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Protein

Transmembrane protein 141

Gene

Tmem141

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 141
Gene namesi
Name:Tmem141
Synonyms:D2Ertd217e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1098773 Tmem141

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 52HelicalSequence analysisAdd BLAST23
Transmembranei59 – 78HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002937091 – 108Transmembrane protein 141Add BLAST108

Proteomic databases

MaxQBiA2AJB2
PaxDbiA2AJB2
PeptideAtlasiA2AJB2
PRIDEiA2AJB2

PTM databases

iPTMnetiA2AJB2

Expressioni

Gene expression databases

BgeeiENSMUSG00000026939
CleanExiMM_TMEM141
ExpressionAtlasiA2AJB2 baseline and differential
GenevisibleiA2AJB2 MM

Structurei

3D structure databases

ProteinModelPortaliA2AJB2
SMRiA2AJB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM141 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0CX Eukaryota
ENOG4111TIE LUCA
GeneTreeiENSGT00390000001064
HOVERGENiHBG067289
InParanoidiA2AJB2
OMAiCQSHAFM
OrthoDBiEOG091G0X78
PhylomeDBiA2AJB2
TreeFamiTF330755

Family and domain databases

Gene3Di1.10.3350.20, 1 hit
InterProiView protein in InterPro
IPR026788 Tmem141
IPR038259 Tmem141_sf
PfamiView protein in Pfam
PF15110 TMEM141, 1 hit

Sequencei

Sequence statusi: Complete.

A2AJB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNLGLSRVD DAVAARHPGL EEFAACQSHA FMKGVFTFVT GTGATFGLLM
60 70 80 90 100
FIKRKFPYPV QWSFLVSAIA GSVASYRVTS MECQKCSNLW LFLETGQLPK

DISTDPHD
Length:108
Mass (Da):11,893
Last modified:February 20, 2007 - v1
Checksum:i383B16E3DC1E7485
GO

Sequence cautioni

The sequence AK004380 differs from that shown. Reason: Frameshift at position 18.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004380 mRNA No translation available.
AL732590 Genomic DNA No translation available.
CCDSiCCDS50534.1
RefSeqiNP_001035219.2, NM_001040130.3
UniGeneiMm.271147

Genome annotation databases

EnsembliENSMUST00000142087; ENSMUSP00000121862; ENSMUSG00000026939
GeneIDi51875
KEGGimmu:51875
UCSCiuc008isx.2 mouse

Similar proteinsi

Entry informationi

Entry nameiTM141_MOUSE
AccessioniPrimary (citable) accession number: A2AJB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: February 20, 2007
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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