A2ADB4 (A2ADB4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Chloride channel protein ClC-Ka Ensembl ENSMUSP00000122396

Gene names

Name:

Clcnka Ensembl ENSMUSP00000122396 MGI 1329026

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000122396

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	192 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000122396

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of body fluid levels Inferred from mutant phenotype PubMed 11133517. Source: MGI renal inner medulla development Inferred from mutant phenotype PubMed 11423561. Source: MGI
Cellular_component	basolateral plasma membrane Inferred from direct assay PubMed 11423561. Source: MGI
Molecular_function	voltage-gated chloride channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	192	1	Ensembl ENSMUSP00000122396

Sequences

	Sequence		Length	Mass (Da)
	A2ADB4 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: E15C561170D076C5	FASTA	192	21,173
	10 20 30 40 50 60 MEELVGLREG SSGKPVTLQE LWGPCPRIRR GIRGGLEWLK ERLFRAREDW YFLVALGVLM 70 80 90 100 110 120 ALISYAMNFA IGRVVRAHKW LYREVGDGHL LRYLSWTVYP VALLSFSSGF SQSITPFSGG 130 140 150 160 170 180 SGLPELKTML SGVVLENYLD IKNFGAKVVG LSCTLATGST IFLGKVGPFV HLSVMISAYL 190 GRVRAKAVGD TE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000122396.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000122396.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL670285 Genomic DNA. No translation available.
IPI	IPI00648958.
UniGene	Mm.167900.
3D structure databases
ProteinModelPortal	A2ADB4.
SMR	A2ADB4. Positions 50-184.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000133676; ENSMUSP00000122396; ENSMUSG00000033770.
Organism-specific databases
MGI	MGI:1329026. Clcnka.
Phylogenomic databases
GeneTree	ENSGT00620000087869.
InParanoid	A2ADB4.
Gene expression databases
ArrayExpress	A2ADB4.
Family and domain databases
Gene3D	1.10.3080.10. 1 hit.
InterPro	IPR014743. Cl-channel_core. IPR001807. Cl-channel_volt-gated. IPR002250. Cl_channel-K. [Graphical view]
Pfam	PF00654. Voltage_CLC. 1 hit. [Graphical view]
PRINTS	PR00762. CLCHANNEL. PR01119. CLCHANNELKDY.
SUPFAM	SSF81340. Cl-channel_core. 1 hit.
ProtoNet	Search...
Other
NextBio	35543063.
SOURCE	Search...

Entry information

Entry name

A2ADB4_MOUSE

Accession

Primary (citable) accession number: A2ADB4

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)