Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SH3 domain-binding protein 1

Gene

Sh3bp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SH3 domain-binding protein 1Imported
Gene namesi
Name:Sh3bp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:104603. Sh3bp1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA2A5V3.
PRIDEiA2A5V3.

PTM databases

iPTMnetiA2A5V3.

Expressioni

Gene expression databases

BgeeiA2A5V3.
ExpressionAtlasiA2A5V3. baseline and differential.
GenevisibleiA2A5V3. MM.

Interactioni

Protein-protein interaction databases

IntActiA2A5V3. 1 interaction.
STRINGi10090.ENSMUSP00000052181.

Structurei

3D structure databases

ProteinModelPortaliA2A5V3.
SMRiA2A5V3. Positions 216-471.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 262246BARInterPro annotationAdd
BLAST
Domaini276 – 469194Rho-GAPInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili181 – 21232Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains BAR domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4270. Eukaryota.
ENOG410XRR2. LUCA.
GeneTreeiENSGT00760000118863.
HOGENOMiHOG000179193.
HOVERGENiHBG000015.
TreeFamiTF316514.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR004148. BAR_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF03114. BAR. 1 hit.
PF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00721. BAR. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS51021. BAR. 1 hit.
PS50238. RHOGAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2A5V3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKRQLHRMR QLAHTGSSGR TPETAEFLGE DLLQVEQRLE PAKRAAHNVH
60 70 80 90 100
KRLQACLQGQ SGADMDKRVK KLPLMALSTT MAESFKELDP DSSMGKALEM
110 120 130 140 150
TCAIQNQLAR ILAEFEMTLE RDVLQPLSRL SEEELPAILK HKKSLQKLVS
160 170 180 190 200
DWNTLKSRLS QAAKNSGSNQ GLGGASGSHT HTTTANKVEM LKEEEEELKK
210 220 230 240 250
KVEQCKDEYL ADLYHFSTKE DSYANYFIHL LEIQADYHRK SLTSLDTALA
260 270 280 290 300
ELRDNHSQAD HSPLTTAAPF SRVYGVSLRT HLQDLGRDIA LPIEACVLLL
310 320 330 340 350
LSEGMQEEGL FRLAAGASVL KRLKQTMASD PHSLEEFCSD PHAVAGALKS
360 370 380 390 400
YLRELPEPLM TSDLYDDWMR AASLKEPGAR LEALHDVCSR LPQENFNNLR
410 420 430 440 450
YLMKFLALLA EEQDVNKMTP SNIAIVLGPN LLWPPEKEGD QAQLDAASVS
460 470 480 490 500
SIQVVGVVEA LIQNADTLFP GDINFNVSGI FPGLAPQEKV SSQQVSEELP
510 520 530 540 550
PVTVPAPATT PAPTPAPASM AVRERTEADL PKPTSPKVSR NPTETAASAE
560 570 580
DMTRSQGSYQ KEEQTCLFLE DFYFFSLANV FL
Length:582
Mass (Da):64,463
Last modified:February 20, 2007 - v1
Checksum:i60DD185B6A8FDB96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592169 Genomic DNA. No translation available.
RefSeqiNP_033190.2. NM_009164.3.
UniGeneiMm.4462.

Genome annotation databases

EnsembliENSMUST00000061239; ENSMUSP00000052181; ENSMUSG00000022436.
GeneIDi20401.
UCSCiuc007wro.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592169 Genomic DNA. No translation available.
RefSeqiNP_033190.2. NM_009164.3.
UniGeneiMm.4462.

3D structure databases

ProteinModelPortaliA2A5V3.
SMRiA2A5V3. Positions 216-471.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA2A5V3. 1 interaction.
STRINGi10090.ENSMUSP00000052181.

PTM databases

iPTMnetiA2A5V3.

Proteomic databases

PaxDbiA2A5V3.
PRIDEiA2A5V3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000061239; ENSMUSP00000052181; ENSMUSG00000022436.
GeneIDi20401.
UCSCiuc007wro.1. mouse.

Organism-specific databases

CTDi23616.
MGIiMGI:104603. Sh3bp1.

Phylogenomic databases

eggNOGiKOG4270. Eukaryota.
ENOG410XRR2. LUCA.
GeneTreeiENSGT00760000118863.
HOGENOMiHOG000179193.
HOVERGENiHBG000015.
TreeFamiTF316514.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiA2A5V3.
ExpressionAtlasiA2A5V3. baseline and differential.
GenevisibleiA2A5V3. MM.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR004148. BAR_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF03114. BAR. 1 hit.
PF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00721. BAR. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS51021. BAR. 1 hit.
PS50238. RHOGAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2A5V3_MOUSE
AccessioniPrimary (citable) accession number: A2A5V3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: June 8, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.