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A2AIR5 (A2AIR5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1135 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000091381

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentCell junction
Cell membrane SAAS SAAS001508
Membrane
Postsynaptic cell membrane SAAS SAAS001508
Synapse
   DomainTransmembrane
Transmembrane helix SAAS SAAS001638
   Molecular functionIon channel
Ligand-gated ion channel SAAS SAAS001638
Receptor SAAS SAAS001638
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcalcium ion transmembrane transport

Inferred from direct assay PubMed 9620802. Source: GOC

calcium ion transport

Inferred from mutant phenotype PubMed 14507892. Source: MGI

dendrite development

Inferred from mutant phenotype PubMed 9620802. Source: MGI

ionotropic glutamate receptor signaling pathway

Inferred from mutant phenotype PubMed 14507892. Source: GOC

prepulse inhibition

Inferred from mutant phenotype PubMed 15866554. Source: MGI

   Cellular_componentcell junction

Inferred from electronic annotation. Source: UniProtKB-KW

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

neuronal cell body

Inferred from direct assay PubMed 14507892. Source: MGI

postsynaptic membrane

Inferred from direct assay PubMed 9620802. Source: MGI

   Molecular_functionN-methyl-D-aspartate selective glutamate receptor activity

Inferred from mutant phenotype PubMed 14507892. Source: MGI

calcium channel activity

Inferred from direct assay PubMed 9620802. Source: MGI

extracellular-glutamate-gated ion channel activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A2AIR5 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 71DBEF3EDFFA2A7E

FASTA1,135127,542
        10         20         30         40         50         60 
MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV GAVHLQPWTT 

        70         80         90        100        110        120 
APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS ALHGRGPPGS RKLGEGAGTE 

       130        140        150        160        170        180 
TLWPRDALLF AVENLNRVEG LLPYNLSLEV VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF 

       190        200        210        220        230        240 
LQSVCHTVVV QGVSALLAFP QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL 

       250        260        270        280        290        300 
SLENSLSSDA DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN 

       310        320        330        340        350        360 
LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP DLHWVLGDSQ 

       370        380        390        400        410        420 
NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV ATATMIQPEL ALLPSTMNCM 

       430        440        450        460        470        480 
DVKTTNLTSG QYLSRFLANT TFRGLSGSIK VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR 

       490        500        510        520        530        540 
LGSWQGGRIV MDSGIWPEQA QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG 

       550        560        570        580        590        600 
QLCLDPMTND SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV 

       610        620        630        640        650        660 
GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS TSLGILVRTR 

       670        680        690        700        710        720 
DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP FGMTPKGRNR NKVFSFSSAL 

       730        740        750        760        770        780 
NVCYALLFGR TAAIKPPKCW TGRFLMNLWA IFCMFCLSTY TANLAAVMVG EKIYEELSGI 

       790        800        810        820        830        840 
HDPKLHHPSQ GFRFGTVRES SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD 

       850        860        870        880        890        900 
AFIMDKALLD YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM 

       910        920        930        940        950        960 
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI GEHIVYRLLL 

       970        980        990       1000       1010       1020 
PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV EKSRWRRWTC KTEGDSELSL 

      1030       1040       1050       1060       1070       1080 
FPRSNMGPQQ LMVWNTSNLS HDNQRKYIFN DEEGQNQLGT QTHQDIPLPP RRRELPASLT 

      1090       1100       1110       1120       1130 
TNGKADSLNV ARNSVMQELS ELEKQIQVIR QELQLAVSRK TELEEYQRTN RTCES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqNP_001263284.1. NM_001276355.1.
UniGeneMm.440095.

3D structure databases

ProteinModelPortalA2AIR5.
SMRA2AIR5. Positions 512-662, 776-908.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA2AIR5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000093859; ENSMUSP00000091381; ENSMUSG00000039579.
GeneID242443.
KEGGmmu:242443.

Organism-specific databases

CTD116443.
MGIMGI:1933206. Grin3a.

Phylogenomic databases

GeneTreeENSGT00740000115410.
HOGENOMHOG000231528.
HOVERGENHBG052634.
InParanoidA2AIR5.
KOK05213.
OMAMNCMEVE.
OrthoDBEOG7QK0B4.
PhylomeDBA2AIR5.

Gene expression databases

ArrayExpressA2AIR5.

Family and domain databases

InterProIPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
IPR001638. SBP_bac_3.
[Graphical view]
PfamPF00060. Lig_chan. 1 hit.
PF00497. SBP_bac_3. 1 hit.
[Graphical view]
PRINTSPR00177. NMDARECEPTOR.
SMARTSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMSSF53822. SSF53822. 1 hit.
ProtoNetSearch...

Other

NextBio35543421.
PROA2AIR5.
SOURCESearch...

Entry information

Entry nameA2AIR5_MOUSE
AccessionPrimary (citable) accession number: A2AIR5
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)