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Protein
Submitted name:

Cadherin EGF LAG seven-pass G-type receptor 2

Gene

Celsr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cerebrospinal fluid secretion Source: MGI
  • cilium assembly Source: MGI
  • cilium movement Source: MGI
  • neuron migration Source: MGI
  • regulation of protein localization Source: MGI
  • ventricular system development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin EGF LAG seven-pass G-type receptor 2Imported
Gene namesi
Name:Celsr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1858235. Celsr2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiA2AFR6.
ExpressionAtlasiA2AFR6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000088046.

Structurei

3D structure databases

ProteinModelPortaliA2AFR6.
SMRiA2AFR6. Positions 9-50, 52-210.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118805.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
[Graphical view]
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2AFR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FLFLPGCPTK KIVCDSSICH NGGTCVNQWN AFSCECPLGF GGKSCAQEMA
60 70 80 90 100
NPQRFLGSSL VAWHGLSLPI SQPWHLSLMF RTRQADGVLL QAVTRGRSTI
110 120 130 140 150
TLQLRAGHVV LSVEGTGLQA SSLRLEPGRA NDGDWHHAQL ALGASGGPGH
160 170 180 190 200
AILSFDYGQQ KAEGNLGPRL HGLHLSNITV GGVPGPASGV ARGFRGCLQG
210
VRVSETPEGI SSLDPSRGE
Length:219
Mass (Da):23,015
Last modified:February 20, 2007 - v1
Checksum:i51FFCE78D142B869
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei219 – 2191Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671899 Genomic DNA. No translation available.
AL672200 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000147565; ENSMUSP00000122516; ENSMUSG00000068740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671899 Genomic DNA. No translation available.
AL672200 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA2AFR6.
SMRiA2AFR6. Positions 9-50, 52-210.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000088046.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000147565; ENSMUSP00000122516; ENSMUSG00000068740.

Organism-specific databases

MGIiMGI:1858235. Celsr2.

Phylogenomic databases

GeneTreeiENSGT00760000118805.

Miscellaneous databases

ChiTaRSiCelsr2. mouse.
NextBioi35543235.
SOURCEiSearch...

Gene expression databases

BgeeiA2AFR6.
ExpressionAtlasiA2AFR6. baseline and differential.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
[Graphical view]
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AFR6_MOUSE
AccessioniPrimary (citable) accession number: A2AFR6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: June 24, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.