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Protein
Submitted name:

Homeo box B8

Gene

Hoxb8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeo box B8Imported
Submitted name:
Homeobox B8Imported
Submitted name:
Hoxb8 proteinImported
Gene namesi
Name:Hoxb8Imported
ORF Names:mCG_3803Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96189. Hoxb8.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000056648.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052496.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini144 – 20461Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the Antp homeobox family.SAAS annotation
Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489. Eukaryota.
ENOG410ZTBY. LUCA.
HOVERGENiHBG016849.
KOiK09308.
OMAiAGGTFQH.
OrthoDBiEOG091G09XD.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR000047. HTH_motif.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
PR00031. HTHREPRESSR.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2A9Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH
60 70 80 90 100
PSQIQEFYHG PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ
110 120 130 140 150
DPDLVQYADC KLAAASGLGE EAEGSEQSPS PTQLFPWMRP QAAAGRRRGR
160 170 180 190 200
QTYSRYQTLE LEKEFLFNPY LTRKRRIEVS HALGLTERQV KIWFQNRRMK
210 220 230 240
WKKENNKDKF PSSKCEQEEL EKEKLERAPE TAEQGDAQKG DKK
Length:243
Mass (Da):27,618
Last modified:February 20, 2007 - v1
Checksum:i368964C77884D21F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139209 mRNA. Translation: AAI39210.1.
BC139212 mRNA. Translation: AAI39213.1.
CH466556 Genomic DNA. Translation: EDL16023.1.
RefSeqiNP_034591.1. NM_010461.2.
UniGeneiMm.4822.

Genome annotation databases

GeneIDi15416.
KEGGimmu:15416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139209 mRNA. Translation: AAI39210.1.
BC139212 mRNA. Translation: AAI39213.1.
CH466556 Genomic DNA. Translation: EDL16023.1.
RefSeqiNP_034591.1. NM_010461.2.
UniGeneiMm.4822.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052496.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15416.
KEGGimmu:15416.

Organism-specific databases

CTDi3218.
MGIiMGI:96189. Hoxb8.

Phylogenomic databases

eggNOGiKOG0489. Eukaryota.
ENOG410ZTBY. LUCA.
HOVERGENiHBG016849.
KOiK09308.
OMAiAGGTFQH.
OrthoDBiEOG091G09XD.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000056648.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR000047. HTH_motif.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
PR00031. HTHREPRESSR.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA2A9Z8_MOUSE
AccessioniPrimary (citable) accession number: A2A9Z8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.