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A2A6H3 (FBX47_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
F-box only protein 47
Gene names
Name:Fbxo47
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation By similarity.

Subunit structure

Part of a SCF (SKP1-cullin-F-box) protein ligase complex By similarity.

Sequence similarities

Contains 1 F-box domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 451451F-box only protein 47
PRO_0000307726

Regions

Domain41 – 9151F-box

Sequences

Sequence LengthMass (Da)Tools
A2A6H3 [UniParc].

Last modified September 11, 2007. Version 2.
Checksum: 4DD1A55803102DE6

FASTA45151,374
        10         20         30         40         50         60 
MASRVNTSFT LIPKQKCRRS NHHSSYFCNT LDSDPQLLST LGNFKVLPLE ILHIILRYLS 

        70         80         90        100        110        120 
VKDIGMLSMV SKTVSQHIIN YISTSSGSRR LLLQNFHDLD LPGTKEETAL LEHYRALGLL 

       130        140        150        160        170        180 
FKRCTLLLPT KERLKYIHKI LSEVSCFKFS GCSVPLQCLG LSCYGMFLQT LTAGWDELEC 

       190        200        210        220        230        240 
HRVYNFLCEL TNLSRKMQTV VCNKPGSARK LELRVRLFCR NVLLDHWTHR SDSAFWLTRI 

       250        260        270        280        290        300 
LKPWPMVNQA RLLYIIFGPT SPHDGQVIWQ EMIEGPTDES SLKGLANAIK LLYDTGAKGW 

       310        320        330        340        350        360 
TADDVISLVD ELSVVPREWL LENNARLLIL SGNNICFTFM ASKAVNGRAV ELARLVVFLA 

       370        380        390        400        410        420 
LVCEKELYCM DWTVRMMQKV CKVFSTAAER KSFLQSIANA FACVTMEMLQ PVMSGDRDDD 

       430        440        450 
DRGFLNLFHL LHAQANFHKE VLYLTMNAIS S 

« Hide

References

[1]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL596446 Genomic DNA. Translation: CAM22785.2.
BC158049 mRNA. Translation: AAI58050.1.
CCDSCCDS36299.1.
RefSeqNP_001074904.1. NM_001081435.1.
XP_006534391.1. XM_006534328.1.
XP_006534392.1. XM_006534329.1.
XP_006534393.1. XM_006534330.1.
XP_006534394.1. XM_006534331.1.
UniGeneMm.245939.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000091471.

PTM databases

PhosphoSiteA2A6H3.

Proteomic databases

PRIDEA2A6H3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000093939; ENSMUSP00000091471; ENSMUSG00000070336.
GeneID72973.
KEGGmmu:72973.
UCSCuc007lfb.1. mouse.

Organism-specific databases

CTD494188.
MGIMGI:1920223. Fbxo47.

Phylogenomic databases

eggNOGNOG70508.
GeneTreeENSGT00390000014175.
HOGENOMHOG000261636.
HOVERGENHBG051584.
InParanoidB2RY07.
KOK10321.
OMAFTLIPNQ.
OrthoDBEOG7M98GB.
PhylomeDBA2A6H3.
TreeFamTF343134.

Gene expression databases

BgeeA2A6H3.
CleanExMM_FBXO47.
GenevestigatorA2A6H3.

Family and domain databases

InterProIPR001810. F-box_dom.
[Graphical view]
PfamPF00646. F-box. 1 hit.
[Graphical view]
SUPFAMSSF81383. SSF81383. 1 hit.
PROSITEPS50181. FBOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio337257.
PROA2A6H3.
SOURCESearch...

Entry information

Entry nameFBX47_MOUSE
AccessionPrimary (citable) accession number: A2A6H3
Secondary accession number(s): B2RY07
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: September 11, 2007
Last modified: July 9, 2014
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot