ID   A2A929_MOUSE            Unreviewed;       214 AA.
AC   A2A929;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=PR domain containing 16 {ECO:0000313|Ensembl:ENSMUSP00000117598.2};
DE   Flags: Fragment;
GN   Name=Prdm16 {ECO:0000313|Ensembl:ENSMUSP00000117598.2,
GN   ECO:0000313|MGI:MGI:1917923};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000117598.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000117598.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117598.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000117598.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117598.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A2A929; -.
DR   SMR; A2A929; -.
DR   PeptideAtlas; A2A929; -.
DR   ProteomicsDB; 346691; -.
DR   Antibodypedia; 26849; 265 antibodies from 30 providers.
DR   Ensembl; ENSMUST00000124771.2; ENSMUSP00000117598.2; ENSMUSG00000039410.17.
DR   AGR; MGI:1917923; -.
DR   MGI; MGI:1917923; Prdm16.
DR   VEuPathDB; HostDB:ENSMUSG00000039410; -.
DR   GeneTree; ENSGT00940000160951; -.
DR   HOGENOM; CLU_1291596_0_0_1; -.
DR   ChiTaRS; Prdm16; mouse.
DR   Proteomes; UP000000589; Chromosome 4.
DR   Bgee; ENSMUSG00000039410; Expressed in manus and 235 other cell types or tissues.
DR   ExpressionAtlas; A2A929; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0046974; F:histone H3K9 methyltransferase activity; IEA:InterPro.
DR   CDD; cd19213; PR-SET_PRDM16; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR044410; PRDM16_PR-SET.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   Pfam; PF21549; PRDM2_PR; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:A2A929,
KW   ECO:0007829|ProteomicsDB:A2A929};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          82..210
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         214
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000117598.2"
SQ   SEQUENCE   214 AA;  23655 MW;  D533826A2D227E3A CRC64;
     MRSKARARKL AKSDGDVVNN MYEPDPDLLA GQSAEEETED GILSPIPMGP PSPFPTSEDF
     TPKEGSPYEA PVYIPEDIPI PPDFELRESS IPGAGLGIWA KRKMEIGERF GPYVVTPRAA
     LKEADFGWEM LTDTEVSSQE SCIKKISEDL GSEKFCVDAN QAGSGSWLKY IRVACSCDDQ
     NLAMCQINEQ IYYKVIKDIE PGEELLVHVK EGAY
//