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Protein

Cerebellar degeneration-related protein 2-like

Gene

Cdr2l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cerebellar degeneration-related protein 2-like
Gene namesi
Name:Cdr2l
Synonyms:Gm21
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2684867. Cdr2l.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 465465Cerebellar degeneration-related protein 2-likePRO_0000307235Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei308 – 3081PhosphoserineCombined sources
Modified residuei318 – 3181PhosphoserineCombined sources
Modified residuei344 – 3441PhosphoserineBy similarity
Modified residuei407 – 4071PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiA2A6T1.
PaxDbiA2A6T1.
PeptideAtlasiA2A6T1.
PRIDEiA2A6T1.

PTM databases

iPTMnetiA2A6T1.
PhosphoSiteiA2A6T1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000050910.
CleanExiMM_CDR2L.
GenevisibleiA2A6T1. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052096.

Structurei

3D structure databases

ProteinModelPortaliA2A6T1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili31 – 6434Sequence analysisAdd
BLAST
Coiled coili91 – 14252Sequence analysisAdd
BLAST
Coiled coili188 – 26679Sequence analysisAdd
BLAST
Coiled coili350 – 37728Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the CDR2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IDY5. Eukaryota.
ENOG410XNUZ. LUCA.
GeneTreeiENSGT00390000018570.
HOVERGENiHBG006695.
InParanoidiA2A6T1.
OMAiYATNEEQ.
OrthoDBiEOG091G071C.
PhylomeDBiA2A6T1.
TreeFamiTF326183.

Family and domain databases

InterProiIPR026079. CDR2.
[Graphical view]
PANTHERiPTHR19232. PTHR19232. 1 hit.

Sequencei

Sequence statusi: Complete.

A2A6T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRAAGMEDY SAEEEESWYD HQDLEQDLHL AAELGKTLLE RNKELEESLQ
60 70 80 90 100
QMYSTNEEQV HEIEYLTKQL DTLRLVNEQH AKVYEQLDLT ARDLELTNQR
110 120 130 140 150
LVMESKAAQQ KIHGLTETIE RLQSQVEELQ AQVEQLRGLE QLRIRREKRE
160 170 180 190 200
RRRTIHTFPC LKELCTSSRC EDAFRLHSSS LELGPRPLEQ ENERLQTLVG
210 220 230 240 250
VLRSQVSQER QRKERAEREY TVVLQEYTEL ERQLCEMEGC RLRVQELEAE
260 270 280 290 300
LLELQQMKQA KTYLLAREEH LAEALLAPLT QAPEADDPQP GSGDDSNAQD
310 320 330 340 350
GVSSPAASPS HAVRKSCSDT ALNAIVAKDP ASRHAGNLTL HANSVRRRGM
360 370 380 390 400
SILREVDEQY HALLEKYEEL LSKCRQHGAG VRHAGVQTSR PISRDSSWRD
410 420 430 440 450
LLGGEESPGE GKAGEKSLSQ HVEAVDKRLE QSQPEYKALF KEIFARIQKT
460
KADINATKVK THSSK
Length:465
Mass (Da):53,213
Last modified:February 20, 2007 - v1
Checksum:iF63244370A51DDA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL603828 Genomic DNA. Translation: CAM13809.1.
CCDSiCCDS36371.1.
RefSeqiNP_001074398.1. NM_001080929.1.
UniGeneiMm.102872.

Genome annotation databases

EnsembliENSMUST00000053288; ENSMUSP00000052096; ENSMUSG00000050910.
GeneIDi237988.
KEGGimmu:237988.
UCSCiuc007mhi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL603828 Genomic DNA. Translation: CAM13809.1.
CCDSiCCDS36371.1.
RefSeqiNP_001074398.1. NM_001080929.1.
UniGeneiMm.102872.

3D structure databases

ProteinModelPortaliA2A6T1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052096.

PTM databases

iPTMnetiA2A6T1.
PhosphoSiteiA2A6T1.

Proteomic databases

MaxQBiA2A6T1.
PaxDbiA2A6T1.
PeptideAtlasiA2A6T1.
PRIDEiA2A6T1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000053288; ENSMUSP00000052096; ENSMUSG00000050910.
GeneIDi237988.
KEGGimmu:237988.
UCSCiuc007mhi.1. mouse.

Organism-specific databases

CTDi30850.
MGIiMGI:2684867. Cdr2l.

Phylogenomic databases

eggNOGiENOG410IDY5. Eukaryota.
ENOG410XNUZ. LUCA.
GeneTreeiENSGT00390000018570.
HOVERGENiHBG006695.
InParanoidiA2A6T1.
OMAiYATNEEQ.
OrthoDBiEOG091G071C.
PhylomeDBiA2A6T1.
TreeFamiTF326183.

Miscellaneous databases

PROiA2A6T1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000050910.
CleanExiMM_CDR2L.
GenevisibleiA2A6T1. MM.

Family and domain databases

InterProiIPR026079. CDR2.
[Graphical view]
PANTHERiPTHR19232. PTHR19232. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCDR2L_MOUSE
AccessioniPrimary (citable) accession number: A2A6T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: February 20, 2007
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.