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A2ALK0

- A2ALK0_MOUSE

UniProt

A2ALK0 - A2ALK0_MOUSE

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Protein
Submitted name: Paired box protein Pax-1
Gene
Pax1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. CD4-positive, alpha-beta T cell differentiation Source: MGI
  2. CD8-positive, alpha-beta T cell differentiation Source: MGI
  3. bone morphogenesis Source: MGI
  4. cell proliferation Source: MGI
  5. organ morphogenesis Source: MGI
  6. parathyroid gland development Source: MGI
  7. pattern specification process Source: MGI
  8. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  9. regulation of transcription, DNA-templated Source: MGI
  10. skeletal system development Source: MGI
  11. somitogenesis Source: MGI
  12. thymus development Source: MGI
  13. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotations

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-1Imported
Gene namesi
Name:Pax1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:97485. Pax1.

Subcellular locationi

Nucleus By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliA2ALK0.
SMRiA2ALK0. Positions 181-303.

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotations

Keywords - Domaini

Paired boxUniRule annotationSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00680000099553.
OMAiCASWTIS.
OrthoDBiEOG79KPH3.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2ALK0-1 [UniParc]FASTAAdd to Basket

« Hide

MQYYFIKPKV KYTSFLTFAC ASWTISCSRA VEITKPQPGK LKRHFAFCTP    50
TFAPPHPASC AGTCAAKPGP DPTGGDKLFP VRRISPNRMK FTLGLGSRAW 100
RVSWERAAAA AAGPGAGGAL GSGSLRVSSR RGPRLARALP LCLSGGGGAR 150
ALPDCAGPSP RRSGARQLAG PRAMEQTYGE VNQLGGVFVN GRPLPNAIRL 200
RIVELAQLGI RPCDISRQLR VSHGCVSKIL ARYNETGSIL PGAIGGSKPR 250
VTTPNVVKHI RDYKQGDPGI FAWEIRDRLL ADGVCDKYNV PSVSSISRIL 300
RNKIGSLAQP GPYEASKQPP PQPALPYNHI YQYPYPSPVS PTGTKMGTHP 350
GVPGSAGHVS IPRSWPSAHS VSNILGIRTF MEQTG 385
Length:385
Mass (Da):41,104
Last modified:March 3, 2009 - v1
Checksum:i4F58B9F947EC05B3
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei385 – 3851Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL805918 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000126068; ENSMUSP00000119667; ENSMUSG00000037034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL805918 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A2ALK0.
SMRi A2ALK0. Positions 181-303.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000126068 ; ENSMUSP00000119667 ; ENSMUSG00000037034 .

Organism-specific databases

MGIi MGI:97485. Pax1.

Phylogenomic databases

GeneTreei ENSGT00680000099553.
OMAi CASWTIS.
OrthoDBi EOG79KPH3.

Miscellaneous databases

NextBioi 35543625.
SOURCEi Search...

Family and domain databases

Gene3Di 1.10.10.10. 2 hits.
InterProi IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00292. PAX. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2ALK0_MOUSE
AccessioniPrimary (citable) accession number: A2ALK0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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