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A2A934

- A2A934_MOUSE

UniProt

A2A934 - A2A934_MOUSE

Protein
Submitted name:

PR domain zinc finger protein 16

Gene

Prdm16

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metal ion binding Source: InterPro
    2. nucleic acid binding Source: InterPro
    3. SMAD binding Source: MGI

    GO - Biological processi

    1. negative regulation of transforming growth factor beta receptor signaling pathway Source: MGI
    2. neurogenesis Source: MGI
    3. palate development Source: MGI
    4. somatic stem cell maintenance Source: MGI
    5. tongue development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PR domain zinc finger protein 16Imported
    Gene namesi
    Name:Prdm16Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:1917923. Prdm16.

    PTM / Processingi

    Proteomic databases

    PRIDEiA2A934.

    Structurei

    3D structure databases

    ProteinModelPortaliA2A934.
    SMRiA2A934. Positions 66-250, 281-445, 948-1058.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00530000063676.
    HOGENOMiHOG000231144.
    HOVERGENiHBG005619.

    Family and domain databases

    Gene3Di3.30.160.60. 8 hits.
    InterProiIPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00096. zf-C2H2. 4 hits.
    [Graphical view]
    SMARTiSM00317. SET. 1 hit.
    SM00355. ZnF_C2H2. 10 hits.
    [Graphical view]
    PROSITEiPS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2A934-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSKARARKL AKSDGDVVNN MYEPDPDLLA GQSAEEETED GILSPIPMGP     50
    PSPFPTSEDF TPKEGSPYEA PVYIPEDIPI PPDFELRESS IPGAGLGIWA 100
    KRKMEIGERF GPYVVTPRAA LKEADFGWEQ MLTDTEVSSQ ESCIKKQISE 150
    DLGSEKFCVD ANQAGSGSWL KYIRVACSCD DQNLAMCQIN EQIYYKVIKD 200
    IEPGEELLVH VKEGAYSLGV MAPSLDEDPT FRCDECDELF QCRLDLRRHK 250
    KYACSSAGAQ LYEGLGEELK PEGLGVGSDG QAHECKDCER MFPNKYSLEQ 300
    HMIVHTEERE YKCDQCPKAF NWKSNLIRHQ MSHDSGKRFE CENCVKVFTD 350
    PSNLQRHIRS QHVGARAHAC PDCGKTFATS SGLKQHKHIH STVKPFICEV 400
    CHKSYTQFSN LCRHKRMHAD CRTQIKCKDC GQMFSTTSSL NKHRRFCEGK 450
    NHYTPGSIFT PGLPLTPSPM MDKTKPSPTL NHGGLGFSEY FPSRPHPGSL 500
    PFSAAPPAFP ALTPGFPGIF PPSLYPRPPL LPPTPLLKSP LNHAQDAKLP 550
    SPLGNPALPL VSAVSNSSQG ATAATGSEEK FDGRLEDAYA EKVKNRSPDM 600
    SDGSDFEDIN TTTGTDLDTT TGTGSDLDSD LDSDRDKGKD KGKPVESKPE 650
    FGGASVPPGA MNSVAEVPAF YSQHSFFPPP EEQLLTASGA AGDSIKAIAS 700
    IAEKYFGPGF MSMQEKKLGS LPYHSVFPFQ FLPNFPHSLY PFTDRALAHN 750
    LLVKAEPKSP RDALKVGGPS AECPFDLTTK PKEAKPALLA PKVPLIPSSG 800
    EEQPLDLSIG SRARASQNGG GREPRKNHVY GERKPGVSEG LPKVCPAQLP 850
    QQPSLHYAKP SPFFMDPIYR VEKRKVADPV GVLKEKYLRP SPLLFHPQMS 900
    AIETMTEKLE SFAAMKADSG SSLQPLPHHP FNFRSPPPTL SDPILRKGKE 950
    RYTCRYCGKI FPRSANLTRH LRTHTGEQPY RCKYCDRSFS ISSNLQRHVR 1000
    NIHNKEKPFK CHLCNRCFGQ QTNLDRHLKK HEHEGAPVSQ HSGVLTNHLG 1050
    TSASSPTSES DNHALLDEKE DSYFSEIRNF IANSEMNQAS TRMDKRPEIQ 1100
    DLDSNPPCPG SASAKPEDVE EEEEEELEEE DDDSLAGKSQ EDTVSPTPEP 1150
    QGVYEDEEDE EPPSLTMGFD HTRRHMQ 1177
    Length:1,177
    Mass (Da):130,340
    Last modified:February 5, 2008 - v1
    Checksum:iFFBC17FCD168C29F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL611950 Genomic DNA. No translation available.
    AL627123 Genomic DNA. No translation available.
    AL627127 Genomic DNA. No translation available.
    AL627226 Genomic DNA. No translation available.
    RefSeqiNP_001171466.1. NM_001177995.1.
    UniGeneiMm.257785.

    Genome annotation databases

    EnsembliENSMUST00000105636; ENSMUSP00000101261; ENSMUSG00000039410.
    GeneIDi70673.
    KEGGimmu:70673.
    UCSCiuc008wbw.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL611950 Genomic DNA. No translation available.
    AL627123 Genomic DNA. No translation available.
    AL627127 Genomic DNA. No translation available.
    AL627226 Genomic DNA. No translation available.
    RefSeqi NP_001171466.1. NM_001177995.1.
    UniGenei Mm.257785.

    3D structure databases

    ProteinModelPortali A2A934.
    SMRi A2A934. Positions 66-250, 281-445, 948-1058.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A2A934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000105636 ; ENSMUSP00000101261 ; ENSMUSG00000039410 .
    GeneIDi 70673.
    KEGGi mmu:70673.
    UCSCi uc008wbw.1. mouse.

    Organism-specific databases

    CTDi 63976.
    MGIi MGI:1917923. Prdm16.

    Phylogenomic databases

    GeneTreei ENSGT00530000063676.
    HOGENOMi HOG000231144.
    HOVERGENi HBG005619.

    Miscellaneous databases

    ChiTaRSi PRDM16. mouse.
    NextBioi 332055.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 3.30.160.60. 8 hits.
    InterProi IPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00096. zf-C2H2. 4 hits.
    [Graphical view ]
    SMARTi SM00317. SET. 1 hit.
    SM00355. ZnF_C2H2. 10 hits.
    [Graphical view ]
    PROSITEi PS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2A934_MOUSE
    AccessioniPrimary (citable) accession number: A2A934
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3