVH 

      3310       3320       3330       3340       3350       3360 
SLSKKQAFRP HLPSYETLVQ EIHHYVTSIA KVTAVQDLLM RLLQALHTDG PKSAQVLQNL 

      3370       3380       3390       3400       3410       3420 
LKEEASWQQS HHQFRKRLVE EYALYPDTVA PLLASILQLQ HGMRLVASEV HASLHSGVLC 

      3430       3440       3450       3460       3470       3480 
AENLGALAMA VLAFPSVGPS FPTYHAHADA LCSVNAAEAL RSLGKLMVKR AARKEEAKSQ 

      3490       3500       3510       3520       3530       3540 
QAYPTREQLL MNALLYLRSH VLCKGELDQR ALLLFRHLCQ EIINEWDEQE RIAQEKAEQE 

      3550       3560       3570       3580       3590       3600 
SSLYRYRSRS GRTALSEEEE EELELRKLFP LHEKDFADIL MEPTLEEKKK VSDGREEEAA 

      3610       3620       3630       3640       3650       3660 
PDPTLLCQSS MQAVMLIHQQ LCLSFARSLW YQQAVPPHEA KHYLSLFLSC YQTGASLVTH 

      3670       3680       3690       3700       3710       3720 
FYPLMGVELN DQLLGSQLLA CTLSSNTLCG EATSDLMMRP DGPYDFYQHP NVAEARQCQP 

      3730       3740       3750       3760       3770       3780 
VLQGFSEAVS QLLQDWPEHP VLQQLLVVMD RIRGFPLSSP ISKFLNGLEI LLAKAQDWEE 

      3790       3800       3810       3820       3830       3840 
NASRVLSLRK HLDLVSQMII RWRKLELNCW SMSLDNTMIR HTEKSTKHWF SIYQMLEKHM 

      3850       3860       3870       3880       3890       3900 
QERTEEQEDD KQMTLMLLVS TLQAFIEGSS LGEFHVRLQM LLVFHCHVLL MPQVEGKDSL 

      3910       3920       3930       3940       3950       3960 
CSVLWNLYHF YKQFLDPVKA KIMELRSPIE KELKEFVKIS KWNDVSFWSI KQSVEKTHRT 

      3970       3980       3990       4000       4010       4020 
LFKFMKKFEA VLSEPCQSCL VESDKEEQPD CLPKPTEEAT METSPIQGLN NALRETLLAQ 

      4030       4040       4050       4060       4070       4080 
PVEWKPSGTE QCQDASPLSV EGELLRRLPR LSKRMRKMCL VFMKESPLPH LVESLDQFTG 

      4090       4100       4110       4120       4130       4140 
GVISSVSELQ SLKVDPSAEK EKQHSEAKHI LLQKHRALSD LFKHLANIGL SYRKGLAWAR 

      4150       4160       4170       4180       4190       4200 
SKSPQELLHL HPLDLRSALS IVSSTREADS RLLTEISSLW DGCQKYFYRS LARHTRLTAA 

      4210       4220       4230       4240       4250       4260 
LATPVKEVSM GTIERCKGFS AHLMKLLIRQ RHSLTTLTEQ WIILRNLLSC VQEIHSRLTG 

      4270       4280       4290       4300       4310       4320 
PPVYPVAFPP QDSVQQWTER LQHLAMQSQI LLEQFSWLFQ CCPSAEPTVG HRDAQVQEHP 

      4330       4340       4350       4360       4370       4380 
SASHLENIDF KETIAGVMPD LLSSDLSYPS PVPTSQLPSA CRMRRQDQLW QQSTAGLTEM 

      4390       4400       4410       4420       4430       4440 
LKTIKTMKAG VDKIRQQSCE TLFHTWEDFE VCSSGLNCLS QVSAHLQGLA SLFILPGIEV 

      4450       4460       4470       4480       4490       4500 
EQTDSRMALV ESLDYLRGEV SKAIDDFTAW KARLFVAHKQ EGNQMVEESF VEDFSEQVET 

      4510       4520       4530       4540       4550       4560 
AIRAILCTIQ NLAERNNKKA EDSAVDKRLQ EEDGGKEEEA SFKSLQPGHL TKLLEDDFWA 

      4570       4580       4590       4600       4610       4620 
SVSTLHVQKI ISSVSELLER LKSCSEDGNT TKHKVFSQSC GLLVRLIPIL CGFSDLVLFF 

      4630       4640       4650       4660       4670       4680 
LTVSLATHRS TAKLLSVLAQ TFTELSQKGF CLPKELMEDS AGEGATQFHD YEGGGIGDGE 

