Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A2AAJ9

- OBSCN_MOUSE

UniProt

A2AAJ9 - OBSCN_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Obscurin

Gene

Obscn

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle (By similarity).By similarity

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.By similarity

Cofactori

Magnesium.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei7444 – 74441ATPPROSITE-ProRule annotation
Active sitei7534 – 75341Proton acceptorBy similarity
Binding sitei8624 – 86241ATPPROSITE-ProRule annotation
Active sitei8714 – 87141Proton acceptorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7421 – 74299ATPBy similarityPROSITE-ProRule annotation
Nucleotide bindingi8601 – 86099ATPBy similarityPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
  3. Rho guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. multicellular organismal development Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Differentiation

Keywords - Ligandi

ATP-binding, Calmodulin-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Obscurin (EC:2.7.11.1)
Alternative name(s):
Obscurin-RhoGEF
Obscurin-myosin light chain kinase
Short name:
Obscurin-MLCK
Gene namesi
Name:ObscnImported
Synonyms:Gm878
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:2681862. Obscn.

Subcellular locationi

GO - Cellular componenti

  1. M band Source: BHF-UCL
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 88918891ObscurinPRO_0000296296Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi30 ↔ 81By similarityPROSITE-ProRule annotation
Disulfide bondi257 ↔ 309By similarityPROSITE-ProRule annotation
Disulfide bondi352 ↔ 402By similarityPROSITE-ProRule annotation
Disulfide bondi885 ↔ 935By similarityPROSITE-ProRule annotation
Disulfide bondi977 ↔ 1027By similarityPROSITE-ProRule annotation
Disulfide bondi1069 ↔ 1119By similarityPROSITE-ProRule annotation
Disulfide bondi1161 ↔ 1211By similarityPROSITE-ProRule annotation
Disulfide bondi1253 ↔ 1303By similarityPROSITE-ProRule annotation
Disulfide bondi1345 ↔ 1395By similarityPROSITE-ProRule annotation
Disulfide bondi1437 ↔ 1487By similarityPROSITE-ProRule annotation
Disulfide bondi1529 ↔ 1579By similarityPROSITE-ProRule annotation
Disulfide bondi1621 ↔ 1671By similarityPROSITE-ProRule annotation
Disulfide bondi1713 ↔ 1763By similarityPROSITE-ProRule annotation
Disulfide bondi1805 ↔ 1855By similarityPROSITE-ProRule annotation
Disulfide bondi1897 ↔ 1947By similarityPROSITE-ProRule annotation
Disulfide bondi1989 ↔ 2039By similarityPROSITE-ProRule annotation
Disulfide bondi2081 ↔ 2131By similarityPROSITE-ProRule annotation
Disulfide bondi2263 ↔ 2313By similarityPROSITE-ProRule annotation
Disulfide bondi2620 ↔ 2669By similarityPROSITE-ProRule annotation
Disulfide bondi2743 ↔ 2793By similarityPROSITE-ProRule annotation
Disulfide bondi2922 ↔ 2972By similarityPROSITE-ProRule annotation
Disulfide bondi3100 ↔ 3150By similarityPROSITE-ProRule annotation
Disulfide bondi3280 ↔ 3330By similarityPROSITE-ProRule annotation
Disulfide bondi3369 ↔ 3419By similarityPROSITE-ProRule annotation
Disulfide bondi3549 ↔ 3599By similarityPROSITE-ProRule annotation
Disulfide bondi3638 ↔ 3688By similarityPROSITE-ProRule annotation
Disulfide bondi3815 ↔ 3864By similarityPROSITE-ProRule annotation
Disulfide bondi3903 ↔ 3952By similarityPROSITE-ProRule annotation
Disulfide bondi4063 ↔ 4112By similarityPROSITE-ProRule annotation
Disulfide bondi4151 ↔ 4200By similarityPROSITE-ProRule annotation
Disulfide bondi4239 ↔ 4288By similarityPROSITE-ProRule annotation
Disulfide bondi4327 ↔ 4376By similarityPROSITE-ProRule annotation
Disulfide bondi4415 ↔ 4464By similarityPROSITE-ProRule annotation
Disulfide bondi4503 ↔ 4552By similarityPROSITE-ProRule annotation
Disulfide bondi4591 ↔ 4640By similarityPROSITE-ProRule annotation
Disulfide bondi4679 ↔ 4728By similarityPROSITE-ProRule annotation
Disulfide bondi4767 ↔ 4816By similarityPROSITE-ProRule annotation
Disulfide bondi4855 ↔ 4905By similarityPROSITE-ProRule annotation
Disulfide bondi4944 ↔ 4994By similarityPROSITE-ProRule annotation
Disulfide bondi5033 ↔ 5085By similarityPROSITE-ProRule annotation
Disulfide bondi5581 ↔ 5634By similarityPROSITE-ProRule annotation
Disulfide bondi5859 ↔ 5911By similarityPROSITE-ProRule annotation
Disulfide bondi6089 ↔ 6141By similarityPROSITE-ProRule annotation
Disulfide bondi6975 ↔ 7027By similarityPROSITE-ProRule annotation
Disulfide bondi7069 ↔ 7122By similarityPROSITE-ProRule annotation
Disulfide bondi8406 ↔ 8458By similarityPROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiA2AAJ9.
PaxDbiA2AAJ9.
PRIDEiA2AAJ9.

PTM databases

PhosphoSiteiA2AAJ9.

Expressioni

Gene expression databases

BgeeiA2AAJ9.
GenevestigatoriA2AAJ9.

