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A2AFR6

- A2AFR6_MOUSE

UniProt

A2AFR6 - A2AFR6_MOUSE

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Protein
Submitted name:

Cadherin EGF LAG seven-pass G-type receptor 2

Gene

Celsr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. cerebrospinal fluid secretion Source: MGI
  2. cilium assembly Source: MGI
  3. cilium movement Source: MGI
  4. neuron migration Source: MGI
  5. regulation of protein localization Source: MGI
  6. ventricular system development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin EGF LAG seven-pass G-type receptor 2Imported
Gene namesi
Name:Celsr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 3

Organism-specific databases

MGIiMGI:1858235. Celsr2.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiA2AFR6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA2AFR6.
SMRiA2AFR6. Positions 9-50, 52-210.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118805.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
[Graphical view]
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2AFR6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
FLFLPGCPTK KIVCDSSICH NGGTCVNQWN AFSCECPLGF GGKSCAQEMA
60 70 80 90 100
NPQRFLGSSL VAWHGLSLPI SQPWHLSLMF RTRQADGVLL QAVTRGRSTI
110 120 130 140 150
TLQLRAGHVV LSVEGTGLQA SSLRLEPGRA NDGDWHHAQL ALGASGGPGH
160 170 180 190 200
AILSFDYGQQ KAEGNLGPRL HGLHLSNITV GGVPGPASGV ARGFRGCLQG
210
VRVSETPEGI SSLDPSRGE
Length:219
Mass (Da):23,015
Last modified:February 20, 2007 - v1
Checksum:i51FFCE78D142B869
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei219 – 2191Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671899 Genomic DNA. No translation available.
AL672200 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000147565; ENSMUSP00000122516; ENSMUSG00000068740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671899 Genomic DNA. No translation available.
AL672200 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A2AFR6.
SMRi A2AFR6. Positions 9-50, 52-210.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000147565 ; ENSMUSP00000122516 ; ENSMUSG00000068740 .

Organism-specific databases

MGIi MGI:1858235. Celsr2.

Phylogenomic databases

GeneTreei ENSGT00760000118805.

Miscellaneous databases

ChiTaRSi Celsr2. mouse.
NextBioi 35543235.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi A2AFR6. baseline and differential.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
[Graphical view ]
Pfami PF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 1 hit.
[Graphical view ]
SMARTi SM00181. EGF. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
PROSITEi PS00010. ASX_HYDROXYL. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2AFR6_MOUSE
AccessioniPrimary (citable) accession number: A2AFR6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 26, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3