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Protein
Submitted name:

Homeo box B8

Gene

Hoxb8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeo box B8Imported
Submitted name:
Homeobox B8Imported
Submitted name:
Hoxb8 proteinImported
Gene namesi
Name:Hoxb8Imported
ORF Names:mCG_3803Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96189. Hoxb8.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000056648.
ExpressionAtlasiA2A9Z8. baseline and differential.

Structurei

3D structure databases

SMRiA2A9Z8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 204Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the Antp homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489. Eukaryota.
ENOG410ZTBY. LUCA.
HOVERGENiHBG016849.
KOiK09308.
OMAiAGGTFQH.
OrthoDBiEOG091G09XD.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR000047. HTH_motif.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
PR00031. HTHREPRESSR.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A2A9Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH
60 70 80 90 100
PSQIQEFYHG PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ
110 120 130 140 150
DPDLVQYADC KLAAASGLGE EAEGSEQSPS PTQLFPWMRP QAAAGRRRGR
160 170 180 190 200
QTYSRYQTLE LEKEFLFNPY LTRKRRIEVS HALGLTERQV KIWFQNRRMK
210 220 230 240
WKKENNKDKF PSSKCEQEEL EKEKLERAPE TAEQGDAQKG DKK
Length:243
Mass (Da):27,618
Last modified:February 20, 2007 - v1
Checksum:i368964C77884D21F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139209 mRNA. Translation: AAI39210.1.
BC139212 mRNA. Translation: AAI39213.1.
CH466556 Genomic DNA. Translation: EDL16023.1.
RefSeqiNP_034591.1. NM_010461.2.
XP_017169784.1. XM_017314295.1.
XP_017169785.1. XM_017314296.1.
XP_017169786.1. XM_017314297.1.
UniGeneiMm.4822.

Genome annotation databases

GeneIDi15416.
KEGGimmu:15416.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA2A9Z8_MOUSE
AccessioniPrimary (citable) accession number: A2A9Z8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 5, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)