Structurei

3D structure databases

ProteinModelPortaliA2AAJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 9991Ig-like 1Sequence AnalysisAdd
BLAST
Domaini109 – 20193Ig-like 2Sequence AnalysisAdd
BLAST
Domaini234 – 32087Ig-like 3Sequence AnalysisAdd
BLAST
Domaini329 – 41587Ig-like 4Sequence AnalysisAdd
BLAST
Domaini513 – 61098Fibronectin type-III 1PROSITE-ProRule annotationAdd
BLAST
Domaini702 – 79392Ig-like 5Sequence AnalysisAdd
BLAST
Domaini859 – 95193Ig-like 6Sequence AnalysisAdd
BLAST
Domaini951 – 104393Ig-like 7Sequence AnalysisAdd
BLAST
Domaini1043 – 113593Ig-like 8Sequence AnalysisAdd
BLAST
Domaini1135 – 122793Ig-like 9Sequence AnalysisAdd
BLAST
Domaini1227 – 131993Ig-like 10Sequence AnalysisAdd
BLAST
Domaini1319 – 140789Ig-like 11Sequence AnalysisAdd
BLAST
Domaini1411 – 150393Ig-like 12Sequence AnalysisAdd
BLAST
Domaini1503 – 159593Ig-like 13Sequence AnalysisAdd
BLAST
Domaini1595 – 168793Ig-like 14Sequence AnalysisAdd
BLAST
Domaini1687 – 177993Ig-like 15Sequence AnalysisAdd
BLAST
Domaini1779 – 187193Ig-like 16Sequence AnalysisAdd
BLAST
Domaini1871 – 196393Ig-like 17Sequence AnalysisAdd
BLAST
Domaini1963 – 205189Ig-like 18Sequence AnalysisAdd
BLAST
Domaini2055 – 214793Ig-like 19Sequence AnalysisAdd
BLAST
Domaini2152 – 224190Ig-like 20Sequence AnalysisAdd
BLAST
Domaini2242 – 232584Ig-like 21Sequence AnalysisAdd
BLAST
Domaini2329 – 241587Ig-like 22Sequence AnalysisAdd
BLAST
Domaini2420 – 250485Ig-like 23Sequence AnalysisAdd
BLAST
Domaini2598 – 268184Ig-like 24Sequence AnalysisAdd
BLAST
Domaini2721 – 281292Ig-like 25Sequence AnalysisAdd
BLAST
Domaini2900 – 298485Ig-like 26Sequence AnalysisAdd
BLAST
Domaini3078 – 316285Ig-like 27Sequence AnalysisAdd
BLAST
Domaini3258 – 334285Ig-like 28Sequence AnalysisAdd
BLAST
Domaini3348 – 343184Ig-like 29Sequence AnalysisAdd
BLAST
Domaini3527 – 361084Ig-like 30Sequence AnalysisAdd
BLAST
Domaini3616 – 370085Ig-like 31Sequence AnalysisAdd
BLAST
Domaini3785 – 387692Ig-like 32Sequence AnalysisAdd
BLAST
Domaini3881 – 396484Ig-like 33Sequence AnalysisAdd
BLAST
Domaini4041 – 412484Ig-like 34Sequence AnalysisAdd
BLAST
Domaini4129 – 421284Ig-like 35Sequence AnalysisAdd
BLAST
Domaini4218 – 430083Ig-like 36Sequence AnalysisAdd
BLAST
Domaini4306 – 438883Ig-like 37Sequence AnalysisAdd
BLAST
Domaini4394 – 447683Ig-like 38Sequence AnalysisAdd
BLAST
Domaini4482 – 456483Ig-like 39Sequence AnalysisAdd
BLAST
Domaini4570 – 465283Ig-like 40Sequence AnalysisAdd
BLAST
Domaini4658 – 474083Ig-like 41Sequence AnalysisAdd
BLAST
Domaini4745 – 482884Ig-like 42Sequence AnalysisAdd
BLAST
Domaini4832 – 491584Ig-like 43Sequence AnalysisAdd
BLAST
Domaini4922 – 500685Ig-like 44Sequence AnalysisAdd
BLAST
Domaini5012 – 510493Ig-like 45Sequence AnalysisAdd
BLAST
Domaini5374 – 546087Ig-like 46Sequence AnalysisAdd
BLAST
Domaini5467 – 556094Fibronectin type-III 2PROSITE-ProRule annotationAdd
BLAST
Domaini5553 – 565098Ig-like 47Sequence AnalysisAdd
BLAST
Domaini5812 – 584130IQPROSITE-ProRule annotationAdd
BLAST
Domaini5838 – 592184Ig-like 48Sequence AnalysisAdd
BLAST
Domaini6068 – 615790Ig-like 49Sequence AnalysisAdd
BLAST
Domaini6200 – 628990Ig-like 50Sequence AnalysisAdd
BLAST
Domaini6311 – 640797Ig-like 51Sequence AnalysisAdd
BLAST
Domaini6540 – 660768SH3Sequence AnalysisAdd
BLAST
Domaini6633 – 6817185DHPROSITE-ProRule annotationAdd
BLAST
Domaini6835 – 6944110PHPROSITE-ProRule annotationAdd
BLAST
Domaini6954 – 703784Ig-like 52Sequence AnalysisAdd
BLAST
Domaini7048 – 713891Ig-like 53Sequence AnalysisAdd
BLAST
Domaini7305 – 739389Ig-like 54Sequence AnalysisAdd
BLAST
Domaini7415 – 7668254Protein kinase 1PROSITE-ProRule annotationAdd
BLAST
Domaini8385 – 846985Ig-like 55Sequence AnalysisAdd
BLAST
Domaini8479 – 857193Fibronectin type-III 3PROSITE-ProRule annotationAdd
BLAST
Domaini8595 – 8847253Protein kinase 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 DH (DBL-homology) domain.PROSITE-ProRule annotation
Contains 3 fibronectin type-III domains.PROSITE-ProRule annotation
Contains 55 Ig-like (immunoglobulin-like) domains.Sequence Analysis
Contains 1 IQ domain.PROSITE-ProRule annotation
Contains 1 PH domain.PROSITE-ProRule annotation
Contains 2 protein kinase domains.PROSITE-ProRule annotation
Contains 1 SH3 domain.Sequence Analysis

