A2AFR6 (A2AFR6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cadherin EGF LAG seven-pass G-type receptor 2 Ensembl ENSMUSP00000122516

Gene names

Name:

Celsr2 Ensembl ENSMUSP00000122516 MGI 1858235

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000122516

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	219 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000122516

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS000152
PTM	Disulfide bond SAAS SAAS001791
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cerebrospinal fluid secretion Inferred from genetic interaction PubMed 20473291. Source: MGI cilium assembly Inferred from mutant phenotype PubMed 20473291. Source: MGI cilium movement Inferred from mutant phenotype PubMed 20473291. Source: MGI neuron migration Inferred from mutant phenotype PubMed 20631168. Source: MGI regulation of protein localization Inferred from mutant phenotype PubMed 20473291. Source: MGI ventricular system development Inferred from mutant phenotype PubMed 21746835. Source: MGI
Cellular_component	plasma membrane Inferred from sequence orthology PubMed 19474315. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSMUSP00000122516
	Non-terminal residue	219	1	Ensembl ENSMUSP00000122516

Sequences

	Sequence		Length	Mass (Da)
	A2AFR6 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 51FFCE78D142B869	FASTA	219	23,015
	10 20 30 40 50 60 FLFLPGCPTK KIVCDSSICH NGGTCVNQWN AFSCECPLGF GGKSCAQEMA NPQRFLGSSL 70 80 90 100 110 120 VAWHGLSLPI SQPWHLSLMF RTRQADGVLL QAVTRGRSTI TLQLRAGHVV LSVEGTGLQA 130 140 150 160 170 180 SSLRLEPGRA NDGDWHHAQL ALGASGGPGH AILSFDYGQQ KAEGNLGPRL HGLHLSNITV 190 200 210 GGVPGPASGV ARGFRGCLQG VRVSETPEGI SSLDPSRGE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000122516.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000122516.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL671899 Genomic DNA. No translation available. AL672200 Genomic DNA. No translation available.
IPI	IPI00649549.
UniGene	Mm.39728.
3D structure databases
ProteinModelPortal	A2AFR6.
SMR	A2AFR6. Positions 9-50, 52-210.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000147565; ENSMUSP00000122516; ENSMUSG00000068740.
Organism-specific databases
MGI	MGI:1858235. Celsr2.
Phylogenomic databases
GeneTree	ENSGT00700000104170.
InParanoid	A2AFR6.
Gene expression databases
ArrayExpress	A2AFR6.
Family and domain databases
Gene3D	2.60.120.200. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR000742. EG-like_dom. IPR013032. EGF-like_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR001791. Laminin_G. [Graphical view]
Pfam	PF00008. EGF. 1 hit. PF02210. Laminin_G_2. 1 hit. [Graphical view]
SMART	SM00181. EGF. 1 hit. SM00282. LamG. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS00010. ASX_HYDROXYL. 1 hit. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 1 hit. PS50025. LAM_G_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35543235.
SOURCE	Search...

Entry information

Entry name

A2AFR6_MOUSE

Accession

Primary (citable) accession number: A2AFR6

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)