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Protein
Submitted name:

Protein Grin3a

Gene

Grin3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium channel activity Source: MGI
  2. extracellular-glutamate-gated ion channel activity Source: GO_Central
  3. glycine binding Source: MGI
  4. identical protein binding Source: MGI
  5. neurotransmitter binding Source: Ensembl
  6. N-methyl-D-aspartate selective glutamate receptor activity Source: MGI

GO - Biological processi

  1. calcium ion transmembrane transport Source: GOC
  2. calcium ion transport Source: MGI
  3. dendrite development Source: MGI
  4. ion transmembrane transport Source: GOC
  5. prepulse inhibition Source: MGI
  6. response to ethanol Source: MGI
  7. rhythmic process Source: Ensembl
  8. synaptic transmission, glutamatergic Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Grin3aImported
Gene namesi
Name:Grin3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:1933206. Grin3a.

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. dendrite Source: GO_Central
  3. membrane Source: MGI
  4. neuronal cell body Source: MGI
  5. neuron projection Source: MGI
  6. N-methyl-D-aspartate selective glutamate receptor complex Source: MGI
  7. postsynaptic membrane Source: MGI
  8. synapse Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Proteomic databases

PRIDEiA2AIR5.

Expressioni

Gene expression databases

ExpressionAtlasiA2AIR5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA2AIR5.
SMRiA2AIR5. Positions 512-662, 776-908.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119186.
HOGENOMiHOG000231528.
HOVERGENiHBG052634.
InParanoidiA2AIR5.
KOiK05213.
OMAiTQFGVMP.
OrthoDBiEOG7QK0B4.
PhylomeDBiA2AIR5.

Family and domain databases

InterProiIPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AIR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV
60 70 80 90 100
GAVHLQPWTT APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS
110 120 130 140 150
ALHGRGPPGS RKLGEGAGTE TLWPRDALLF AVENLNRVEG LLPYNLSLEV
160 170 180 190 200
VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF LQSVCHTVVV QGVSALLAFP
210 220 230 240 250
QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL SLENSLSSDA
260 270 280 290 300
DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN
310 320 330 340 350
LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP
360 370 380 390 400
DLHWVLGDSQ NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV
410 420 430 440 450
ATATMIQPEL ALLPSTMNCM DVKTTNLTSG QYLSRFLANT TFRGLSGSIK
460 470 480 490 500
VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR LGSWQGGRIV MDSGIWPEQA
510 520 530 540 550
QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG QLCLDPMTND
560 570 580 590 600
SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV
610 620 630 640 650
GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS
660 670 680 690 700
TSLGILVRTR DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP
710 720 730 740 750
FGMTPKGRNR NKVFSFSSAL NVCYALLFGR TAAIKPPKCW TGRFLMNLWA
760 770 780 790 800
IFCMFCLSTY TANLAAVMVG EKIYEELSGI HDPKLHHPSQ GFRFGTVRES
810 820 830 840 850
SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD AFIMDKALLD
860 870 880 890 900
YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM
910 920 930 940 950
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI
960 970 980 990 1000
GEHIVYRLLL PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV
1010 1020 1030 1040 1050
EKSRWRRWTC KTEGDSELSL FPRSNMGPQQ LMVWNTSNLS HDNQRKYIFN
1060 1070 1080 1090 1100
DEEGQNQLGT QTHQDIPLPP RRRELPASLT TNGKADSLNV ARNSVMQELS
1110 1120 1130
ELEKQIQVIR QELQLAVSRK TELEEYQRTN RTCES
Length:1,135
Mass (Da):127,542
Last modified:February 20, 2007 - v1
Checksum:i71DBEF3EDFFA2A7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqiNP_001263284.1. NM_001276355.1.
UniGeneiMm.440095.

Genome annotation databases

EnsembliENSMUST00000093859; ENSMUSP00000091381; ENSMUSG00000039579.
GeneIDi242443.
KEGGimmu:242443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqiNP_001263284.1. NM_001276355.1.
UniGeneiMm.440095.

3D structure databases

ProteinModelPortaliA2AIR5.
SMRiA2AIR5. Positions 512-662, 776-908.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA2AIR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000093859; ENSMUSP00000091381; ENSMUSG00000039579.
GeneIDi242443.
KEGGimmu:242443.

Organism-specific databases

CTDi116443.
MGIiMGI:1933206. Grin3a.

Phylogenomic databases

GeneTreeiENSGT00760000119186.
HOGENOMiHOG000231528.
HOVERGENiHBG052634.
InParanoidiA2AIR5.
KOiK05213.
OMAiTQFGVMP.
OrthoDBiEOG7QK0B4.
PhylomeDBiA2AIR5.

Miscellaneous databases

ChiTaRSiGrin3a. mouse.
NextBioi35543421.
PROiA2AIR5.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiA2AIR5. baseline and differential.

Family and domain databases

InterProiIPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AIR5_MOUSE
AccessioniPrimary (citable) accession number: A2AIR5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: March 4, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.