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Protein
Submitted name:

HLA class II histocompatibility antigen, DQ beta 1 chain

Gene

HLA-DQB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
HLA class II histocompatibility antigen, DQ beta 1 chainImported
Gene namesi
Name:HLA-DQB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:4944. HLA-DQB1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179344.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_500264221531 – 134Sequence analysisAdd BLAST104

Proteomic databases

MaxQBiA2AAY8.
PaxDbiA2AAY8.
PeptideAtlasiA2AAY8.
PRIDEiA2AAY8.

Expressioni

Gene expression databases

BgeeiENSG00000179344.
ExpressionAtlasiA2AAY8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA2AAY8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 127Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST89

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IWG3. Eukaryota.
ENOG410YI0S. LUCA.
GeneTreeiENSGT00760000118970.
HOGENOMiHOG000231206.
HOVERGENiHBG012730.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

A2AAY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPVEPT VTISPSRTEA
60 70 80 90 100
LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI RNGDWTFQIL
110 120 130
VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RLLH
Length:134
Mass (Da):15,195
Last modified:February 20, 2007 - v1
Checksum:iC7D1E5C5E042BF5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662789 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000399082; ENSP00000382032; ENSG00000179344.
UCSCiuc063nrf.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA2AAY8_HUMAN
AccessioniPrimary (citable) accession number: A2AAY8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 5, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported