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A2AD37

- A2AD37_MOUSE

UniProt

A2AD37 - A2AD37_MOUSE

Protein
Submitted name:

Opioid receptor, delta 1

Gene

Oprd1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. enkephalin receptor activity Source: Ensembl
    2. opioid receptor activity Source: MGI

    GO - Biological processi

    1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: MGI
    2. adult locomotory behavior Source: MGI
    3. cellular response to growth factor stimulus Source: Ensembl
    4. neuropeptide signaling pathway Source: MGI
    5. phospholipase C-activating G-protein coupled receptor signaling pathway Source: Ensembl
    6. protein import into nucleus, translocation Source: Ensembl
    7. regulation of calcium ion transport Source: Ensembl
    8. regulation of sensory perception of pain Source: Ensembl

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Opioid receptor, delta 1Imported
    Gene namesi
    Name:Oprd1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97438. Oprd1.

    Subcellular locationi

    GO - Cellular componenti

    1. axon terminus Source: Ensembl
    2. cytoplasm Source: Ensembl
    3. dendrite membrane Source: Ensembl
    4. integral component of membrane Source: MGI
    5. intrinsic component of plasma membrane Source: Ensembl
    6. membrane Source: MGI
    7. membrane raft Source: Ensembl
    8. postsynaptic membrane Source: Ensembl
    9. vesicle Source: Ensembl

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriA2AD37.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG106919.
    InParanoidiA2AD37.
    KOiK04213.
    OMAiLCRKPCG.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000321. Delta_opi_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001418. Opioid_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00525. DELTAOPIOIDR.
    PR00237. GPCRRHODOPSN.
    PR00384. OPIOIDR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2AD37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELVPSARAE LQSSPLVNLS DAFPSAFPSA GANASGSPGA RSASSLALAI    50
    AITALYSAVC AVGLLGNVLV MFGIVRYTKL KTATNIYIFN LALADALATS 100
    TLPFQSAKYL METWPFGELL CKAVLSIDYY NMFTSIFTLT MMSVDRYIAV 150
    CHPVKALDFR TPAKAKLINI CIWVLASGVG VPIMVMAVTQ PRDGAVVCML 200
    QFPSPSWYWD TVTKICVFLF AFVVPILIIT VCYGLMLLRL RSVRLLSGSK 250
    EKDRSLRRIT RMVLVVVGAF VVCWAPIHIF VIVWTLVDIN RRDPLVVAAL 300
    HLCIALGYAN SSLNPVLYAF LDENFKRCFR QLCRTPCGRQ EPGSLRRPRQ 350
    ATTRERVTAC TPSDGPGGGA AA 372
    Length:372
    Mass (Da):40,561
    Last modified:February 20, 2007 - v1
    Checksum:iBC3B3BBD2E52D3F9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC137958 mRNA. Translation: AAI37959.1.
    BC137969 mRNA. Translation: AAI37970.1.
    RefSeqiNP_038650.3. NM_013622.3.
    UniGeneiMm.5243.

    Genome annotation databases

    GeneIDi18386.
    KEGGimmu:18386.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC137958 mRNA. Translation: AAI37959.1 .
    BC137969 mRNA. Translation: AAI37970.1 .
    RefSeqi NP_038650.3. NM_013622.3.
    UniGenei Mm.5243.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 18386.
    KEGGi mmu:18386.

    Organism-specific databases

    CTDi 4985.
    MGIi MGI:97438. Oprd1.

    Phylogenomic databases

    HOVERGENi HBG106919.
    InParanoidi A2AD37.
    KOi K04213.
    OMAi LCRKPCG.

    Miscellaneous databases

    NextBioi 293976.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori A2AD37.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000321. Delta_opi_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001418. Opioid_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00525. DELTAOPIOIDR.
    PR00237. GPCRRHODOPSN.
    PR00384. OPIOIDR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiA2AD37_MOUSE
    AccessioniPrimary (citable) accession number: A2AD37
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)