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A2AJ26 (A2AJ26_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

ATP-binding cassette, sub-family A (ABC1), member 2 EMBL EDL08245.1
Gene names
Name:Abca2 EMBL EDL08245.1 Ensembl ENSMUSP00000099983 MGI 99606
ORF Names:mCG_18727 EMBL EDL08245.1
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000099983
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length2433 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. RuleBase RU000684

Sequences

Sequence LengthMass (Da)Tools
A2AJ26 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: D5E92BDFA06C0AF6

FASTA2,433270,525
        10         20         30         40         50         60 
MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP 

        70         80         90        100        110        120 
LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLH RVVEEGNLFD PVRPSLGSEL 

       130        140        150        160        170        180 
EALRQRLEAL SSGPGTWESH SARPAVSSFS LDSVARDQRE LWRFLMQNLS LPNSTAQALL 

       190        200        210        220        230        240 
AARVDPSEVY RLLFGPLPDL DGKLGFLRKQ EPWSRLGSNP LLQMEELLLA PALLEQLTCA 

       250        260        270        280        290        300 
PGSGELGRIL TMPEGHQVDL QGYRDAVCSG QATARAQRFS DLAAELRNQL DTAKIAQQLG 

       310        320        330        340        350        360 
FDVPNGSDPQ PQAPSPQSLP ALLGDLLDAQ KLLQDVDVLS ALALLLPQGA CAGQASAPQA 

       370        380        390        400        410        420 
SSLNGLANST GIGANSGSNT TVEEGTQSPV SPASPDTLQG QCSAFVQLWA GLQPILCGNN 

       430        440        450        460        470        480 
RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPVGSEADR VILKANETFA 

       490        500        510        520        530        540 
FVGNVTHYAQ VWLNISTEIR SFLEQGRLQQ HLQWLQQYVA DLQLHPEAMN LSLEELPPAL 

       550        560        570        580        590        600 
RQDFSLPNGT ALLQQLDTID NAACGWIQFM SKVSVDIFKG FPDEESIVNY TLNQAYQDNV 

       610        620        630        640        650        660 
TVFASVIFQT RKDGSLPPHV HYKIRQNSSF TEKTNEIRRA YWRPGPNTGG RFYFLYGFVW 

       670        680        690        700        710        720 
IQDMMERAII NTFVGHDVVE PGNYVQMFPY PCYTRDDFLF VIEHMMPLCM VISWVYSVAM 

       730        740        750        760        770        780 
TIQHIVAEKE HRLKEVMKTM GLNNAVHWVA WFITGFVQLS ISVTALTAIL KYGQVLMHSH 

       790        800        810        820        830        840 
VLIIWLFLAV YAVATIMFCF LVSVLYSKAK LASACGGIIY FLSYVPYMYV AIREEVAHDK 

       850        860        870        880        890        900 
ITAFEKCIAS LMSTTAFGLG SKYFALYEVA GVGIQWHTFS QSPVEGDDFN LLLAVTMLMV 

       910        920        930        940        950        960 
DTVVYGVLTW YIEAVHPGMY GLPRPWYFPL QKSYWLGSGR TEAWEWSWPW AHTPRLSVME 

       970        980        990       1000       1010       1020 
EDQACAMESR HFEETRGMEE EPTHLPLVVC VDKLTKVYKN DKKMALNKLS LNLYENQVVS 

      1030       1040       1050       1060       1070       1080 
FLGHNGAGKT TTMSILTGLF PPTSGSATIY GHDIRTEMDE IRKNLGMCPQ HNVLFDRLTV 

      1090       1100       1110       1120       1130       1140 
EEHLWFYSRL KSMAQEEIRK ETDKMIEDLE LSNKRHSLVQ TLSGGMKRKL SVAIAFVGGS 

      1150       1160       1170       1180       1190       1200 
RAIILDEPTA GVDPYARRAI WDLILKYKPG RTILLSTHHM DEADLLGDRI AIISHGKLKC 

      1210       1220       1230       1240       1250       1260 
CGSPLFLKGA YGDGYRLTLV KQPAEPGTSQ EPGLASSPSG CPRLSSCSEP QVSQFIRKHV 

      1270       1280       1290       1300       1310       1320 
ASSLLVSDTS TELSYILPSE AVKKGAFERL FQQLEHSLDA LHLSSFGLMD TTLEEVFLKV 

      1330       1340       1350       1360       1370       1380 
SEEDQSLENS EADVKESRKD VLPGAEGLTA VGGQAGNLAR CSELAQSQAS LQSASSVGSA 

