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A2AIR4

- A2AIR4_MOUSE

UniProt

A2AIR4 - A2AIR4_MOUSE

Protein
Submitted name:

Protein Grin3a

Gene

Grin3a

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium channel activity Source: MGI
    2. extracellular-glutamate-gated ion channel activity Source: RefGenome
    3. glycine binding Source: Ensembl
    4. neurotransmitter binding Source: Ensembl
    5. N-methyl-D-aspartate selective glutamate receptor activity Source: MGI
    6. protein binding Source: MGI

    GO - Biological processi

    1. calcium ion transmembrane transport Source: GOC
    2. calcium ion transport Source: MGI
    3. dendrite development Source: MGI
    4. ion transmembrane transport Source: GOC
    5. prepulse inhibition Source: MGI
    6. response to ethanol Source: Ensembl
    7. rhythmic process Source: Ensembl
    8. synaptic transmission, glutamatergic Source: RefGenome

    Keywords - Molecular functioni

    Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Grin3aImported
    Gene namesi
    Name:Grin3aImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:1933206. Grin3a.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. dendrite Source: RefGenome
    3. neuronal cell body Source: MGI
    4. N-methyl-D-aspartate selective glutamate receptor complex Source: RefGenome
    5. postsynaptic membrane Source: MGI

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

    PTM / Processingi

    Proteomic databases

    PaxDbiA2AIR4.
    PRIDEiA2AIR4.

    Expressioni

    Gene expression databases

    ArrayExpressiA2AIR4.

    Structurei

    3D structure databases

    ProteinModelPortaliA2AIR4.
    SMRiA2AIR4. Positions 143-497, 512-952.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    eggNOGiNOG320645.
    GeneTreeiENSGT00740000115410.
    HOGENOMiHOG000231528.
    HOVERGENiHBG052634.
    KOiK05213.
    TreeFamiTF314731.

    Family and domain databases

    InterProiIPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view]
    PfamiPF00060. Lig_chan. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view]
    PRINTSiPR00177. NMDARECEPTOR.
    SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view]
    SUPFAMiSSF53822. SSF53822. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A2AIR4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRRLSLWWLL SRVCLLLPPP CALVLAGVPS SSSHPQPCQI LKRIGHAVRV     50
    GAVHLQPWTT APRAASRAQD GGRAGAQRDE PESGTWRPPA PSQGARWLGS 100
    ALHGRGPPGS RKLGEGAGTE TLWPRDALLF AVENLNRVEG LLPYNLSLEV 150
    VMAIEAGLGD LPLMPFSSPS SPWSSDPFSF LQSVCHTVVV QGVSALLAFP 200
    QSQGEMMELD LVSSVLHIPV LSIVRHEFPR ESQNPLHLQL SLENSLSSDA 250
    DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTENNSKFH LESIINITAN 300
    LSSTKDLLSF LQVQLENIRN STPTMVMFGC DMGSIRQIFE MSTQFGLSPP 350
    DLHWVLGDSQ NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV 400
    ATATMIQPEL ALLPSTMNCM DVKTTNLTSG QYLSRFLANT TFRGLSGSIK 450
    VKGSTIVSSE NNFFIWNLQY DPMGKPMWTR LGSWQGGRIV MDSGIWPEQA 500
    QRHKTHFHHP NKLHLRVVTL IEHPFVFTRE VDDEGLCPAG QLCLDPMTND 550
    SSILDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEQLAED MNFDFDLYIV 600
    GDGKYGAWKN GHWTGLVGDL LSGTANMAVT SFSINTARSQ VIDFTSPFFS 650
    TSLGILVRTR DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP 700
    FGMTPKGRNR NKVFSFSSAL NVCYALLFGR TAAIKPPKCW TGRFLMNLWA 750
    IFCMFCLSTY TANLAAVMVG EKIYEELSGI HDPKLHHPSQ GFRFGTVRES 800
    SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD AFIMDKALLD 850
    YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM 900
    DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI 950
    GEHIVYRLLL PRIKNKSKLQ YWLHTSQRFH RALNTSFVEE KQPCSKTKRV 1000
    EKRSNMGPQQ LMVWNTSNLS HDNQRKYIFN DEEGQNQLGT QTHQDIPLPP 1050
    RRRELPASLT TNGKADSLNV ARNSVMQELS ELEKQIQVIR QELQLAVSRK 1100
    TELEEYQRTN RTCES 1115
    Length:1,115
    Mass (Da):125,105
    Last modified:February 20, 2007 - v1
    Checksum:iC10145036DF07774
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL732521 Genomic DNA. No translation available.
    AL807392 Genomic DNA. No translation available.
    RefSeqiNP_001028523.1. NM_001033351.2.
    UniGeneiMm.440095.

    Genome annotation databases

    EnsembliENSMUST00000076674; ENSMUSP00000075970; ENSMUSG00000039579.
    GeneIDi242443.
    KEGGimmu:242443.
    UCSCiuc008swe.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL732521 Genomic DNA. No translation available.
    AL807392 Genomic DNA. No translation available.
    RefSeqi NP_001028523.1. NM_001033351.2.
    UniGenei Mm.440095.

    3D structure databases

    ProteinModelPortali A2AIR4.
    SMRi A2AIR4. Positions 143-497, 512-952.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi A2AIR4.
    PRIDEi A2AIR4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000076674 ; ENSMUSP00000075970 ; ENSMUSG00000039579 .
    GeneIDi 242443.
    KEGGi mmu:242443.
    UCSCi uc008swe.2. mouse.

    Organism-specific databases

    CTDi 116443.
    MGIi MGI:1933206. Grin3a.

    Phylogenomic databases

    eggNOGi NOG320645.
    GeneTreei ENSGT00740000115410.
    HOGENOMi HOG000231528.
    HOVERGENi HBG052634.
    KOi K05213.
    TreeFami TF314731.

    Miscellaneous databases

    NextBioi 385347.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi A2AIR4.

    Family and domain databases

    InterProi IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view ]
    Pfami PF00060. Lig_chan. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view ]
    PRINTSi PR00177. NMDARECEPTOR.
    SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53822. SSF53822. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2AIR4_MOUSE
    AccessioniPrimary (citable) accession number: A2AIR4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3