Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein Grin3a

Gene

Grin3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • calcium channel activity Source: MGI
  • extracellular-glutamate-gated ion channel activity Source: GO_Central
  • glycine binding Source: MGI
  • identical protein binding Source: MGI
  • N-methyl-D-aspartate selective glutamate receptor activity Source: MGI

GO - Biological processi

  • calcium ion transmembrane transport Source: GOC
  • calcium ion transport Source: MGI
  • dendrite development Source: MGI
  • ionotropic glutamate receptor signaling pathway Source: GOC
  • ion transmembrane transport Source: GOC
  • prepulse inhibition Source: MGI
  • response to ethanol Source: MGI
  • synaptic transmission, glutamatergic Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Grin3aImported
Gene namesi
Name:Grin3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1933206. Grin3a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Proteomic databases

MaxQBiA2AIR4.
PaxDbiA2AIR4.
PRIDEiA2AIR4.

Expressioni

Gene expression databases

BgeeiA2AIR4.
ExpressionAtlasiA2AIR4. baseline and differential.
GenevisibleiA2AIR4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075970.

Structurei

3D structure databases

ProteinModelPortaliA2AIR4.
SMRiA2AIR4. Positions 143-941.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG320645.
GeneTreeiENSGT00760000119186.
HOGENOMiHOG000231528.
HOVERGENiHBG052634.
KOiK05213.
TreeFamiTF314731.

Family and domain databases

InterProiIPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AIR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV
60 70 80 90 100
GAVHLQPWTT APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS
110 120 130 140 150
ALHGRGPPGS RKLGEGAGTE TLWPRDALLF AVENLNRVEG LLPYNLSLEV
160 170 180 190 200
VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF LQSVCHTVVV QGVSALLAFP
210 220 230 240 250
QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL SLENSLSSDA
260 270 280 290 300
DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN
310 320 330 340 350
LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP
360 370 380 390 400
DLHWVLGDSQ NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV
410 420 430 440 450
ATATMIQPEL ALLPSTMNCM DVKTTNLTSG QYLSRFLANT TFRGLSGSIK
460 470 480 490 500
VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR LGSWQGGRIV MDSGIWPEQA
510 520 530 540 550
QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG QLCLDPMTND
560 570 580 590 600
SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV
610 620 630 640 650
GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS
660 670 680 690 700
TSLGILVRTR DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP
710 720 730 740 750
FGMTPKGRNR NKVFSFSSAL NVCYALLFGR TAAIKPPKCW TGRFLMNLWA
760 770 780 790 800
IFCMFCLSTY TANLAAVMVG EKIYEELSGI HDPKLHHPSQ GFRFGTVRES
810 820 830 840 850
SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD AFIMDKALLD
860 870 880 890 900
YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM
910 920 930 940 950
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI
960 970 980 990 1000
GEHIVYRLLL PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV
1010 1020 1030 1040 1050
EKRSNMGPQQ LMVWNTSNLS HDNQRKYIFN DEEGQNQLGT QTHQDIPLPP
1060 1070 1080 1090 1100
RRRELPASLT TNGKADSLNV ARNSVMQELS ELEKQIQVIR QELQLAVSRK
1110
TELEEYQRTN RTCES
Length:1,115
Mass (Da):125,105
Last modified:February 20, 2007 - v1
Checksum:iC10145036DF07774
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqiNP_001028523.1. NM_001033351.2.
UniGeneiMm.440095.

Genome annotation databases

EnsembliENSMUST00000076674; ENSMUSP00000075970; ENSMUSG00000039579.
GeneIDi242443.
KEGGimmu:242443.
UCSCiuc008swe.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqiNP_001028523.1. NM_001033351.2.
UniGeneiMm.440095.

3D structure databases

ProteinModelPortaliA2AIR4.
SMRiA2AIR4. Positions 143-941.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075970.

Proteomic databases

MaxQBiA2AIR4.
PaxDbiA2AIR4.
PRIDEiA2AIR4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000076674; ENSMUSP00000075970; ENSMUSG00000039579.
GeneIDi242443.
KEGGimmu:242443.
UCSCiuc008swe.3. mouse.

Organism-specific databases

CTDi116443.
MGIiMGI:1933206. Grin3a.

Phylogenomic databases

eggNOGiNOG320645.
GeneTreeiENSGT00760000119186.
HOGENOMiHOG000231528.
HOVERGENiHBG052634.
KOiK05213.
TreeFamiTF314731.

Miscellaneous databases

ChiTaRSiGrin3a. mouse.
NextBioi385347.
SOURCEiSearch...

Gene expression databases

BgeeiA2AIR4.
ExpressionAtlasiA2AIR4. baseline and differential.
GenevisibleiA2AIR4. MM.

Family and domain databases

InterProiIPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AIR4_MOUSE
AccessioniPrimary (citable) accession number: A2AIR4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 22, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.