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A2AFR6

- A2AFR6_MOUSE

UniProt

A2AFR6 - A2AFR6_MOUSE

Protein
Submitted name:

Cadherin EGF LAG seven-pass G-type receptor 2

Gene

Celsr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. cerebrospinal fluid secretion Source: MGI
    2. cilium assembly Source: MGI
    3. cilium movement Source: MGI
    4. neuron migration Source: MGI
    5. regulation of protein localization Source: MGI
    6. ventricular system development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cadherin EGF LAG seven-pass G-type receptor 2Imported
    Gene namesi
    Name:Celsr2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:1858235. Celsr2.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: MGI

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiA2AFR6.

    Structurei

    3D structure databases

    ProteinModelPortaliA2AFR6.
    SMRiA2AFR6. Positions 9-50, 52-210.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    EGF-like domainUniRule annotationSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117340.
    InParanoidiA2AFR6.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR001791. Laminin_G.
    [Graphical view]
    PfamiPF00008. EGF. 1 hit.
    PF02210. Laminin_G_2. 1 hit.
    [Graphical view]
    SMARTiSM00181. EGF. 1 hit.
    SM00282. LamG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
    PS00022. EGF_1. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS50026. EGF_3. 1 hit.
    PS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    A2AFR6-1 [UniParc]FASTAAdd to Basket

    « Hide

    FLFLPGCPTK KIVCDSSICH NGGTCVNQWN AFSCECPLGF GGKSCAQEMA    50
    NPQRFLGSSL VAWHGLSLPI SQPWHLSLMF RTRQADGVLL QAVTRGRSTI 100
    TLQLRAGHVV LSVEGTGLQA SSLRLEPGRA NDGDWHHAQL ALGASGGPGH 150
    AILSFDYGQQ KAEGNLGPRL HGLHLSNITV GGVPGPASGV ARGFRGCLQG 200
    VRVSETPEGI SSLDPSRGE 219
    Length:219
    Mass (Da):23,015
    Last modified:February 20, 2007 - v1
    Checksum:i51FFCE78D142B869
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei219 – 2191Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671899 Genomic DNA. No translation available.
    AL672200 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000147565; ENSMUSP00000122516; ENSMUSG00000068740.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671899 Genomic DNA. No translation available.
    AL672200 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali A2AFR6.
    SMRi A2AFR6. Positions 9-50, 52-210.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000147565 ; ENSMUSP00000122516 ; ENSMUSG00000068740 .

    Organism-specific databases

    MGIi MGI:1858235. Celsr2.

    Phylogenomic databases

    GeneTreei ENSGT00750000117340.
    InParanoidi A2AFR6.

    Miscellaneous databases

    NextBioi 35543235.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi A2AFR6.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR001791. Laminin_G.
    [Graphical view ]
    Pfami PF00008. EGF. 1 hit.
    PF02210. Laminin_G_2. 1 hit.
    [Graphical view ]
    SMARTi SM00181. EGF. 1 hit.
    SM00282. LamG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS00010. ASX_HYDROXYL. 1 hit.
    PS00022. EGF_1. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS50026. EGF_3. 1 hit.
    PS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2AFR6_MOUSE
    AccessioniPrimary (citable) accession number: A2AFR6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3