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A2AMQ5

- A2AMQ5_MOUSE

UniProt

A2AMQ5 - A2AMQ5_MOUSE

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Protein

Phosphatidate cytidylyltransferase

Gene

Cds2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferaseUniRule annotation (EC:2.7.7.41UniRule annotation)
Gene namesi
Name:Cds2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:1332236. Cds2.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA2AMQ5.

Expressioni

Gene expression databases

ExpressionAtlasiA2AMQ5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA2AMQ5.
SMRiA2AMQ5. Positions 56-366.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000016175.
HOGENOMiHOG000209582.
HOVERGENiHBG002485.

Family and domain databases

InterProiIPR000374. PC_trans.
IPR016720. PC_Trfase_euk.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF018269. PC_trans_euk. 1 hit.
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2AMQ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESESEAKLD GETASDSESR AETAPLPTSV DDTPEVLNRA LSNLSSRWKN
60 70 80 90 100
WWVRGILTLA MIAFFFIIIY LGPMVLMMIV MCVQIKCFHE IITIGYNVYH
110 120 130 140 150
SYDLPWFRTL SWYFLLCVNY FFYGETVTDY FFTLVQREEP LRILSKYHRF
160 170 180 190 200
ISFALYLTGF CMFVLSLVKK HYRLQFYMFG WTHVTLLIVV TQSHLVIHNL
210 220 230 240 250
FEGMIWFIVP ISCVICNDIM AYMFGFFFGR TPLIKLSPKK TWEGFIGGFF
260 270 280 290 300
ATVVFGLLLS YVMSGYRCFV CPVEYNNDTN SFTVDCEPSD LFRLQEYNIP
310 320 330 340 350
GVIQSAIGWK TVRMYPFQIH SIALSTFASL IGPFGGFFAS GFKRAFKIKD
360 370 380 390 400
FANTIPGHGG IMDRFDCQYL MATFVNVYIA SFIRGPNPSK LIQQFLTLRP
410 420
DQQLHIFNTL KSHLTDKGIL TSALEDE
Length:427
Mass (Da):49,294
Last modified:February 20, 2007 - v1
Checksum:iF67EF48633FAF3E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL807793 Genomic DNA. No translation available.
RefSeqiNP_001277968.1. NM_001291039.1.
UniGeneiMm.284503.

Genome annotation databases

EnsembliENSMUST00000089461; ENSMUSP00000086886; ENSMUSG00000058793.
GeneIDi110911.
UCSCiuc029ueu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL807793 Genomic DNA. No translation available.
RefSeqi NP_001277968.1. NM_001291039.1.
UniGenei Mm.284503.

3D structure databases

ProteinModelPortali A2AMQ5.
SMRi A2AMQ5. Positions 56-366.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A2AMQ5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000089461 ; ENSMUSP00000086886 ; ENSMUSG00000058793 .
GeneIDi 110911.
UCSCi uc029ueu.1. mouse.

Organism-specific databases

CTDi 8760.
MGIi MGI:1332236. Cds2.

Phylogenomic databases

GeneTreei ENSGT00390000016175.
HOGENOMi HOG000209582.
HOVERGENi HBG002485.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .

Miscellaneous databases

NextBioi 35543703.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi A2AMQ5. baseline and differential.

Family and domain databases

InterProi IPR000374. PC_trans.
IPR016720. PC_Trfase_euk.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF018269. PC_trans_euk. 1 hit.
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
    Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
    J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AMQ5_MOUSE
AccessioniPrimary (citable) accession number: A2AMQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3