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Protein

CMRF35-like molecule 6

Gene

Cd300c

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionReceptor
Biological processImmunity

Names & Taxonomyi

Protein namesi
Recommended name:
CMRF35-like molecule 6
Short name:
CLM-6
Alternative name(s):
CD300 antigen-like family member C
CD_antigen: CD300c
Gene namesi
Name:Cd300c
Synonyms:Clm6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:3032626 Cd300c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 188ExtracellularSequence analysisAdd BLAST167
Transmembranei189 – 209HelicalSequence analysisAdd BLAST21
Topological domaini210 – 229CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000032012922 – 229CMRF35-like molecule 6Add BLAST208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 110PROSITE-ProRule annotation
Glycosylationi90N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi99N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiA2A7V7
PRIDEiA2A7V7

PTM databases

PhosphoSitePlusiA2A7V7

Expressioni

Gene expression databases

CleanExiMM_CD300C

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052647

Structurei

3D structure databases

ProteinModelPortaliA2A7V7
SMRiA2A7V7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 126Ig-like V-typeAdd BLAST105

Sequence similaritiesi

Belongs to the CD300 family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JCC5 Eukaryota
ENOG4111BBB LUCA
HOGENOMiHOG000231065
HOVERGENiHBG063279
InParanoidiA2A7V7
KOiK06719
PhylomeDBiA2A7V7

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A2A7V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPRVIRLWL PSAVLLSLVP GHFPVRGPST VTGTVGESLS VSCQYEKKLK
60 70 80 90 100
TKKKIWCKWK SNVLCKDIVK TSASEEARNG RVSIRDHPDN LTFTVTLENL
110 120 130 140 150
TLEDAGTYMC MVDIGFFYDA YLQIDKSFKV EVFVVPGKPP FKGSRPGNGI
160 170 180 190 200
NILASPTSSA VHTQPNVTTD DTIPAPSPEL RSLLSSPHFW ILVSLKLPLF
210 220
LSMLGALLWV NRPQRCSGGS SAWPCYENQ
Length:229
Mass (Da):25,336
Last modified:February 20, 2007 - v1
Checksum:i856656FDC5589FD0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti141F → V in AAR27943 (PubMed:14662855).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY457052 mRNA Translation: AAR27943.1
AL607025 Genomic DNA No translation available.
RefSeqiNP_954695.1, NM_199225.1
UniGeneiMm.351450

Genome annotation databases

GeneIDi387565
KEGGimmu:387565
UCSCiuc007mgc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiCLM6_MOUSE
AccessioniPrimary (citable) accession number: A2A7V7
Secondary accession number(s): Q6SJQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health