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A2AIR4

- A2AIR4_MOUSE

UniProt

A2AIR4 - A2AIR4_MOUSE

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Protein
Submitted name:

Protein Grin3a

Gene
Grin3a
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium channel activity Source: MGI
  2. extracellular-glutamate-gated ion channel activity Source: RefGenome
  3. glycine binding Source: Ensembl
  4. neurotransmitter binding Source: Ensembl
  5. N-methyl-D-aspartate selective glutamate receptor activity Source: MGI
  6. protein binding Source: MGI

GO - Biological processi

  1. calcium ion transmembrane transport Source: GOC
  2. calcium ion transport Source: MGI
  3. dendrite development Source: MGI
  4. ion transmembrane transport Source: GOC
  5. prepulse inhibition Source: MGI
  6. response to ethanol Source: Ensembl
  7. rhythmic process Source: Ensembl
  8. synaptic transmission, glutamatergic Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotations, ReceptorSAAS annotations

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Grin3aImported
Gene namesi
Name:Grin3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:1933206. Grin3a.

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. dendrite Source: RefGenome
  3. neuronal cell body Source: MGI
  4. N-methyl-D-aspartate selective glutamate receptor complex Source: RefGenome
  5. postsynaptic membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotations, Membrane, Postsynaptic cell membraneSAAS annotations, Synapse

PTM / Processingi

Proteomic databases

PaxDbiA2AIR4.
PRIDEiA2AIR4.

Expressioni

Gene expression databases

ArrayExpressiA2AIR4.

Structurei

3D structure databases

ProteinModelPortaliA2AIR4.
SMRiA2AIR4. Positions 143-497, 512-952.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

eggNOGiNOG320645.
GeneTreeiENSGT00740000115410.
HOGENOMiHOG000231528.
HOVERGENiHBG052634.
KOiK05213.
TreeFamiTF314731.

Family and domain databases

InterProiIPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
IPR001638. SBP_bac_3.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
PF00497. SBP_bac_3. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AIR4-1 [UniParc]FASTAAdd to Basket

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MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV     50
GAVHLQPWTT APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS 100
ALHGRGPPGS RKLGEGAGTE TLWPRDALLF AVENLNRVEG LLPYNLSLEV 150
VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF LQSVCHTVVV QGVSALLAFP 200
QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL SLENSLSSDA 250
DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN 300
LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP 350
DLHWVLGDSQ NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV 400
ATATMIQPEL ALLPSTMNCM DVKTTNLTSG QYLSRFLANT TFRGLSGSIK 450
VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR LGSWQGGRIV MDSGIWPEQA 500
QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG QLCLDPMTND 550
SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV 600
GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS 650
TSLGILVRTR DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP 700
FGMTPKGRNR NKVFSFSSAL NVCYALLFGR TAAIKPPKCW TGRFLMNLWA 750
IFCMFCLSTY TANLAAVMVG EKIYEELSGI HDPKLHHPSQ GFRFGTVRES 800
SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD AFIMDKALLD 850
YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM 900
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI 950
GEHIVYRLLL PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV 1000
EKRSNMGPQQ LMVWNTSNLS HDNQRKYIFN DEEGQNQLGT QTHQDIPLPP 1050
RRRELPASLT TNGKADSLNV ARNSVMQELS ELEKQIQVIR QELQLAVSRK 1100
TELEEYQRTN RTCES 1115
Length:1,115
Mass (Da):125,105
Last modified:February 20, 2007 - v1
Checksum:iC10145036DF07774
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqiNP_001028523.1. NM_001033351.2.
UniGeneiMm.440095.

Genome annotation databases

EnsembliENSMUST00000076674; ENSMUSP00000075970; ENSMUSG00000039579.
GeneIDi242443.
KEGGimmu:242443.
UCSCiuc008swe.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL732521 Genomic DNA. No translation available.
AL807392 Genomic DNA. No translation available.
RefSeqi NP_001028523.1. NM_001033351.2.
UniGenei Mm.440095.

3D structure databases

ProteinModelPortali A2AIR4.
SMRi A2AIR4. Positions 143-497, 512-952.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi A2AIR4.
PRIDEi A2AIR4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000076674 ; ENSMUSP00000075970 ; ENSMUSG00000039579 .
GeneIDi 242443.
KEGGi mmu:242443.
UCSCi uc008swe.2. mouse.

Organism-specific databases

CTDi 116443.
MGIi MGI:1933206. Grin3a.

Phylogenomic databases

eggNOGi NOG320645.
GeneTreei ENSGT00740000115410.
HOGENOMi HOG000231528.
HOVERGENi HBG052634.
KOi K05213.
TreeFami TF314731.

Miscellaneous databases

NextBioi 385347.
SOURCEi Search...

Gene expression databases

ArrayExpressi A2AIR4.

Family and domain databases

InterProi IPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
IPR001638. SBP_bac_3.
[Graphical view ]
Pfami PF00060. Lig_chan. 1 hit.
PF00497. SBP_bac_3. 1 hit.
[Graphical view ]
PRINTSi PR00177. NMDARECEPTOR.
SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view ]
SUPFAMi SSF53822. SSF53822. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AIR4_MOUSE
AccessioniPrimary (citable) accession number: A2AIR4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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