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A2AEM2

- A2AEM2_MOUSE

UniProt

A2AEM2 - A2AEM2_MOUSE

Protein
Submitted name:

Chloride channel CLIC-like 1, isoform CRA_a

Gene

Clcc1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chloride channel activity Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Chloride channel CLIC-like 1, isoform CRA_aImported
    Submitted name:
    Chloride channel CLIC-like protein 1Imported
    Gene namesi
    Name:Clcc1Imported
    ORF Names:mCG_4070Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:2385186. Clcc1.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. Golgi apparatus Source: Ensembl
    3. nucleus Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000016611.
    HOGENOMiHOG000231351.
    HOVERGENiHBG060364.
    InParanoidiA2AEM2.
    OMAiSWTYKDD.
    OrthoDBiEOG7B8S3V.
    TreeFamiTF328890.

    Family and domain databases

    InterProiIPR009231. Chloride_chnl_CLIC-like.
    [Graphical view]
    PfamiPF05934. MCLC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2AEM2-1 [UniParc]FASTAAdd to Basket

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    MALFRMLCRL LLCECLLLIT GYAHDDDWID PTDMLNYDAA SGTMRKSQVR    50
    SGTSEKKEVS PDSSEAEELS DCLHRLDSLT HKVDSCEKKK MKDYESQSNP 100
    VFRRYLNKIL IEAGKLGLPD ENKVEMRYDA EILLSRQTLL EIQKFLSGEE 150
    WKPGALDDAL SDILINFKCH DSEAWKWQFE DYFGVDPYNV FMVLLCLLCL 200
    VVLVATELWT YVRWYTQMKR IFIISFLLSL AWNWIYLYKM AFAQHQANIA 250
    GMEPFDNLCA KKMDWTGSLW EWFTSSWTYK DDPCQKYYEL LIVNPIWLVP 300
    PTKALAITFT NFVTEPLKHI GKGAGEFIKA LMKEIPVLLQ IPVLAILALA 350
    VLSFCYGAGR SVPMLRHFGG PDREPPRALE PDDRRRQKGL DYRLHGGAGD 400
    ADFSYRGPAG SIEQGPYDKM HASKRDALRQ RFHSGNKSPE VLRAFDLPDT 450
    EAQEHPEVVP SHKSPIMNTN LETGELPGES TPTEYSQSAK DVSGQVPSAG 500
    KSSPTVDKAQ LKTDSECSPP GGCPPSKEAA VAAHGTEPVS SPCG 544
    Length:544
    Mass (Da):61,240
    Last modified:February 20, 2007 - v1
    Checksum:i36ED907AB5EE1B42
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671917 Genomic DNA. No translation available.
    AL683823 Genomic DNA. No translation available.
    CH466607 Genomic DNA. Translation: EDL01978.1.
    CH466607 Genomic DNA. Translation: EDL01981.1.
    RefSeqiNP_001171241.1. NM_001177770.1.
    UniGeneiMm.214545.

    Genome annotation databases

    EnsembliENSMUST00000106613; ENSMUSP00000102224; ENSMUSG00000027884.
    GeneIDi229725.
    KEGGimmu:229725.
    UCSCiuc008qzn.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671917 Genomic DNA. No translation available.
    AL683823 Genomic DNA. No translation available.
    CH466607 Genomic DNA. Translation: EDL01978.1 .
    CH466607 Genomic DNA. Translation: EDL01981.1 .
    RefSeqi NP_001171241.1. NM_001177770.1.
    UniGenei Mm.214545.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000106613 ; ENSMUSP00000102224 ; ENSMUSG00000027884 .
    GeneIDi 229725.
    KEGGi mmu:229725.
    UCSCi uc008qzn.2. mouse.

    Organism-specific databases

    CTDi 23155.
    MGIi MGI:2385186. Clcc1.

    Phylogenomic databases

    GeneTreei ENSGT00390000016611.
    HOGENOMi HOG000231351.
    HOVERGENi HBG060364.
    InParanoidi A2AEM2.
    OMAi SWTYKDD.
    OrthoDBi EOG7B8S3V.
    TreeFami TF328890.

    Miscellaneous databases

    NextBioi 379649.
    SOURCEi Search...

    Family and domain databases

    InterProi IPR009231. Chloride_chnl_CLIC-like.
    [Graphical view ]
    Pfami PF05934. MCLC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    6. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2AEM2_MOUSE
    AccessioniPrimary (citable) accession number: A2AEM2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3