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Protein

MAP7 domain-containing protein 1

Gene

Map7d1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
MAP7 domain-containing protein 1
Gene namesi
Name:Map7d1
Synonyms:Kiaa1187, Mtap7d1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2384297 Map7d1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003068081 – 846MAP7 domain-containing protein 1Add BLAST846

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei49PhosphothreonineBy similarity1
Modified residuei53PhosphothreonineCombined sources1
Modified residuei95PhosphoserineBy similarity1
Modified residuei99PhosphothreonineBy similarity1
Modified residuei115PhosphoserineBy similarity1
Modified residuei118PhosphoserineBy similarity1
Modified residuei120PhosphothreonineBy similarity1
Modified residuei125PhosphoserineBy similarity1
Modified residuei127PhosphoserineBy similarity1
Modified residuei256PhosphoserineBy similarity1
Modified residuei275PhosphoserineBy similarity1
Modified residuei315PhosphoserineCombined sources1
Modified residuei368PhosphoserineBy similarity1
Modified residuei401PhosphoserineBy similarity1
Modified residuei444PhosphoserineBy similarity1
Modified residuei448PhosphoserineBy similarity1
Modified residuei454PhosphoserineBy similarity1
Modified residuei460PhosphoserineBy similarity1
Cross-linki462Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei479PhosphoserineCombined sources1
Modified residuei496PhosphoserineCombined sources1
Modified residuei544PhosphoserineCombined sources1
Modified residuei548PhosphoserineCombined sources1
Modified residuei552PhosphoserineCombined sources1
Modified residuei554PhosphothreonineCombined sources1
Modified residuei818PhosphothreonineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiA2AJI0
MaxQBiA2AJI0
PaxDbiA2AJI0
PeptideAtlasiA2AJI0
PRIDEiA2AJI0

PTM databases

iPTMnetiA2AJI0
PhosphoSitePlusiA2AJI0

Expressioni

Gene expression databases

BgeeiENSMUSG00000028849
ExpressionAtlasiA2AJI0 baseline and differential
GenevisibleiA2AJI0 MM

Interactioni

Protein-protein interaction databases

BioGridi232845, 4 interactors
IntActiA2AJI0, 3 interactors
MINTiA2AJI0
STRINGi10090.ENSMUSP00000054338

Structurei

3D structure databases

ProteinModelPortaliA2AJI0
SMRiA2AJI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili130 – 224Sequence analysisAdd BLAST95
Coiled coili414 – 443Sequence analysisAdd BLAST30
Coiled coili599 – 740Sequence analysisAdd BLAST142

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi5 – 129Pro-richAdd BLAST125
Compositional biasi467 – 595Pro-richAdd BLAST129

Sequence similaritiesi

Belongs to the MAP7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IH56 Eukaryota
ENOG410XTH2 LUCA
GeneTreeiENSGT00660000095160
HOGENOMiHOG000231569
HOVERGENiHBG071099
InParanoidiA2AJI0
KOiK16806
OMAiGHTLPPK
OrthoDBiEOG091G07NV
PhylomeDBiA2AJI0
TreeFamiTF332273

Family and domain databases

InterProiView protein in InterPro
IPR008604 MAP7_fam
PANTHERiPTHR15073 PTHR15073, 1 hit
PfamiView protein in Pfam
PF05672 MAP7, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A2AJI0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MESGPRVEPG PGAPAAVLAR IPQEPRPSPE GDPSPPPPPT PMSALVPDTP
60 70 80 90 100
PDTPPALKTA TNPKQLPLEP GNPTGQISPQ PAPPQEECPS SEAKSRGPTP
110 120 130 140 150
TATGPREAKP SRRSSQPSPT TVPASDSPPA KQDVKKAGER HKLAKERREE
160 170 180 190 200
RAKYLAAKKA VWLEKEEKAK ALREKQLQER RRRLEEQRLK AEQRRAALEE
210 220 230 240 250
RQRQKLEKNK ERYEAAIQRS VKKTWAEIRQ QRWSWAGALH HSSPGRKTSG
260 270 280 290 300
SRCSVSAVNL PKHVDSIINK RLSKSSATLW NSPSRNRSLQ LSAWESSIVD
310 320 330 340 350
RLMTPTLSFL ARSRSAVTLP RNGRDQGRGS GPGRRPTRAR AGASLAPGPH
360 370 380 390 400
PDRTHPSAAV PVCPRSASAS PLTPCSAPRS AHRCTPSGER PERRKPGAGG
410 420 430 440 450
SPALARRRLE ATPVQKKEKK DKERENEKEK SALARERNLK KRQSLPASIR
460 470 480 490 500
PRLSTGSELS PKSKARPSSP STTWHRPASP CPSPGPGHAL PPKPPSPRGT
510 520 530 540 550
TASPKGRVRR KEEAKESPSP SGPEDKNHRK SRAAEEKEPA APASPAPSPV
560 570 580 590 600
PSPTPAQPQK EQSSTQIPAE TAVPAVPAAP TAPPTAAPSV TPSKPMAGTT
610 620 630 640 650
DREEATRLLA EKRRQAREQR EREEQERKLQ AERDKRMREE QLAREAEARA
660 670 680 690 700
EREAEARRRE EQEAREKAQA EQEEQERLQK QKEEAEARSR EEAERQRQER
710 720 730 740 750
EKHFQKEEQE RQERRKRLEE IMKRTRKSEA AETKKQDAKE TAANNSGPDP
760 770 780 790 800
VKAVETRPSG LQKDSMQKEE LAPQEPQWSL PSKEMPGSLV NGLQPLPAHQ
810 820 830 840
ENGFSPKGTA GDKSLGRTAE GLLPFAEAEA FLKKAVVQPP QVTEVL
Length:846
Mass (Da):93,276
Last modified:February 20, 2007 - v1
Checksum:i3B4EEDAFEAC93C56
GO
Isoform 2 (identifier: A2AJI0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     249-285: Missing.

Note: No experimental confirmation available.
Show »
Length:809
Mass (Da):89,310
Checksum:i955156C88A06DEE8
GO

Sequence cautioni

The sequence AAH16081 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH19977 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC65744 differs from that shown. The sequence differs from that shown because it is derived from pre-RNA.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123 – 125PAS → SAY in AAH23677 (PubMed:15489334).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_028489249 – 285Missing in isoform 2. 1 PublicationAdd BLAST37

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732624 Genomic DNA Translation: CAM13850.1
BC016081 mRNA Translation: AAH16081.1 Different initiation.
BC019977 mRNA Translation: AAH19977.1 Different initiation.
BC023677 mRNA Translation: AAH23677.1
AK122462 Transcribed RNA Translation: BAC65744.3 Sequence problems.
CCDSiCCDS18646.1 [A2AJI0-1]
RefSeqiNP_659190.3, NM_144941.3 [A2AJI0-1]
XP_006503175.1, XM_006503112.3 [A2AJI0-2]
UniGeneiMm.266716

Genome annotation databases

EnsembliENSMUST00000061143; ENSMUSP00000054338; ENSMUSG00000028849 [A2AJI0-1]
GeneIDi245877
KEGGimmu:245877
UCSCiuc008usy.1 mouse [A2AJI0-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiMA7D1_MOUSE
AccessioniPrimary (citable) accession number: A2AJI0
Secondary accession number(s): Q80TI3
, Q8CIL3, Q8VCG2, Q91YQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: February 20, 2007
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health