Keywords - Domaini

Immunoglobulin domain, Repeat, SH3 domain

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000115256.
HOVERGENiHBG108206.
InParanoidiA2AAJ9.
PhylomeDBiA2AAJ9.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.10. 69 hits.
InterProiIPR000219. DH-domain.
IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR000048. IQ_motif_EF-hand-BS.
IPR011009. Kinase-like_dom.
IPR020682. Obscurin-myosin_light-ch_kin.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
IPR001452. SH3_domain.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PANTHERiPTHR19897:SF17. PTHR19897:SF17. 1 hit.
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 59 hits.
PF00612. IQ. 1 hit.
PF00069. Pkinase. 2 hits.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00060. FN3. 3 hits.
SM00409. IG. 20 hits.
SM00408. IGc2. 42 hits.
SM00015. IQ. 1 hit.
SM00233. PH. 1 hit.
SM00220. S_TKc. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF49265. SSF49265. 3 hits.
SSF50044. SSF50044. 1 hit.
SSF56112. SSF56112. 2 hits.
PROSITEiPS50010. DH_2. 1 hit.
PS50853. FN3. 3 hits.
PS50835. IG_LIKE. 54 hits.
PS50096. IQ. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 2 hits.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: A2AAJ9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDHSFSGAPR FLTRPKAFVV SVGKDATLSC QIVGNPTPHV SWEKDRQPVE
60 70 80 90 100
AGARFRLAQD GDVYRLTILD LALGDSGQYV CRARNAIGEA FAAVGLRVDS
110 120 130 140 150
EGTCAEQAPH FLLRPTSIRV REGADATFRC RVGGSPQPAV SWSKDGRRLG
160 170 180 190 200
PPDAPHVRVE EHGESSALRI RSARPRDGGT YEVRAENPLG SASAAAALVV
210 220 230 240 250
DSDAEVAGPP GTSTATLLAH LQQRREAMRA EGIPPSPPGA GTRTCTVTEG
260 270 280 290 300
KHARLSCFVT GEPKPETVWK KDGQLVTEGR RHVVYEDEQE NFVLKILFCK
310 320 330 340 350
QSDRGLYTCT ASNLVGQTYS SVLVVVREPT VPFKKRLQDL EVREKESATF
360 370 380 390 400
QCEVAQPATE AAWFKEETRL WASAKYDIEE EGTERRLTVR NVSADDDAVY
410 420 430 440 450
ICETTEGSRT VAELSVQGNL TRKLPRKTAV RTGDTAIFWV ELAVPEGPVR
460 470 480 490 500
WLRNQEEMVA GGRVAITAEG TCHTLTIFQC TLEDMGEVAF VSGGCRTTTQ
510 520 530 540 550
FCVSAPRRPP LYPPADPVVK AKTESSVTLS WSAPPHGDRP VTIDGYVLEK
560 570 580 590 600
RKLGAYAWSR CHEAGWLATT EFTITGVAEE GDFQFRVSAI NHFGQGPYLE
610 620 630 640 650
FPGTMHLVPM LAVKTPLKAV EAVEGGEVTF SVDLTVASSG EWFLDGEALK
660 670 680 690 700
ASSIYVIRCD RTRHMLTIRE VPARLHGAQL KFVANGIETS IQMVVRAALG
710 720 730 740 750
LPSSKLPAAA AREVLAQLHE EAQLLAELSD QAAAVTWLKD GRELSLGPKY
760 770 780 790 800
EMQVSAGRRA LLVRDVAQDD AGLYECVSRG SRTAYQLLVQ DITDGYRDWG
810 820 830 840 850
PAGPQKHMCK CAGAKIARYL GSSCYRFLQY DKGVWHWLEA ALDTRQGKGT
860 870 880 890 900
SSCSLHEKPK LVFAKGQQAH SEVKAEAGNS ATLSCEVTQA QTEVTWFKDG
910 920 930 940 950
KKLSSSSKVR MEASGCSRRL VVQQAGKADA GEYSCEAGGQ KLSFRLDVAE
960 970 980 990 1000
PKLVFAKGQQ AHSEVKAEAG ASATLSCEVA QAQTEVTWFK DGKKLSSSSK
1010 1020 1030 1040 1050
VRMEASGCSR RLVVQQAGKA DAGEYSCEAG GQKLSFRLDV AEPKMVFAKE
1060 1070 1080 1090 1100
QQARSEVKAE AGASATLSCE VAQAQTEVTW FKDGKKLSSS SKVRMEASGC
1110 1120 1130 1140 1150
SRRLVVQQAG KADAGEYSCE AGGQKLSFRL DVTEPKLVFA KEQQARSEVK
1160 1170 1180 1190 1200
AEVGNSATLS CEVAQAQTEV TWFKDGKKLS SSSKVRMEAS GCSRRLVVQQ
1210 1220 1230 1240 1250
AGKADAGEYS CEAGGQKLSF RLDVAEPKLV FAKEQQARSE VKAEAGNSAT
1260 1270 1280 1290 1300
LSCEVAQAQT EVTWFKDGKK LSSSSKVRME ASGCSRRLVV QQAGKADAGE
1310 1320 1330 1340 1350
YSCEAGGQKL SFHLDVTEPK LVFAKEQQAH SEVKAEAGAS ATLSCEVAQA
1360 1370 1380 1390 1400
QTEVTWFKDG KKLSSSSKVR MEASGCSRRL VVQQAGKADA GEYSCEAEGQ
1410 1420 1430 1440 1450
KLSFRLDVAE PKLVFAKEQQ ARSEVKAEAG ASATLSCEVA QAQTEVTWFK
1460 1470 1480 1490 1500
DGKKLSSSSK VRVEASGCSR RLVVQQAGKA DAGEYSCEAG GQKLSFRLDV
1510 1520 1530 1540 1550
AEPKLVFAKE QQANSEVKAE AGASATLSCE VAQAQTEVTW FKDGKKLSSS
1560 1570 1580 1590 1600
SKVRVEASGC SRRLVVQQAG KADAGEYSCE AGGQKLSFRL DVAEPKLAFA
1610 1620 1630 1640 1650
KEQQAHSEVK AEAGASATLS CEVAQAQTEV TWFKDGKKLS SSSKVRVEAS
1660 1670 1680 1690 1700
GCSRRLVVQQ AGKADAGEYS CEAGGQKLSF RLDVAEPKLA FAKEQQAHSE
1710 1720 1730 1740 1750
VKAEAGASAT LSCEVAQAQT EVTWFKDGKK LSSSSKVRVE ASGCSRRLVV
1760 1770 1780 1790 1800
QQAGKADAGE YSCEAGGQKL SFRLDVAEPK LAFAKEQQAH SEVKAEAGAS
1810 1820 1830 1840 1850
ATLSCEVAQA QTEVTWFKDG KKLSSSSKVR VEASGCSRRL VVQQAGKADA
1860 1870 1880 1890 1900
GEYSCEAGGQ KLFFRLDVAE PKLMFAKEQQ AHSEVKAEAG ASATLSCEVA
1910 1920 1930 1940 1950
QAQTEVTWFK DGKKLSSSSK VRVEASGCSR RLVVQQAGKA DAGEYSCEAG
1960 1970 1980 1990 2000
GQKLSFRLDV AEPKLVFAKE QQAHSEVKAE AGASATLSCE VAQAQTEVTW
2010 2020 2030 2040 2050
FKDGKKLSSS SKVRVEASGC SRRLVVQQVG KADAGEYSCE ARGQKLSFRL
2060 2070 2080 2090 2100
DVADTRLMFA KEQQARTEVK AEAGNSATLS CEVAQAQTEV TWFKDGKKLS
2110 2120 2130 2140 2150
SSSKVRVEAS GCSRRLVVQQ AGKADAGEYS CEAGGQKLSF RLDVAEAESQ
2160 2170 2180 2190 2200
IPERPSRREP LVVKEHETII LTATIAAPSV AAVTWLKDGV EIRRSKRHEA
2210 2220 2230 2240 2250
TSLGDTHTLT VRGAQVLDSA IYSCRVGKEG QDFPVQVEEV AAKFSKPLEP
2260 2270 2280 2290 2300
VEGELGGTVM LVCELSPEQA EVVWRCGNTQ LRPGKRFQMT SEGPRRTLTV
2310 2320 2330 2340 2350
SGLREDDAEE YVCESRDDRT SARLTVKVPR VVKFTSGLSA MVAEEGQEAT
2360 2370 2380 2390 2400
FQCVVSPSDA GVTWYKDGMQ LQPSEKFVMV ESGASRSLTI LGLTLEDAGQ
2410 2420 2430 2440 2450
VTVEAEGASS SAALRVREAP VLFKKKLEPQ TVEERTSVTL EVELTRPWPE
2460 2470 2480 2490 2500
VKWTRNAAVL TPSENVEIRA EGARHCLVLR SVGFADRGFF GCETPDDKTQ
2510 2520 2530 2540 2550
AKLNVEMRQV RLVRGLQEVE AKEQGTASMD VELSHAEVEG SWTRDGLRLQ
2560 2570 2580 2590 2600
PGPKCHLAVQ GPVHILTLSA LQPQDSGLVA FRAEGVHTSA RLIVTELPVS
2610 2620 2630 2640 2650
FTRVLQDVVA TQKEKVTLEC ELSRPVDVRW LKDGVELRAG KAIGIVAQGT
2660 2670 2680 2690 2700
CRSLVIYRCE TGDQGVYVCD ALDAQTSASL RVQGRTYTLI FRRVLAEDAG
2710 2720 2730 2740 2750
EVKFVAENAE SRAHLRVKEL PVTLLRPLRD KIAMEKHRGV LECQVSRASA
2760 2770 2780 2790 2800
QVRWFKGGVE LQSGPKYEVV SDGLYRKLVI NDVQPEDEDT YTCDAGNVKT
2810 2820 2830 2840 2850
SAQFFVEEQS ITIVRGLKDM TVMEPAPAWF ECETSIPSVR PPKWLLGKTV
2860 2870 2880 2890 2900
LQAGGNVGLE QDGTVHRLTL HKTCSTMTGP VHFTIGKSRS SAQLVVSDIP
2910 2920 2930 2940 2950
VVLTRPLEPK AGRELQSVVL SCDFRPAPKA VQWYKDDTPL SPSEKFKMAL
2960 2970 2980 2990 3000
EGQMAELRIL RLTPADAGVY RCQAGSAQSS AEVTVEAREV TVIQPLQDAE
3010 3020 3030 3040 3050
AMEEGRVCFS CELSHKDEDI EWSLNGTPLY NDSFHEISHE GCLHTLVLKS
3060 3070 3080 3090 3100
VRQADTGTVC ATSPKVSVSA RLVVKGKPVV FLKALDDVSA EERGTLTLQC
3110 3120 3130 3140 3150
EVSDPEARVV WRKDGVELGP SDKYDFLHKA GARGLTVHDL SHEDAGLYTC
3160 3170 3180 3190 3200
QVGSKETQSK VSVHDLHVGI TKRLKTVEVL EGESCSFECV LSHESPSDPA
3210 3220 3230 3240 3250
VWTVGGKTVG GSGHFHAVRQ GRKYTLTVKD AALSDAGEVV FSVLGLTSKA
3260 3270 3280 3290 3300
SLIIRERPVD ITKPLEDQRT TLGEDVMLSC ELSRAGTSVR WLKDGKAIRK
3310 3320 3330 3340 3350
SQKYDLLSEG TRAVLVVRKA SLKDSGEYTC ETEASKSTAK LCVEEKANRF
3360 3370 3380 3390 3400
TEELADLQVE EKGRAVFTCK TEHPASVVTW RKGLLELRAS GKHVPSQEGL
3410 3420 3430 3440 3450
TLKLTINALE RTDSDTYTCD IGQARTQARL LVHGQKVRVI EDLEDTAVQE
3460 3470 3480 3490 3500
GSSAKFCCRI APADYGPVHW FLDKTPLHSN ELNEITVQPG GYHVLTLRQL
3510 3520 3530 3540 3550
ALKDSGTVYF EAGDQRTSAA LRVTEKPSIF SRPLTDVTVT EGEDLTLVCE
3560 3570 3580 3590 3600
TTTVDSSVRW TKDGKTLRPS ARCQLSHEGC QAQLLITATT PQDGGRYKCE
3610 3620 3630 3640 3650
IGGASSSSIV RVHALPVRFR ESLKDVEVPE GKAATLRCVL SSVAAPVEWR
3660 3670 3680 3690 3700
HGDDVLKSSN KYSLRQEGAV LELVIRDLQP QDSGQYSCSF GDQTTSATLT
3710 3720 3730 3740 3750
VKTSSAQFVG KLRNKEATEG TTVTLRCELT KEAPVEWKKG TETLRNGDKY
3760 3770 3780 3790 3800
SLKQDGAVCE LQICSLLVAD AGEYSCVCGQ EKTSATLTVK ALLVHFVRRL
3810 3820 3830 3840 3850
RSKEATEGDT TTLQCELSKA APVEWRKGTE TLRDGDRYSL KQDGAVCELQ
3860 3870 3880 3890 3900
IRSLTIADAG EYLCTCGQEK TSATLTVRAL PAKFKDSLKN EEATEGTTAT
3910 3920 3930 3940 3950
LSCELSKAAP VTWKKGPKTL QSGDKYVLRQ DGAVCGLQIH GLTMADAGEY
3960 3970 3980 3990 4000
SCVCGQEKTS ATLTVRGLPA KFIEDLRSQE ATEGATAILR CELSKAAPVE
4010 4020 4030 4040 4050
WRKGSETLKD GDRYTLRQDG AVCELQIRGL AVVDTGTYSL PTKFTEGLRN
4060 4070 4080 4090 4100
EEATEGTMAT LRCQMSKAAP VEWRKGSETL RDGDRYSLRQ DGAMCELQIR
4110 4120 4130 4140 4150
GLTIEDSGEY TCVCGQEKTS ATLSVKALPS RFIEDLRSQE ATEGTMATLR
4160 4170 4180 4190 4200
CQMSKTAPVE WKKGSETLRD GGRYSLRQDG PVCELQICDL AVEDAGEYSC
4210 4220 4230 4240 4250
VCGQEKTSAT LSIKALPPRF IEDLRSQEAT EGTMATLRCQ MSKAAPVEWR
4260 4270 4280 4290 4300
KGSETLGDGG RYSLRQNGAV CELQIHDLAV EDTGEYSCVC GQEKTSATLN
4310 4320 4330 4340 4350
VKALPPRFIE DLRSQEATEG TMATLRCQMS KAAPVEWRKG SETLRDGGRY
4360 4370 4380 4390 4400
SLRQDGAVCE LQIHDLDVED AGQYSCVCGQ EKTSAVLTVD ALPPKFTEGL
4410 4420 4430 4440 4450
KKEEATEGTM VTLRCQMSKE ATVEWRKGAK TLSDGGRYSL RQDGAMCELQ
4460 4470 4480 4490 4500
ICGLAVEDAG EYSCVCGQEK TSATLSVKAL PPRFIEDLRS QEATEGTMAT
4510 4520 4530 4540 4550
LRCQMSKAAP VEWRKGSETL RDGDRYSLRQ DGAVCELQIR DLAVEDAGEY
4560 4570 4580 4590 4600
LCVCGQEKTS ATLSVKALPP RFIEDLRSQE ATEGTMATLR CQMSKAAPVE
4610 4620 4630 4640 4650
WRKGSKTLRD GDRYSLRQDG AMCELQICDL AVEDTGDYSC VCGQEKTSAT
4660 4670 4680 4690 4700
LSVKALPPRF IEDLRSQEAR EGTVATLRCR MSKAAPVEWR KGSETLKDGD
4710 4720 4730 4740 4750
RYSLRQEGNL CELQIRDLAV EDTEEYSCVC GQEKTSATLS VKALPAKFIE
4760 4770 4780 4790 4800
DLRSQEAPES STVTLRCKLS KKASVVWKKG SETLRNGARY SLRQDGAVCE
4810 4820 4830 4840 4850
LEIRDLTVED TGEYSCTCGQ ERTSATLSIM APQVVFQQPL QNLQAEEGSM
4860 4870 4880 4890 4900
ASLRCELSVP NAAMVWSKGG LELQGDTRRE ARQQGCVAEL LLRDLRREDA
4910 4920 4930 4940 4950
GEYSCTCGSQ TTSATLMVTA APVRFLRELQ AQDVDEGATA RLRCELSREA
4960 4970 4980 4990 5000
VSVEWRKGSL QLFPCAKYQM VQEGTTAELL VHGVEQEDAG EYTCDAGHTQ
5010 5020 5030 5040 5050
SIARLSVRAP KPKFKTDLQS TEQEAGGTAR LCCQLSEAEP GTPVQWLKEG
5060 5070 5080 5090 5100
VELHVGSKYE MRRQGAVCEL LIHGLEAKDT GEYACLVGGQ KTLASLRVKE
5110 5120 5130 5140 5150
PEVTIVRGLV DMEVQADEDV EFTCKVSQAG ATDVQWHLQG LPLQSNEVTE
5160 5170 5180 5190 5200
VAVLADGCTH VLQLKGVTLE DAGTVSFHVG GLSSSAQLTV RGDRSGAPEG
5210 5220 5230 5240 5250
CAAQRGPGCP LPVPTVQGLG PGGSLGFGRG SLAVQRDERH HCGAGHTLPA
5260 5270 5280 5290 5300
HSAQGDPGGC WDHHSPSGLM LLRGPAEGHS KNTVLRGLEN VDALEGGEAL
5310 5320 5330 5340 5350
FECQLSQPEV AAHTWLLDDE PVHTSEKVEV VYFENGLRHL LLLKNLKPQD
5360 5370 5380 5390 5400
SCRVTFLAGD VVTSAFLTVR GWRLEVLEPP HDASVKAGMQ VRFTCILSEA
5410 5420 5430 5440 5450
VPVGEATWYI NGAAIQPDDT DWTVTTDGSH HALTLSNAQP QHAGEVTFAA
5460 5470 5480 5490 5500
RDAVASARLS VLALPDPPED AEVVGRSDHS VTLSWVAPMS DGGGGLCGYR
5510 5520 5530 5540 5550
VEMKEASTGQ WQLCHDLVPG PECVVDDLVP GKTYRFRVAA VGPAGAGEPV
5560 5570 5580 5590 5600
HLPQMAPAPA PAPAPAPAPE TRQAVVGEDI CLELEVAADG GEVVWHKGTE
5610 5620 5630 5640 5650
RIQPGGHFEV LSRGQRQMLV IKGFRTEDQG EYRCGPIQGL PSSGAATFNV
5660 5670 5680 5690 5700
VMTSGSGDEV PAQPSLPPEA AQEGDLHLLW EALARKRRMS REPTLDSISE
5710 5720 5730 5740 5750
LPEEDSRVQH LRQEAEETAP DLSEGYSTAD ELARTGEADL SHTSSDDESR
5760 5770 5780 5790 5800
AGTPSLVTYL KKAGGPGISP LASKHEAQVT TSVKPQKQQE PVVPTCPPPG
5810 5820 5830 5840 5850
DLSAADLMDP SLDKAAVKIQ AAFKGYKVRK EMKQQEGPVF SRTFGDTEAQ
5860 5870 5880 5890 5900
VGDVLRLECV LATKTDMRAC WLKDGIELTD GRHYHIDQLK DGTCSLLVTG
5910 5920 5930 5940 5950
LAPTDSGRYT CQVSTKSGRV SHSACVVVSG TESEAESSSG GELDDAFRRA
5960 5970 5980 5990 6000
ARRLHRLFRT KSPAELSEEE LFLSADEGPG EPEEPADWQT YREDENFVCI
6010 6020 6030 6040 6050
RFESLAEARQ AVTCFRNMFA TMGIGVEISL GEQGPRGVEM RIGKVAPTVT
6060 6070 6080 6090 6100
PAVPLAKTPG LQTSDAAPVF LTELQNQDVQ DGYPMSFDCV VTGQPVPSVR
6110 6120 6130 6140 6150
WFKDGKLLEE DDHYMINEDQ QGGHQLIITA VVPADMGVYR CLAENSMGVS
6160 6170 6180 6190 6200
STKAELRVEL TSTDYDTAAD ATETSSYFSA QGYLSSREQE GTESDEGQLP
6210 6220 6230 6240 6250
QVLEELKDLQ VAPGTRLAKF QLKVKGYPAP KLYWFKDGQP LTTSDHIRMT
6260 6270 6280 6290 6300
DKKTLHTLEI VSVTREDSGQ YAAYISNAVG AAYSSARLLV RGPSEPEEKP
6310 6320 6330 6340 6350
ASDVHERLVP PRILEKFTPK KVKRGSSITF SVKVEGHPAP SVHWLKEEAE
6360 6370 6380 6390 6400
KGVLWIGPDT PGYTMASSSK QHSLVLLDVG RQHQGTYTCI ATNPAGQALC
6410 6420 6430 6440 6450
SASLHISGLA KEEEQERVKE ALISSFLQGT SQAVSAQMSE SAGFADLVGQ
6460 6470 6480 6490 6500
SKGESLVAEE AHSHLSLAEV GTEEFLQKLT SQITEMVSAK ISQAKLQVPG
6510 6520 6530 6540 6550
GDSDEETKTP SASPRHGRSR PSSSVQESSS ESEDGDSRGE IFDIYVVTAD
6560 6570 6580 6590 6600
YLPLGAEQDA IILREGQYVE VLDSAHPLRW LVRTKPTKSS PSRQGWVSPA
6610 6620 6630 6640 6650
YLDKRLKLSP EWGPTEAPEF PGEAVSEDEY RTRLSSVIQE LLSSEQAFVG
6660 6670 6680 6690 6700
ELQFLESHHM KHLERSPRVP AAVASQKTVI FRNVQDISHF HSSFLKELQG
6710 6720 6730 6740 6750
CGTDDDVAMC FIKNQEAFEK YLEFLVGRVQ AESVVVSTPV QEFYKKYAEE
6760 6770 6780 6790 6800
TLSAKDPTQP PPPPLQHYLE QPVERVQKYQ ALLKELIRNK ARNRQNCALL
6810 6820 6830 6840 6850
EQAYAVVSAL PQRAENKLHV SLMENYPGTL EALGEPIRQG HFIVWEGAPG
6860 6870 6880 6890 6900
ARMPWKGHNR HVFLFRNYLV ICKPRRDSRT DTFSYVFRNM MKLSSIDLND
6910 6920 6930 6940 6950
QVEGDDRAFE VWHEREDSVR KYLLQARTVI IKNSWVKEIC GIQQRLAQPV
6960 6970 6980 6990 7000
WRPPEFEEEL ADCTAELGET VKLACRVTGT PKPIVSWYKD GKPVEVDPHH
7010 7020 7030 7040 7050
ILIEDPDGSC TLILDNLTGI DSGQYMCFAA SAAGNASTLG KILVQVPPRF
7060 7070 7080 7090 7100
VNKVRATPFV EGEDAQITCT VEGAPYPQIR WYKDGTLLAP GNRYRMLNEP
7110 7120 7130 7140 7150
RSGVLVLVIQ AASKEDLGHY ECELVNRLGS TRGGGELYMQ SPALRARDQH
7160 7170 7180 7190 7200
HREQIVAAVE VCSHDTSVEG SAHSAQDGAD QQAASVLWRL LGSEALGPSP
7210 7220 7230 7240 7250
GDLPNTRQSE PPAFEEAASQ IPGAASGTPG ELPEVSQPGT HKGLEQETTS
7260 7270 7280 7290 7300
SGSQGWTVPI RVEGTAWPGA GTGQLLLDVH SQVIMETTQR TYVCQAPDTG
7310 7320 7330 7340 7350
VTRAPSMQVT IEDVQVQVGD MAQFDAVIEG HPPPIVTWYK GSTQLTSSAR
7360 7370 7380 7390 7400
LSQRQDGTTY SLVLTDVAPH DAGVYTCVAN NAGGQVLCKA ELLVHGGDKL
7410 7420 7430 7440 7450
DAENQVYRRK LHSFYDVQEE IGRGVFGFVK RVQHKGNKMF CAAKFIPLRS
7460 7470 7480 7490 7500
KTRAQAYQER DILATLGHPL VTGLLDQFET RKTLILILEL CSSEELLDRL
7510 7520 7530 7540 7550
FKKGVVTEAE VKVYIQQLVE GLHYLHSHGI LHLDIKPPNI LMVHPAREDI
7560 7570 7580 7590 7600
KICDFGFAQK ITPSEPQYSK YGSPEFVSPE IIEQNPVSEG SDIWAMGVIS
7610 7620 7630 7640 7650
YLSLTCSSPF AGESDRATLL NVLEGRVSWS SPTAAHLSED AKDFIKATLQ
7660 7670 7680 7690 7700
RTPRARPSTS QCLAHPWFLK SMPAEEAHFI NTKQLKFLLA RSRWQRSLMS
7710 7720 7730 7740 7750
YKSILVMRSI PELLQGPPDS PSLGVARHLR GEASGASSSS SSSDNELAPF
7760 7770 7780 7790 7800
ARAKSLPPSP VTHSPLLHPR GFLRPSASLP EETEASMPTA DAAVPASPQS
7810 7820 7830 7840 7850
AGPPASPGCV PRHSVISSLF YQQAGEGAER GNKTSGAKRH PARRRHLLKG
7860 7870 7880 7890 7900
GYIARALPGL REPLMEYSLL EEEAAREEQA SLMTKTPSFE TALRLPSSSV
7910 7920 7930 7940 7950
REVPGRSHSL DNPPVTTGPS PEACKEQLLF PPSTGLTHET TAKDRGHKEG
7960 7970 7980 7990 8000
FLQESVPFPP MSGDSRPGKQ EGSSQDSCRG KPASSCHSEL GSGSQEGCGP
8010 8020 8030 8040 8050
PSSQSLGSLP PQSLKKELST SCGPLFSEQP QAAPFPTQVS PLLGSEKEPQ
8060 8070 8080 8090 8100
DGSLSEGPVP VPSSSPGSAS QVDASLDTEG LSEAGDTCDF TPPPQRPQEQ
8110 8120 8130 8140 8150
ATTRKFSLES RGGYAGVAGY GTFAFGGDAG GMLGQGPLWA RMAWAVSQSS
8160 8170 8180 8190 8200
EEQDEAATES PQPLESLGPI AEASGVPLRT SPSLTPWEEV EQVSLVQIRD
8210 8220 8230 8240 8250
LSGDAEAADT ISLDISEVDP AYLNLSDLYD IKYLPFEFMI FRRVPKPIEQ
8260 8270 8280 8290 8300
PESPGSETEA GQGLADFLEE AAWPWPGELG LRAGLEITEE PEEPGDLEAL
8310 8320 8330 8340 8350
LGEAAVGRKR KWSPSRGLFQ FPGRCLSGEE PVELGLRQRV KASMAHISRI
8360 8370 8380 8390 8400
LKGRPEGPER EGPPRKKAGL ASFRLSGLKG RDQAPSFLRE LSDEAVVLGQ
8410 8420 8430 8440 8450
SVTLACQVLA QPTAQATWSK DGVLLESSGH LLISSTLKNF QLLTILVVKE
8460 8470 8480 8490 8500
EDLGTYTCCV SNPLGTAVTT GVLRKAERPS SSPRPEVGEL YKDAVLLVWK
8510 8520 8530 8540 8550
PVESCGPVTY IVQCCIEGGS WTTLASDISD CCYLTGKLSR GGMYIFRTAC
8560 8570 8580 8590 8600
VSKAGMGPYS SPSEQVLLGG PNHLASEEES SRGRPAQLLP STKTFAFQMQ
8610 8620 8630 8640 8650
IRRGRFSVVR QCREKASGRA LAAKIVPYQP EDKTAVLREY EALKRLHHPH
8660 8670 8680 8690 8700
LAQLHAAYLS PRHLVLILEL CSGPELLPSL AERESYSESD VKDYLWQMLS
8710 8720 8730 8740 8750
ATQYLHAQHI LHLDLRSENM MVTEYNLLKV IDLGNAQSLD QEKVPAPENF
8760 8770 8780 8790 8800
KDYLETMAPE LLEGQGAVPQ TDIWAIGVTA FIMLSGEYPE SSEGTRDLQK
8810 8820 8830 8840 8850
GLRKGLIRLS RCYAGLSGGA VAFLQSSLCA QPWGRPCAST CLQCGWLTEE
8860 8870 8880 8890
GPTGSRPTPV TFPTVRLRAF VREREKRRAL LYKKHNLAQV R
Length:8,891
Mass (Da):966,372
Last modified:July 24, 2007 - v2
Checksum:i384E04B56A54CAB0
GO
Isoform 21 Publication (identifier: A2AAJ9-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     7161-7167: VCSHDTS → ERRPSPP
     7168-8891: Missing.

