Protein Grin3a - Mus musculus (Mouse)

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A2AIR5 (A2AIR5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 55. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Protein Grin3a Ensembl ENSMUSP00000091381

Gene names

Name:

Grin3a Ensembl ENSMUSP00000091381 MGI 1933206

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000091381

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1135 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000091381

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell junction Cell membrane SAAS SAAS019594 Membrane Postsynaptic cell membrane SAAS SAAS019594 Synapse
Domain	Transmembrane Transmembrane helix SAAS SAAS019594
Molecular function	Ion channel Ligand-gated ion channel SAAS SAAS019594 Receptor SAAS SAAS019594
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	dendrite development Inferred from mutant phenotype PubMed 9620802. Source: MGI prepulse inhibition Inferred from mutant phenotype PubMed 15866554. Source: MGI
Cellular_component	cell junction Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW neuronal cell body Inferred from direct assay PubMed 14507892. Source: MGI outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW postsynaptic membrane Inferred from direct assay PubMed 9620802. Source: MGI
Molecular_function	N-methyl-D-aspartate selective glutamate receptor activity Inferred from mutant phenotype PubMed 14507892. Source: MGI calcium channel activity Inferred from direct assay PubMed 9620802. Source: MGI extracellular-glutamate-gated ion channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A2AIR5 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 71DBEF3EDFFA2A7E
Show »

FASTA

1,135

127,542

        10         20         30         40         50         60 
MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV GAVHLQPWTT 

        70         80         90        100        110        120 
APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS ALHGRGPPGS RKLGEGAGTE 

       130        140        150        160        170        180 
TLWPRDALLF AVENLNRVEG LLPYNLSLEV VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF 

       190        200        210        220        230        240 
LQSVCHTVVV QGVSALLAFP QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL 

       250        260        270        280        290        300 
SLENSLSSDA DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN 

       310        320        330        340        350        360 
LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP DLHWVLGDSQ 

       370        380        390        400        410        420 
NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV ATATMIQPEL ALLPSTMNCM 

       430        440        450        460        470        480 
DVKTTNLTSG QYLSRFLANT TFRGLSGSIK VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR 

       490        500        510        520        530        540 
LGSWQGGRIV MDSGIWPEQA QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG 

       550        560        570        580        590        600 
QLCLDPMTND SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV 

       610        620        630        640        650        660 
GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS TSLGILVRTR 

       670        680        690        700        710        720 
DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP FGMTPKGRNR NKVFSFSSAL 

       730        740        750        760        770        780 
NVCYALLFGR TAAIKPPKCW TGRFLMNLWA IFCMFCLSTY TANLAAVMVG EKIYEELSGI 

       790        800        810        820        830        840 
HDPKLHHPSQ GFRFGTVRES SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD 

       850        860        870        880        890        900 
AFIMDKALLD YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM 

       910        920        930        940        950        960 
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI GEHIVYRLLL 

       970        980        990       1000       1010       1020 
PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV EKSRWRRWTC KTEGDSELSL 

      1030       1040       1050       1060       1070       1080 
FPRSNMGPQQ LMVWNTSNLS HDNQRKYIFN DEEGQNQLGT QTHQDIPLPP RRRELPASLT 

      1090       1100       1110       1120       1130 
TNGKADSLNV ARNSVMQELS ELEKQIQVIR QELQLAVSRK TELEEYQRTN RTCES

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000091381.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000091381.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL732521 Genomic DNA. No translation available. AL807392 Genomic DNA. No translation available.
IPI	IPI00112337.
RefSeq	NP_001263284.1. NM_001276355.1.
UniGene	Mm.440095.
3D structure databases
ProteinModelPortal	A2AIR5.
SMR	A2AIR5. Positions 143-497, 512-952.
ModBase	Search...
Proteomic databases
PRIDE	A2AIR5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000093859; ENSMUSP00000091381; ENSMUSG00000039579.
GeneID	242443.
Organism-specific databases
MGI	MGI:1933206. Grin3a.
Phylogenomic databases
GeneTree	ENSGT00700000104113.
HOGENOM	HOG000231528.
HOVERGEN	HBG052634.
InParanoid	A2AIR5.
OMA	QSQGEMM.
OrthoDB	EOG480HW2.
Gene expression databases
ArrayExpress	A2AIR5.
Family and domain databases
InterPro	IPR019594. Glu_rcpt_Glu/Gly-bd. IPR001320. Iontro_glu_rcpt. IPR001508. NMDA_rcpt. IPR001638. SBP_bac_3. [Graphical view]
Pfam	PF00060. Lig_chan. 1 hit. PF00497. SBP_bac_3. 1 hit. [Graphical view]
PRINTS	PR00177. NMDARECEPTOR.
SMART	SM00918. Lig_chan-Glu_bd. 1 hit. SM00079. PBPe. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChEMBL	CHEMBL2562.
NextBio	35543421.
SOURCE	Search...

Entry information

Entry name

A2AIR5_MOUSE

Accession

Primary (citable) accession number: A2AIR5

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information