Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Paired box protein Pax-1

Gene

Pax1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  • bone morphogenesis Source: MGI
  • CD4-positive, alpha-beta T cell differentiation Source: MGI
  • CD8-positive, alpha-beta T cell differentiation Source: MGI
  • cell proliferation Source: MGI
  • organ morphogenesis Source: MGI
  • parathyroid gland development Source: MGI
  • pattern specification process Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • regulation of transcription, DNA-templated Source: MGI
  • skeletal system development Source: MGI
  • somitogenesis Source: MGI
  • thymus development Source: MGI
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-1Imported
Gene namesi
Name:Pax1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:97485. Pax1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  • nucleus Source: UniProtKB-SubCell
  • transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiA2ALK0.
ExpressionAtlasiA2ALK0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105594.

Structurei

3D structure databases

ProteinModelPortaliA2ALK0.
SMRiA2ALK0. Positions 181-303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotation

Keywords - Domaini

Paired boxUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00680000099553.
OrthoDBiEOG79KPH3.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2ALK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQYYFIKPKV KYTSFLTFAC ASWTISCSRA VEITKPQPGK LKRHFAFCTP
60 70 80 90 100
TFAPPHPASC AGTCAAKPGP DPTGGDKLFP VRRISPNRMK FTLGLGSRAW
110 120 130 140 150
RVSWERAAAA AAGPGAGGAL GSGSLRVSSR RGPRLARALP LCLSGGGGAR
160 170 180 190 200
ALPDCAGPSP RRSGARQLAG PRAMEQTYGE VNQLGGVFVN GRPLPNAIRL
210 220 230 240 250
RIVELAQLGI RPCDISRQLR VSHGCVSKIL ARYNETGSIL PGAIGGSKPR
260 270 280 290 300
VTTPNVVKHI RDYKQGDPGI FAWEIRDRLL ADGVCDKYNV PSVSSISRIL
310 320 330 340 350
RNKIGSLAQP GPYEASKQPP PQPALPYNHI YQYPYPSPVS PTGTKMGTHP
360 370 380
GVPGSAGHVS IPRSWPSAHS VSNILGIRTF MEQTG
Length:385
Mass (Da):41,104
Last modified:March 3, 2009 - v1
Checksum:i4F58B9F947EC05B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei385 – 3851Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805918 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000126068; ENSMUSP00000119667; ENSMUSG00000037034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805918 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA2ALK0.
SMRiA2ALK0. Positions 181-303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105594.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000126068; ENSMUSP00000119667; ENSMUSG00000037034.

Organism-specific databases

MGIiMGI:97485. Pax1.

Phylogenomic databases

GeneTreeiENSGT00680000099553.
OrthoDBiEOG79KPH3.

Miscellaneous databases

NextBioi35543625.
SOURCEiSearch...

Gene expression databases

BgeeiA2ALK0.
ExpressionAtlasiA2ALK0. baseline and differential.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2ALK0_MOUSE
AccessioniPrimary (citable) accession number: A2ALK0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 24, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.