      4690       4700       4710       4720       4730       4740 
GMKDVSDRIE NEEQVEDTFQ KGQEKDEEDL DSKPDTKGED NAIEMSEDFD GKMHDGELEQ 

      4750       4760       4770       4780       4790       4800 
EEDDEKSDSE DGDLDKQMGN LNGEEADKLD ERLWGDDEEE DEDGDGRAEE TGPGVDEEDS 

      4810       4820       4830       4840       4850       4860 
ELVAKDDSLD AGNLNKNKKH QDEKEDSEPE DVEQGQEKIN EQIDEREYDE NEVDPYHGNQ 

      4870       4880       4890       4900       4910       4920 
EKLPEPEALD LPDDLKLDSE DKSGGEDTDN EEAEEENPLE IKEKTVDMEE TDHEIEEPGA 

      4930       4940       4950       4960       4970       4980 
GQDEGESPHE PEEGPSEDKE NMDMDTGADD QDRDTSSHAE EHSLEEEAEE EEEKGEKEED 

      4990       5000       5010       5020       5030       5040 
KATTDGGGES GVNPVDQGLQ PQKEEEEEGE QSDAEEQVPE ATERKEHATC GQTGVDNVQS 

      5050       5060       5070       5080       5090       5100 
AQAVELAGAA PEKEQGKEEH GSGAADANQA EGHESNLIAR LSSQQHTNKN TQSFKRRPGQ 

      5110       5120       5130       5140       5150       5160 
ADNERSVGDY NERVRKRLRT VGTDRETEQE PTQAQVEDAD AFEHVKQGSD AYDAQTYDVA 

      5170       5180       5190       5200       5210       5220 
SSEQQQTAKA SGQDQEEEEI EDILMDTEEE LMRAEDTEQL KPEAVQSETA ATSGSSEMEV 

      5230       5240       5250       5260       5270       5280 
DMQTLKTKED QDPRTTTPHQ ETENERPERS RDSTIHTLRQ FLVDSVFQPI LKDISELRQE 

      5290       5300       5310       5320       5330       5340 
MERQLETWQA HDYGNAEEEK AAAEMWQNYL VLTASLSQQL CEQLRLLLEP TQAAKLRGDY 

      5350       5360       5370       5380       5390       5400 
RTGKRLNMRK IIPYIASQFR KDRIWLRRTK PSKRQYQICL AIDDSSSMVD NHTKQLAFES 

      5410       5420       5430       5440       5450       5460 
LAVIGNALTL LEVGQIAVCS FGESVKLLHP FHEQFNDSSG THILRLCTFQ QRKTKIAQFL 

      5470       5480       5490       5500       5510       5520 
ETVAKMFAAA QKLSQNVSPE TAQLLLIVSD GRGLFLEGKD RVLAAVQAAQ NANIFVIFVV 

      5530       5540       5550       5560       5570       5580 
LDNPNSRDSI LDIKVPIFKG PGEMPEIRSY MEEFPFPFYI ILRDVNALPE TLSDALRQWF 


ELVTASDHS 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL805973 Genomic DNA. No translation available.
AL831774 Genomic DNA. No translation available.
RefSeqXP_006537539.1. XM_006537476.1.
UniGeneMm.24627.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

MaxQBA2ANY6.
PaxDbA2ANY6.
PRIDEA2ANY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000071642; ENSMUSP00000071569; ENSMUSG00000058006.
GeneID100019.
KEGGmmu:100019.
UCSCuc008sfa.1. mouse.

Organism-specific databases

CTD23195.
MGIMGI:1926159. Mdn1.

Phylogenomic databases

eggNOGCOG5271.
GeneTreeENSGT00550000074802.
HOGENOMHOG000231719.
HOVERGENHBG031706.
InParanoidA2ANY6.
KOK14572.
OMARIFLTMD.
OrthoDBEOG7S4X6J.
PhylomeDBA2ANY6.
TreeFamTF300488.

Gene expression databases

ArrayExpressA2ANY6.

Family and domain databases

Gene3D3.40.50.300. 8 hits.
InterProIPR003593. AAA+_ATPase.
IPR011704. ATPase_dyneun-rel_AAA.
IPR012099. Midasin.
IPR027417. P-loop_NTPase.
IPR002035. VWF_A.
[Graphical view]
PfamPF07728. AAA_5. 8 hits.
[Graphical view]
PIRSFPIRSF010340. Midasin. 1 hit.
SMARTSM00382. AAA. 5 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 8 hits.
SSF53300. SSF53300. 1 hit.
PROSITEPS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSMDN1. mouse.
NextBio35543779.
PROA2ANY6.
SOURCESearch...

Entry information

Entry nameA2ANY6_MOUSE
AccessionPrimary (citable) accession number: A2ANY6
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)