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A2ALK0

- A2ALK0_MOUSE

UniProt

A2ALK0 - A2ALK0_MOUSE

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Protein
Submitted name:

Paired box protein Pax-1

Gene

Pax1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. bone morphogenesis Source: MGI
  2. CD4-positive, alpha-beta T cell differentiation Source: MGI
  3. CD8-positive, alpha-beta T cell differentiation Source: MGI
  4. cell proliferation Source: MGI
  5. organ morphogenesis Source: MGI
  6. parathyroid gland development Source: MGI
  7. pattern specification process Source: MGI
  8. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  9. regulation of transcription, DNA-templated Source: MGI
  10. skeletal system development Source: MGI
  11. somitogenesis Source: MGI
  12. thymus development Source: MGI
  13. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-1Imported
Gene namesi
Name:Pax1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:97485. Pax1.

Subcellular locationi

Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiA2ALK0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA2ALK0.
SMRiA2ALK0. Positions 181-303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotation

Keywords - Domaini

Paired boxUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00680000099553.
OMAiCASWTIS.
OrthoDBiEOG79KPH3.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2ALK0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQYYFIKPKV KYTSFLTFAC ASWTISCSRA VEITKPQPGK LKRHFAFCTP
60 70 80 90 100
TFAPPHPASC AGTCAAKPGP DPTGGDKLFP VRRISPNRMK FTLGLGSRAW
110 120 130 140 150
RVSWERAAAA AAGPGAGGAL GSGSLRVSSR RGPRLARALP LCLSGGGGAR
160 170 180 190 200
ALPDCAGPSP RRSGARQLAG PRAMEQTYGE VNQLGGVFVN GRPLPNAIRL
210 220 230 240 250
RIVELAQLGI RPCDISRQLR VSHGCVSKIL ARYNETGSIL PGAIGGSKPR
260 270 280 290 300
VTTPNVVKHI RDYKQGDPGI FAWEIRDRLL ADGVCDKYNV PSVSSISRIL
310 320 330 340 350
RNKIGSLAQP GPYEASKQPP PQPALPYNHI YQYPYPSPVS PTGTKMGTHP
360 370 380
GVPGSAGHVS IPRSWPSAHS VSNILGIRTF MEQTG
Length:385
Mass (Da):41,104
Last modified:March 3, 2009 - v1
Checksum:i4F58B9F947EC05B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei385 – 3851Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805918 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000126068; ENSMUSP00000119667; ENSMUSG00000037034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805918 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A2ALK0.
SMRi A2ALK0. Positions 181-303.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000126068 ; ENSMUSP00000119667 ; ENSMUSG00000037034 .

Organism-specific databases

MGIi MGI:97485. Pax1.

Phylogenomic databases

GeneTreei ENSGT00680000099553.
OMAi CASWTIS.
OrthoDBi EOG79KPH3.

Miscellaneous databases

NextBioi 35543625.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi A2ALK0. baseline and differential.

Family and domain databases

Gene3Di 1.10.10.10. 2 hits.
InterProi IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00292. PAX. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2ALK0_MOUSE
AccessioniPrimary (citable) accession number: A2ALK0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3