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Protein
Submitted name:

PR domain zinc finger protein 16

Gene

Prdm16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • activating transcription factor binding Source: MGI
  • sequence-specific DNA binding Source: MGI
  • SMAD binding Source: MGI

GO - Biological processi

  • negative regulation of granulocyte differentiation Source: MGI
  • negative regulation of transcription, DNA-templated Source: MGI
  • negative regulation of transcription from RNA polymerase II promoter Source: MGI
  • negative regulation of transforming growth factor beta receptor signaling pathway Source: MGI
  • neurogenesis Source: MGI
  • palate development Source: MGI
  • positive regulation of brown fat cell differentiation Source: MGI
  • positive regulation of transcription, DNA-templated Source: MGI
  • somatic stem cell maintenance Source: MGI
  • stem cell maintenance Source: MGI
  • tongue development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PR domain zinc finger protein 16Imported
Gene namesi
Name:Prdm16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1917923. Prdm16.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiA2A929.
ExpressionAtlasiA2A929. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030902.

Structurei

3D structure databases

ProteinModelPortaliA2A929.
SMRiA2A929. Positions 27-212.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000063676.
HOVERGENiHBG031707.

Family and domain databases

InterProiIPR030413. Evi1/Prdm16.
IPR030414. PRDM16.
IPR001214. SET_dom.
[Graphical view]
PANTHERiPTHR24393. PTHR24393. 1 hit.
PTHR24393:SF4. PTHR24393:SF4. 1 hit.
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A2A929-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSKARARKL AKSDGDVVNN MYEPDPDLLA GQSAEEETED GILSPIPMGP
60 70 80 90 100
PSPFPTSEDF TPKEGSPYEA PVYIPEDIPI PPDFELRESS IPGAGLGIWA
110 120 130 140 150
KRKMEIGERF GPYVVTPRAA LKEADFGWEM LTDTEVSSQE SCIKKISEDL
160 170 180 190 200
GSEKFCVDAN QAGSGSWLKY IRVACSCDDQ NLAMCQINEQ IYYKVIKDIE
210
PGEELLVHVK EGAY
Length:214
Mass (Da):23,655
Last modified:February 5, 2008 - v1
Checksum:iD533826A2D227E3A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei214 – 2141Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL611950 Genomic DNA. No translation available.
AL627123 Genomic DNA. No translation available.
AL627127 Genomic DNA. No translation available.
AL627226 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000124771; ENSMUSP00000117598; ENSMUSG00000039410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL611950 Genomic DNA. No translation available.
AL627123 Genomic DNA. No translation available.
AL627127 Genomic DNA. No translation available.
AL627226 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA2A929.
SMRiA2A929. Positions 27-212.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030902.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000124771; ENSMUSP00000117598; ENSMUSG00000039410.

Organism-specific databases

MGIiMGI:1917923. Prdm16.

Phylogenomic databases

GeneTreeiENSGT00530000063676.
HOVERGENiHBG031707.

Miscellaneous databases

ChiTaRSiPrdm16. mouse.
NextBioi35542851.
SOURCEiSearch...

Gene expression databases

BgeeiA2A929.
ExpressionAtlasiA2A929. baseline and differential.

Family and domain databases

InterProiIPR030413. Evi1/Prdm16.
IPR030414. PRDM16.
IPR001214. SET_dom.
[Graphical view]
PANTHERiPTHR24393. PTHR24393. 1 hit.
PTHR24393:SF4. PTHR24393:SF4. 1 hit.
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2A929_MOUSE
AccessioniPrimary (citable) accession number: A2A929
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: June 24, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.