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A2ALK0

- A2ALK0_MOUSE

UniProt

A2ALK0 - A2ALK0_MOUSE

Protein
Submitted name:

Paired box protein Pax-1

Gene

Pax1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: MGI

    GO - Biological processi

    1. bone morphogenesis Source: MGI
    2. CD4-positive, alpha-beta T cell differentiation Source: MGI
    3. CD8-positive, alpha-beta T cell differentiation Source: MGI
    4. cell proliferation Source: MGI
    5. organ morphogenesis Source: MGI
    6. parathyroid gland development Source: MGI
    7. pattern specification process Source: MGI
    8. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    9. regulation of transcription, DNA-templated Source: MGI
    10. skeletal system development Source: MGI
    11. somitogenesis Source: MGI
    12. thymus development Source: MGI
    13. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental proteinUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Paired box protein Pax-1Imported
    Gene namesi
    Name:Pax1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:97485. Pax1.

    Subcellular locationi

    Nucleus UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell
    2. transcription factor complex Source: MGI

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliA2ALK0.
    SMRiA2ALK0. Positions 181-303.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 paired domain.UniRule annotation
    Contains paired domain.SAAS annotation

    Keywords - Domaini

    Paired boxUniRule annotationSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00680000099553.
    OMAiCASWTIS.
    OrthoDBiEOG79KPH3.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    InterProiIPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00292. PAX. 1 hit.
    [Graphical view]
    PRINTSiPR00027. PAIREDBOX.
    SMARTiSM00351. PAX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    A2ALK0-1 [UniParc]FASTAAdd to Basket

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    MQYYFIKPKV KYTSFLTFAC ASWTISCSRA VEITKPQPGK LKRHFAFCTP    50
    TFAPPHPASC AGTCAAKPGP DPTGGDKLFP VRRISPNRMK FTLGLGSRAW 100
    RVSWERAAAA AAGPGAGGAL GSGSLRVSSR RGPRLARALP LCLSGGGGAR 150
    ALPDCAGPSP RRSGARQLAG PRAMEQTYGE VNQLGGVFVN GRPLPNAIRL 200
    RIVELAQLGI RPCDISRQLR VSHGCVSKIL ARYNETGSIL PGAIGGSKPR 250
    VTTPNVVKHI RDYKQGDPGI FAWEIRDRLL ADGVCDKYNV PSVSSISRIL 300
    RNKIGSLAQP GPYEASKQPP PQPALPYNHI YQYPYPSPVS PTGTKMGTHP 350
    GVPGSAGHVS IPRSWPSAHS VSNILGIRTF MEQTG 385
    Length:385
    Mass (Da):41,104
    Last modified:March 3, 2009 - v1
    Checksum:i4F58B9F947EC05B3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei385 – 3851Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL805918 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000126068; ENSMUSP00000119667; ENSMUSG00000037034.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL805918 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali A2ALK0.
    SMRi A2ALK0. Positions 181-303.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000126068 ; ENSMUSP00000119667 ; ENSMUSG00000037034 .

    Organism-specific databases

    MGIi MGI:97485. Pax1.

    Phylogenomic databases

    GeneTreei ENSGT00680000099553.
    OMAi CASWTIS.
    OrthoDBi EOG79KPH3.

    Miscellaneous databases

    NextBioi 35543625.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    InterProi IPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00292. PAX. 1 hit.
    [Graphical view ]
    PRINTSi PR00027. PAIREDBOX.
    SMARTi SM00351. PAX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2ALK0_MOUSE
    AccessioniPrimary (citable) accession number: A2ALK0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3