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Protein
Submitted name:

Transcription factor SOX-3

Gene

Sox3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi144 – 212HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-3769402. Deactivation of the beta-catenin transactivating complex.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor SOX-3Imported
Gene namesi
Name:Sox3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:98365. Sox3.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

MaxQBiA2AM37.
PaxDbiA2AM37.
PeptideAtlasiA2AM37.

Expressioni

Gene expression databases

BgeeiENSMUSG00000045179.
GenevisibleiA2AM37. MM.

Structurei

3D structure databases

ProteinModelPortaliA2AM37.
SMRiA2AM37.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 212HMG box DNA-bindingInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG4111FVF. LUCA.
GeneTreeiENSGT00760000118988.
HOGENOMiHOG000231647.
HOVERGENiHBG105663.
KOiK09267.
OMAiHQHYQSA.
OrthoDBiEOG091G0F15.
PhylomeDBiA2AM37.
TreeFamiTF351735.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR009071. HMG_box_dom.
IPR022097. SOX_fam.
PfamiView protein in Pfam
PF00505. HMG_box. 1 hit.
PF12336. SOXp. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AM37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPARENASG ERSPRVPADF ARSPSASLPF PPELPARRPL STTPTESPGL
60 70 80 90 100
FTVAAPAPGA PSPPATLAHL LPAPAMYSLL ETELKNPVGP PTPAAGTGVP
110 120 130 140 150
AAPGAAGKSG ANPAGGANAG NGGSGGANGG GGGGGGGGSD QDRVKRPMNA
160 170 180 190 200
FMVWSRGQRR KMALENPKMH NSEISKRLGA DWKLLTDAEK RPFIDEAKRL
210 220 230 240 250
RAVHMKEYPD YKYRPRRKTK TLLKKDKYSL PGGLLPPGAA AAAAAAAAAA
260 270 280 290 300
AASSPVGVGQ RLDTYTHVNG WANGAYSLVQ EQLGYAQPPS MSSPPPPPAL
310 320 330 340 350
PQMHRYDMAG LQYSPMMPPG AQSYMNAAAA AAAASGYGGM APSAAAAAAA
360 370 380 390 400
AYGQQPATAA AAAAAAAAMS LGPMGSVVKS EPSSPPPAIA SHSQRACLGD
410 420 430 440 450
LRDMISMYLP PGGDAADAAS PLPGGRLHGV HQHYQGAGTA VNGTVPLTHI
Length:450
Mass (Da):45,444
Last modified:March 3, 2009 - v1
Checksum:iD43522C2E9162CAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807233 Genomic DNA. No translation available.
RefSeqiNP_033263.2. NM_009237.2.
UniGeneiMm.35784.

Genome annotation databases

EnsembliENSMUST00000135107; ENSMUSP00000115237; ENSMUSG00000045179.
GeneIDi20675.
KEGGimmu:20675.
UCSCiuc009vff.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA2AM37_MOUSE
AccessioniPrimary (citable) accession number: A2AM37
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 5, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported