Reviewed, UniProtKB/Swiss-Prot A2AA28 (CQ095_MOUSE)

Names and origin

Protein names	Recommended name:     UPF0563 protein C17orf95 homolog
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the UPF0563 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 253	253	UPF0563 protein C17orf95 homolog		PRO_0000321521
Regions
	Transmembrane	62 – 79	18	Potential
Experimental info
	Sequence conflict	42	1	V → G in AAH26936. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	A2AA28-1 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: EEE3B9D8F1CDB4EB	FASTA	253	28,289
	10 20 30 40 50 60 MDSVRPRAPW APPPDPASLD SPTCEPGLMA GTQLFRFREE PVPGGNRAVL EVRVPQVLHV 70 80 90 100 110 120 QYGMYVWPCA VVLAQYLWFH RRSLPGKAVL EVGAGVSLPG ILAAKCGAKV ILSDSSEFPH 130 140 150 160 170 180 CLDICRQSCQ MNNLPQVEVV GLTWGHISKD ILSLPPQDII LGSDVFFEPE DFESILATVY 190 200 210 220 230 240 FLMQKNPKVQ FWSTYQVRSA DWSLEGLLYK WDMKCVHIPL ESFDADKEDI AESTLPGRHT 250 VEMLIISFAK DSF

References

[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Czech II. Tissue: Mammary tumor.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 22-253. Strain: C57BL/6J.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL645542 Genomic DNA. Translation: CAM25282.1. BC026936 mRNA. Translation: AAH26936.1. Different initiation. AK003450 mRNA. Translation: BAB22797.1. Different initiation.
IPI	IPI00133803.
RefSeq	NP_083141.3.
UniGene	Mm.348004
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A2AA28.
Proteomic databases
PRIDE	A2AA28.
Genome annotation databases
Ensembl	ENSMUST00000106370; ENSMUSP00000101978; ENSMUSG00000020815; Mus musculus. [Genome view]
GeneID	74319.
KEGG	mmu:74319.
NMPDR	fig|10090.3.peg.25692.
Organism-specific databases
MGI	MGI:1921569. 1110005A03Rik.
Phylogenomic databases
HOGENOM	HBG715351.
HOVERGEN	A2AA28.
InParanoid	A2AA28.
OMA	RVPQVLH.
OrthoDB	EOG983GQV.
Gene expression databases
Bgee	A2AA28.
CleanEx	MM_1110005A03RIK.
Genevestigator	A2AA28.
Family and domain databases
InterPro	IPR019410. Methyltransferase-16_put. [Graphical view]
Pfam	PF10294. Methyltransf_16. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	340441.

Entry information

Entry name

CQ095_MOUSE

Accession

Primary (citable) accession number: A2AA28
Secondary accession number(s): Q8R2Z2, Q9D1J5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	February 20, 2007
Last modified:	December 15, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)