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Protein

MAP7 domain-containing protein 1

Gene

Map7d1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
MAP7 domain-containing protein 1
Gene namesi
Name:Map7d1
Synonyms:Kiaa1187, Mtap7d1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2384297. Map7d1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003068081 – 846MAP7 domain-containing protein 1Add BLAST846

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei49PhosphothreonineBy similarity1
Modified residuei53PhosphothreonineCombined sources1
Modified residuei95PhosphoserineBy similarity1
Modified residuei99PhosphothreonineBy similarity1
Modified residuei115PhosphoserineBy similarity1
Modified residuei118PhosphoserineBy similarity1
Modified residuei120PhosphothreonineBy similarity1
Modified residuei125PhosphoserineBy similarity1
Modified residuei127PhosphoserineBy similarity1
Modified residuei256PhosphoserineBy similarity1
Modified residuei275PhosphoserineBy similarity1
Modified residuei315PhosphoserineCombined sources1
Modified residuei368PhosphoserineBy similarity1
Modified residuei401PhosphoserineBy similarity1
Modified residuei444PhosphoserineBy similarity1
Modified residuei448PhosphoserineBy similarity1
Modified residuei454PhosphoserineBy similarity1
Modified residuei460PhosphoserineBy similarity1
Modified residuei479PhosphoserineCombined sources1
Modified residuei496PhosphoserineCombined sources1
Modified residuei544PhosphoserineCombined sources1
Modified residuei548PhosphoserineCombined sources1
Modified residuei552PhosphoserineCombined sources1
Modified residuei554PhosphothreonineCombined sources1
Modified residuei818PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiA2AJI0.
MaxQBiA2AJI0.
PaxDbiA2AJI0.
PeptideAtlasiA2AJI0.
PRIDEiA2AJI0.

PTM databases

iPTMnetiA2AJI0.
PhosphoSitePlusiA2AJI0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028849.
ExpressionAtlasiA2AJI0. baseline and differential.
GenevisibleiA2AJI0. MM.

Interactioni

Protein-protein interaction databases

BioGridi232845. 2 interactors.
IntActiA2AJI0. 2 interactors.
MINTiMINT-4116390.
STRINGi10090.ENSMUSP00000054338.

Structurei

3D structure databases

ProteinModelPortaliA2AJI0.
SMRiA2AJI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili130 – 224Sequence analysisAdd BLAST95
Coiled coili414 – 443Sequence analysisAdd BLAST30
Coiled coili599 – 740Sequence analysisAdd BLAST142

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi5 – 129Pro-richAdd BLAST125
Compositional biasi467 – 595Pro-richAdd BLAST129

Sequence similaritiesi

Belongs to the MAP7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IH56. Eukaryota.
ENOG410XTH2. LUCA.
GeneTreeiENSGT00660000095160.
HOGENOMiHOG000231569.
HOVERGENiHBG071099.
InParanoidiA2AJI0.
KOiK16806.
OMAiAPQEPQW.
OrthoDBiEOG091G07NV.
PhylomeDBiA2AJI0.
TreeFamiTF332273.

Family and domain databases

InterProiIPR008604. MAP7_fam.
[Graphical view]
PANTHERiPTHR15073. PTHR15073. 2 hits.
PfamiPF05672. MAP7. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A2AJI0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MESGPRVEPG PGAPAAVLAR IPQEPRPSPE GDPSPPPPPT PMSALVPDTP
60 70 80 90 100
PDTPPALKTA TNPKQLPLEP GNPTGQISPQ PAPPQEECPS SEAKSRGPTP
110 120 130 140 150
TATGPREAKP SRRSSQPSPT TVPASDSPPA KQDVKKAGER HKLAKERREE
160 170 180 190 200
RAKYLAAKKA VWLEKEEKAK ALREKQLQER RRRLEEQRLK AEQRRAALEE
210 220 230 240 250
RQRQKLEKNK ERYEAAIQRS VKKTWAEIRQ QRWSWAGALH HSSPGRKTSG
260 270 280 290 300
SRCSVSAVNL PKHVDSIINK RLSKSSATLW NSPSRNRSLQ LSAWESSIVD
310 320 330 340 350
RLMTPTLSFL ARSRSAVTLP RNGRDQGRGS GPGRRPTRAR AGASLAPGPH
360 370 380 390 400
PDRTHPSAAV PVCPRSASAS PLTPCSAPRS AHRCTPSGER PERRKPGAGG
410 420 430 440 450
SPALARRRLE ATPVQKKEKK DKERENEKEK SALARERNLK KRQSLPASIR
460 470 480 490 500
PRLSTGSELS PKSKARPSSP STTWHRPASP CPSPGPGHAL PPKPPSPRGT
510 520 530 540 550
TASPKGRVRR KEEAKESPSP SGPEDKNHRK SRAAEEKEPA APASPAPSPV
560 570 580 590 600
PSPTPAQPQK EQSSTQIPAE TAVPAVPAAP TAPPTAAPSV TPSKPMAGTT
610 620 630 640 650
DREEATRLLA EKRRQAREQR EREEQERKLQ AERDKRMREE QLAREAEARA
660 670 680 690 700
EREAEARRRE EQEAREKAQA EQEEQERLQK QKEEAEARSR EEAERQRQER
710 720 730 740 750
EKHFQKEEQE RQERRKRLEE IMKRTRKSEA AETKKQDAKE TAANNSGPDP
760 770 780 790 800
VKAVETRPSG LQKDSMQKEE LAPQEPQWSL PSKEMPGSLV NGLQPLPAHQ
810 820 830 840
ENGFSPKGTA GDKSLGRTAE GLLPFAEAEA FLKKAVVQPP QVTEVL
Length:846
Mass (Da):93,276
Last modified:February 20, 2007 - v1
Checksum:i3B4EEDAFEAC93C56
GO
Isoform 2 (identifier: A2AJI0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     249-285: Missing.