      1390       1400       1410       1420       1430       1440 
RGEEGTGYSD GYGDYRPLFD NLQDPDNVSL QEAEMEALAQ VGQGSRKLEG WWLKMRQFHG 

      1450       1460       1470       1480       1490       1500 
LLVKRFHCAR RNSKALCSQI LLPAFFVCVA MTVALSVPEI GDLPPLVLSP SQYHNYTQPR 

      1510       1520       1530       1540       1550       1560 
GNFIPYANEE RQEYRLRLSP DASPQQLVST FRLPSGVGAT CVLKSPANGS LGPMLNLSSG 

      1570       1580       1590       1600       1610       1620 
ESRLLAARFF DSMCLESFTQ GLPLSNFVPP PPSPAPSDSP VSPDEDSLQA WNMSLPPTAG 

      1630       1640       1650       1660       1670       1680 
PETWTSAPSL PRLVHEPVRC TCSAQGTGFS CPSSVGGHPP QMRVVTGDIL TDITGHNVSE 

      1690       1700       1710       1720       1730       1740 
YLLFTSDRFR LHRYGAITFG NVQKSIPASF GARVPPMVRK IAVRRVAQVL YNNKGYHSMP 

      1750       1760       1770       1780       1790       1800 
TYLNSLNNAI LRANLPKSKG NPAAYGITVT NHPMNKTSAS LSLDYLLQGT DVVIAIFIIV 

      1810       1820       1830       1840       1850       1860 
AMSFVPASFV VFLVAEKSTK AKHLQFVSGC NPVIYWLANY VWDMLNYLVP ATCCVIILFV 

      1870       1880       1890       1900       1910       1920 
FDLPAYTSPT NFPAVLSLFL LYGWSITPIM YPASFWFEVP SSAYVFLIVI NLFIGITATV 

      1930       1940       1950       1960       1970       1980 
ATFLLQLFEH DKDLKVVNSY LKSCFLIFPN YNLGHGLMEM AYNEYINEYY AKIGQFDKMK 

      1990       2000       2010       2020       2030       2040 
SPFEWDIVTR GLVAMTVEGF VGFFLTIMCQ YNFLRQPQRL PVSTKPVEDD VDVASERQRV 

      2050       2060       2070       2080       2090       2100 
LRGDADNDMV KIENLTKVYK SRKIGRILAV DRLCLGVRPG ECFGLLGVNG AGKTSTFKML 

      2110       2120       2130       2140       2150       2160 
TGDESTTGGE AFVNGHSVLK DLLQVQQSLG YCPQFDALFD ELTAREHLQL YTRLRGIPWK 

      2170       2180       2190       2200       2210       2220 
DEAQVVKWAL EKLELTKYAD KPAGTYSGGN KRKLSTAIAL IGYPAFIFLD EPTTGMDPKA 

      2230       2240       2250       2260       2270       2280 
RRFLWNLILD LIKTGRSVVL TSHSMEECEA LCTRLAIMVN GRLRCLGSIQ HLKNRFGDGY 

      2290       2300       2310       2320       2330       2340 
MITVRTKSSQ NVKDVVRFFN RNFPEAMLKE RHHTKVQYQL KSEHISLAQV FSKMEQVVGV 

      2350       2360       2370       2380       2390       2400 
LGIEDYSVSQ TTLDNVFVNF AKKQSDNVEQ QEAEPSSLPS PLGLLSLLRP RPAPTELRAL 

      2410       2420       2430 
VADEPEDLDT EDEGLISFEE ERAQLSFNTD TLC 

« Hide

References

« Hide 'large scale' references
[1]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL08245.1.
[2]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL08245.1.
[3]"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[4]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000099983.
[5]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000099983.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL732557 Genomic DNA. No translation available.
CH466542 Genomic DNA. Translation: EDL08245.1.
RefSeqNP_031405.2. NM_007379.2.
UniGeneMm.2210.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000102919; ENSMUSP00000099983; ENSMUSG00000026944.
GeneID11305.
KEGGmmu:11305.
UCSCuc008isc.1. mouse.

Organism-specific databases

CTD20.
MGIMGI:99606. Abca2.

Phylogenomic databases

GeneTreeENSGT00720000108414.
HOGENOMHOG000231547.
HOVERGENHBG050436.
InParanoidA2AJ26.
KOK05642.
OMAGYPAFIF.
OrthoDBEOG78D7J6.
TreeFamTF105191.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
InterProIPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR19229. PTHR19229. 1 hit.
PfamPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSABCA2. mouse.
NextBio278594.
SOURCESearch...

Entry information

Entry nameA2AJ26_MOUSE
AccessionPrimary (citable) accession number: A2AJ26
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)