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Protein
Submitted name:

Transcription factor SOX-3

Gene

Sox3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-3769402. Deactivation of the beta-catenin transactivating complex.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor SOX-3Imported
Gene namesi
Name:Sox3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:98365. Sox3.

PTM / Processingi

Proteomic databases

MaxQBiA2AM37.
PaxDbiA2AM37.
PeptideAtlasiA2AM37.

Expressioni

Gene expression databases

BgeeiENSMUSG00000045179.
GenevisibleiA2AM37. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000115237.

Structurei

3D structure databases

ProteinModelPortaliA2AM37.
SMRiA2AM37.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 212HMG box DNA-bindingInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG4111FVF. LUCA.
GeneTreeiENSGT00760000118988.
HOGENOMiHOG000231647.
HOVERGENiHBG105663.
KOiK09267.
OMAiALPPMHR.
OrthoDBiEOG091G0F15.
PhylomeDBiA2AM37.
TreeFamiTF351735.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
IPR029550. SOX-3.
IPR022097. SOX_fam.
[Graphical view]
PANTHERiPTHR10270:SF111. PTHR10270:SF111. 2 hits.
PfamiPF00505. HMG_box. 1 hit.
PF12336. SOXp. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2AM37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPARENASG ERSPRVPADF ARSPSASLPF PPELPARRPL STTPTESPGL
60 70 80 90 100
FTVAAPAPGA PSPPATLAHL LPAPAMYSLL ETELKNPVGP PTPAAGTGVP
110 120 130 140 150
AAPGAAGKSG ANPAGGANAG NGGSGGANGG GGGGGGGGSD QDRVKRPMNA
160 170 180 190 200
FMVWSRGQRR KMALENPKMH NSEISKRLGA DWKLLTDAEK RPFIDEAKRL
210 220 230 240 250
RAVHMKEYPD YKYRPRRKTK TLLKKDKYSL PGGLLPPGAA AAAAAAAAAA
260 270 280 290 300
AASSPVGVGQ RLDTYTHVNG WANGAYSLVQ EQLGYAQPPS MSSPPPPPAL
310 320 330 340 350
PQMHRYDMAG LQYSPMMPPG AQSYMNAAAA AAAASGYGGM APSAAAAAAA
360 370 380 390 400
AYGQQPATAA AAAAAAAAMS LGPMGSVVKS EPSSPPPAIA SHSQRACLGD
410 420 430 440 450
LRDMISMYLP PGGDAADAAS PLPGGRLHGV HQHYQGAGTA VNGTVPLTHI
Length:450
Mass (Da):45,444
Last modified:March 3, 2009 - v1
Checksum:iD43522C2E9162CAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807233 Genomic DNA. No translation available.
RefSeqiNP_033263.2. NM_009237.2.
UniGeneiMm.35784.

Genome annotation databases

EnsembliENSMUST00000135107; ENSMUSP00000115237; ENSMUSG00000045179.
GeneIDi20675.
KEGGimmu:20675.
UCSCiuc009vff.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807233 Genomic DNA. No translation available.
RefSeqiNP_033263.2. NM_009237.2.
UniGeneiMm.35784.

3D structure databases

ProteinModelPortaliA2AM37.
SMRiA2AM37.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000115237.

Proteomic databases

MaxQBiA2AM37.
PaxDbiA2AM37.
PeptideAtlasiA2AM37.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000135107; ENSMUSP00000115237; ENSMUSG00000045179.
GeneIDi20675.
KEGGimmu:20675.
UCSCiuc009vff.1. mouse.

Organism-specific databases

CTDi6658.
MGIiMGI:98365. Sox3.

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG4111FVF. LUCA.
GeneTreeiENSGT00760000118988.
HOGENOMiHOG000231647.
HOVERGENiHBG105663.
KOiK09267.
OMAiALPPMHR.
OrthoDBiEOG091G0F15.
PhylomeDBiA2AM37.
TreeFamiTF351735.

Enzyme and pathway databases

ReactomeiR-MMU-3769402. Deactivation of the beta-catenin transactivating complex.

Miscellaneous databases

ChiTaRSiSox3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045179.
GenevisibleiA2AM37. MM.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
IPR029550. SOX-3.
IPR022097. SOX_fam.
[Graphical view]
PANTHERiPTHR10270:SF111. PTHR10270:SF111. 2 hits.
PfamiPF00505. HMG_box. 1 hit.
PF12336. SOXp. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA2AM37_MOUSE
AccessioniPrimary (citable) accession number: A2AM37
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.