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Protein

Transmembrane protein 141

Gene

Tmem141

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 141
Gene namesi
Name:Tmem141
Synonyms:D2Ertd217e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1098773. Tmem141.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 52HelicalSequence analysisAdd BLAST23
Transmembranei59 – 78HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002937091 – 108Transmembrane protein 141Add BLAST108

Proteomic databases

MaxQBiA2AJB2.
PaxDbiA2AJB2.
PeptideAtlasiA2AJB2.
PRIDEiA2AJB2.

PTM databases

iPTMnetiA2AJB2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000026939.
CleanExiMM_TMEM141.
ExpressionAtlasiA2AJB2. baseline and differential.
GenevisibleiA2AJB2. MM.

Structurei

3D structure databases

ProteinModelPortaliA2AJB2.
SMRiA2AJB2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM141 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0CX. Eukaryota.
ENOG4111TIE. LUCA.
GeneTreeiENSGT00390000001064.
HOVERGENiHBG067289.
InParanoidiA2AJB2.
OMAiCQSHAFM.
OrthoDBiEOG091G0X78.
PhylomeDBiA2AJB2.
TreeFamiTF330755.

Family and domain databases

InterProiView protein in InterPro
IPR026788. Tmem141.
PfamiView protein in Pfam
PF15110. TMEM141. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AJB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNLGLSRVD DAVAARHPGL EEFAACQSHA FMKGVFTFVT GTGATFGLLM
60 70 80 90 100
FIKRKFPYPV QWSFLVSAIA GSVASYRVTS MECQKCSNLW LFLETGQLPK

DISTDPHD
Length:108
Mass (Da):11,893
Last modified:February 20, 2007 - v1
Checksum:i383B16E3DC1E7485
GO

Sequence cautioni

The sequence AK004380 differs from that shown. Reason: Frameshift at position 18.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004380 mRNA. No translation available.
AL732590 Genomic DNA. Translation: CAM25175.1.
CCDSiCCDS50534.1.
RefSeqiNP_001035219.2. NM_001040130.3.
UniGeneiMm.271147.

Genome annotation databases

EnsembliENSMUST00000142087; ENSMUSP00000121862; ENSMUSG00000026939.
GeneIDi51875.
KEGGimmu:51875.
UCSCiuc008isx.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiTM141_MOUSE
AccessioniPrimary (citable) accession number: A2AJB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: February 20, 2007
Last modified: October 25, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families