Note: No experimental confirmation available.
Show »
Length:809
Mass (Da):89,310
Checksum:i955156C88A06DEE8
GO

Sequence cautioni

The sequence AAH16081 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH19977 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC65744 differs from that shown. The sequence differs from that shown because it is derived from pre-RNA.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123 – 125PAS → SAY in AAH23677 (PubMed:15489334).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_028489249 – 285Missing in isoform 2. 1 PublicationAdd BLAST37

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732624 Genomic DNA. Translation: CAM13850.1.
BC016081 mRNA. Translation: AAH16081.1. Different initiation.
BC019977 mRNA. Translation: AAH19977.1. Different initiation.
BC023677 mRNA. Translation: AAH23677.1.
AK122462 Transcribed RNA. Translation: BAC65744.3. Sequence problems.
CCDSiCCDS18646.1. [A2AJI0-1]
RefSeqiNP_659190.3. NM_144941.3. [A2AJI0-1]
XP_006503175.1. XM_006503112.3. [A2AJI0-2]
UniGeneiMm.266716.

Genome annotation databases

EnsembliENSMUST00000061143; ENSMUSP00000054338; ENSMUSG00000028849. [A2AJI0-1]
GeneIDi245877.
KEGGimmu:245877.
UCSCiuc008usy.1. mouse. [A2AJI0-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732624 Genomic DNA. Translation: CAM13850.1.
BC016081 mRNA. Translation: AAH16081.1. Different initiation.
BC019977 mRNA. Translation: AAH19977.1. Different initiation.
BC023677 mRNA. Translation: AAH23677.1.
AK122462 Transcribed RNA. Translation: BAC65744.3. Sequence problems.
CCDSiCCDS18646.1. [A2AJI0-1]
RefSeqiNP_659190.3. NM_144941.3. [A2AJI0-1]
XP_006503175.1. XM_006503112.3. [A2AJI0-2]
UniGeneiMm.266716.

3D structure databases

ProteinModelPortaliA2AJI0.
SMRiA2AJI0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi232845. 2 interactors.
IntActiA2AJI0. 2 interactors.
MINTiMINT-4116390.
STRINGi10090.ENSMUSP00000054338.

PTM databases

iPTMnetiA2AJI0.
PhosphoSitePlusiA2AJI0.

Proteomic databases

EPDiA2AJI0.
MaxQBiA2AJI0.
PaxDbiA2AJI0.
PeptideAtlasiA2AJI0.
PRIDEiA2AJI0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000061143; ENSMUSP00000054338; ENSMUSG00000028849. [A2AJI0-1]
GeneIDi245877.
KEGGimmu:245877.
UCSCiuc008usy.1. mouse. [A2AJI0-1]

Organism-specific databases

CTDi55700.
MGIiMGI:2384297. Map7d1.
RougeiSearch...

Phylogenomic databases

eggNOGiENOG410IH56. Eukaryota.
ENOG410XTH2. LUCA.
GeneTreeiENSGT00660000095160.
HOGENOMiHOG000231569.
HOVERGENiHBG071099.
InParanoidiA2AJI0.
KOiK16806.
OMAiAPQEPQW.
OrthoDBiEOG091G07NV.
PhylomeDBiA2AJI0.
TreeFamiTF332273.

Miscellaneous databases

PROiA2AJI0.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028849.
ExpressionAtlasiA2AJI0. baseline and differential.
GenevisibleiA2AJI0. MM.

Family and domain databases

InterProiIPR008604. MAP7_fam.
[Graphical view]
PANTHERiPTHR15073. PTHR15073. 2 hits.
PfamiPF05672. MAP7. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMA7D1_MOUSE
AccessioniPrimary (citable) accession number: A2AJI0
Secondary accession number(s): Q80TI3
, Q8CIL3, Q8VCG2, Q91YQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: February 20, 2007
Last modified: November 30, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.