Note: Lacks the kinase domain. No experimental confirmation available.Curated

Show »
Length:7,167
Mass (Da):779,862
Checksum:iB61FCAB243F9EA4F
GO
Isoform 31 Publication (identifier: A2AAJ9-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-7306: Missing.
     8384-8389: Missing.

Show »
Length:1,579
Mass (Da):171,680
Checksum:i536554014AD05993
GO

Sequence cautioni

The sequence CAM24490.2 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAM24491.3 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAQ51661.2 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti7654 – 76541R → Q in AAT80900. (PubMed:15185077)Curated
Sequence conflicti8518 – 85181G → E in AAT80900. (PubMed:15185077)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 73067306Missing in isoform 3. 1 PublicationVSP_052486Add
BLAST
Alternative sequencei7161 – 71677VCSHDTS → ERRPSPP in isoform 2. 1 PublicationVSP_052485
Alternative sequencei7168 – 88911724Missing in isoform 2. 1 PublicationVSP_052487Add
BLAST
Alternative sequencei8384 – 83896Missing in isoform 3. 1 PublicationVSP_052488

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY603754 mRNA. Translation: AAT80900.1.
AL645854, AL662809 Genomic DNA. Translation: CAQ51661.2. Sequence problems.
AL662809, AL645854 Genomic DNA. Translation: CAM24490.2. Sequence problems.
AL662809, AL645854 Genomic DNA. Translation: CAM24491.3. Sequence problems.
BC044882 mRNA. Translation: AAH44882.2.
UniGeneiMm.339542.

Genome annotation databases

UCSCiuc029rlw.1. mouse. [A2AAJ9-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY603754 mRNA. Translation: AAT80900.1 .
AL645854 , AL662809 Genomic DNA. Translation: CAQ51661.2 . Sequence problems.
AL662809 , AL645854 Genomic DNA. Translation: CAM24490.2 . Sequence problems.
AL662809 , AL645854 Genomic DNA. Translation: CAM24491.3 . Sequence problems.
BC044882 mRNA. Translation: AAH44882.2 .
UniGenei Mm.339542.

3D structure databases

ProteinModelPortali A2AAJ9.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

PTM databases

PhosphoSitei A2AAJ9.

Proteomic databases

MaxQBi A2AAJ9.
PaxDbi A2AAJ9.
PRIDEi A2AAJ9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc029rlw.1. mouse. [A2AAJ9-1 ]

Organism-specific databases

MGIi MGI:2681862. Obscn.

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000115256.
HOVERGENi HBG108206.
InParanoidi A2AAJ9.
PhylomeDBi A2AAJ9.

Enzyme and pathway databases

Reactomei REACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Miscellaneous databases

PROi A2AAJ9.
SOURCEi Search...

Gene expression databases

Bgeei A2AAJ9.
Genevestigatori A2AAJ9.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.10. 69 hits.
InterProi IPR000219. DH-domain.
IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR000048. IQ_motif_EF-hand-BS.
IPR011009. Kinase-like_dom.
IPR020682. Obscurin-myosin_light-ch_kin.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
IPR001452. SH3_domain.
IPR008266. Tyr_kinase_AS.
[Graphical view ]
PANTHERi PTHR19897:SF17. PTHR19897:SF17. 1 hit.
Pfami PF00041. fn3. 2 hits.
PF07679. I-set. 59 hits.
PF00612. IQ. 1 hit.
PF00069. Pkinase. 2 hits.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SMARTi SM00060. FN3. 3 hits.
SM00409. IG. 20 hits.
SM00408. IGc2. 42 hits.
SM00015. IQ. 1 hit.
SM00233. PH. 1 hit.
SM00220. S_TKc. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
SSF49265. SSF49265. 3 hits.
SSF50044. SSF50044. 1 hit.
SSF56112. SSF56112. 2 hits.
PROSITEi PS50010. DH_2. 1 hit.
PS50853. FN3. 3 hits.
PS50835. IG_LIKE. 54 hits.
PS50096. IQ. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 2 hits.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases."
    Sutter S.B., Raeker M.O., Borisov A.B., Russell M.W.
    Dev. Genes Evol. 214:352-359(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6772-8891 (ISOFORM 2).
    Strain: FVB/N.
    Tissue: Salivary gland.
  4. "The mouse kinome: discovery and comparative genomics of all mouse protein kinases."
    Caenepeel S., Charydczak G., Sudarsanam S., Hunter T., Manning G.
    Proc. Natl. Acad. Sci. U.S.A. 101:11707-11712(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiOBSCN_MOUSE
AccessioniPrimary (citable) accession number: A2AAJ9
Secondary accession number(s): A2AB85
, B2FDE7, Q695L2, Q811H7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: October 29, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3