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A2A931

- A2A931_MOUSE

UniProt

A2A931 - A2A931_MOUSE

Protein
Submitted name:

PR domain zinc finger protein 16

Gene

Prdm16

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metal ion binding Source: InterPro
    2. nucleic acid binding Source: InterPro
    3. SMAD binding Source: MGI

    GO - Biological processi

    1. negative regulation of transforming growth factor beta receptor signaling pathway Source: MGI
    2. neurogenesis Source: MGI
    3. palate development Source: MGI
    4. somatic stem cell maintenance Source: MGI
    5. tongue development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PR domain zinc finger protein 16Imported
    Gene namesi
    Name:Prdm16Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:1917923. Prdm16.

    PTM / Processingi

    Proteomic databases

    PRIDEiA2A931.

    Structurei

    3D structure databases

    ProteinModelPortaliA2A931.
    SMRiA2A931. Positions 25-209, 279-443, 946-1056.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00530000063676.
    HOGENOMiHOG000231144.
    HOVERGENiHBG005619.

    Family and domain databases

    Gene3Di3.30.160.60. 8 hits.
    InterProiIPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00096. zf-C2H2. 4 hits.
    [Graphical view]
    SMARTiSM00317. SET. 1 hit.
    SM00355. ZnF_C2H2. 10 hits.
    [Graphical view]
    PROSITEiPS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2A931-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSKARARKL AKSDGDVVNN MYEPDPDLLA GQSAEEETED GILSPIPMGP     50
    PSPFPTSEDF TPKEGSPYEA PVYIPEDIPI PPDFELRESS IPGAGLGIWA 100
    KRKMEIGERF GPYVVTPRAA LKEADFGWEM LTDTEVSSQE SCIKKISEDL 150
    GSEKFCVDAN QAGSGSWLKY IRVACSCDDQ NLAMCQINEQ IYYKVIKDIE 200
    PGEELLVHVK EGAYSLGVMA PSLDEDPTFR CDECDELFQC RLDLRRHKKY 250
    ACSSAGAQLY EGLGEELKPE GLGVGSDGQA HECKDCERMF PNKYSLEQHM 300
    IVHTEEREYK CDQCPKAFNW KSNLIRHQMS HDSGKRFECE NCVKVFTDPS 350
    NLQRHIRSQH VGARAHACPD CGKTFATSSG LKQHKHIHST VKPFICEVCH 400
    KSYTQFSNLC RHKRMHADCR TQIKCKDCGQ MFSTTSSLNK HRRFCEGKNH 450
    YTPGSIFTPG LPLTPSPMMD KTKPSPTLNH GGLGFSEYFP SRPHPGSLPF 500
    SAAPPAFPAL TPGFPGIFPP SLYPRPPLLP PTPLLKSPLN HAQDAKLPSP 550
    LGNPALPLVS AVSNSSQGAT AATGSEEKFD GRLEDAYAEK VKNRSPDMSD 600
    GSDFEDINTT TGTDLDTTTG TGSDLDSDLD SDRDKGKDKG KPVESKPEFG 650
    GASVPPGAMN SVAEVPAFYS QHSFFPPPEE QLLTASGAAG DSIKAIASIA 700
    EKYFGPGFMS MQEKKLGSLP YHSVFPFQFL PNFPHSLYPF TDRALAHNLL 750
    VKAEPKSPRD ALKVGGPSAE CPFDLTTKPK EAKPALLAPK VPLIPSSGEE 800
    QPLDLSIGSR ARASQNGGGR EPRKNHVYGE RKPGVSEGLP KVCPAQLPQQ 850
    PSLHYAKPSP FFMDPIYRVE KRKVADPVGV LKEKYLRPSP LLFHPQMSAI 900
    ETMTEKLESF AAMKADSGSS LQPLPHHPFN FRSPPPTLSD PILRKGKERY 950
    TCRYCGKIFP RSANLTRHLR THTGEQPYRC KYCDRSFSIS SNLQRHVRNI 1000
    HNKEKPFKCH LCNRCFGQQT NLDRHLKKHE HEGAPVSQHS GVLTNHLGTS 1050
    ASSPTSESDN HALLDEKEDS YFSEIRNFIA NSEMNQASTR MDKRPEIQDL 1100
    DSNPPCPGSA SAKPEDVEEE EEEELEEEDD DSLAGKSQED TVSPTPEPQG 1150
    VYEDEEDEEP PSLTMGFDHT RRCVEERGGG LLALEPTPTF GKGLDLRRAA 1200
    EEAFEVKDVL NSTLDSEVLK QTLYRQAKNQ AYAMMLSLSE DTPLHAPSQS 1250
    SLDAWLNITG PSSESGAFNP INHL 1274
    Length:1,274
    Mass (Da):140,730
    Last modified:February 5, 2008 - v1
    Checksum:i9039EC0F8EC748BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL611950 Genomic DNA. No translation available.
    AL627123 Genomic DNA. No translation available.
    AL627127 Genomic DNA. No translation available.
    AL627226 Genomic DNA. No translation available.
    RefSeqiNP_001277955.1. NM_001291026.1.
    UniGeneiMm.257785.

    Genome annotation databases

    EnsembliENSMUST00000105637; ENSMUSP00000101262; ENSMUSG00000039410.
    GeneIDi70673.
    UCSCiuc008wbv.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL611950 Genomic DNA. No translation available.
    AL627123 Genomic DNA. No translation available.
    AL627127 Genomic DNA. No translation available.
    AL627226 Genomic DNA. No translation available.
    RefSeqi NP_001277955.1. NM_001291026.1.
    UniGenei Mm.257785.

    3D structure databases

    ProteinModelPortali A2A931.
    SMRi A2A931. Positions 25-209, 279-443, 946-1056.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A2A931.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000105637 ; ENSMUSP00000101262 ; ENSMUSG00000039410 .
    GeneIDi 70673.
    UCSCi uc008wbv.1. mouse.

    Organism-specific databases

    MGIi MGI:1917923. Prdm16.

    Phylogenomic databases

    GeneTreei ENSGT00530000063676.
    HOGENOMi HOG000231144.
    HOVERGENi HBG005619.

    Miscellaneous databases

    ChiTaRSi PRDM16. mouse.
    NextBioi 35542853.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 3.30.160.60. 8 hits.
    InterProi IPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00096. zf-C2H2. 4 hits.
    [Graphical view ]
    SMARTi SM00317. SET. 1 hit.
    SM00355. ZnF_C2H2. 10 hits.
    [Graphical view ]
    PROSITEi PS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2A931_MOUSE
    AccessioniPrimary (citable) accession number: A2A931
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3