<?xml version='1.0' encoding='UTF-8'?>
<uniprot xmlns="http://uniprot.org/uniprot" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/support/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2007-02-20" modified="2013-04-03" version="43">
<accession>A2A5D9</accession>
<name>A2A5D9_MOUSE</name>
<protein>
<submittedName>
<fullName evidence="2">Orexin</fullName>
</submittedName>
</protein>
<gene>
<name type="primary" evidence="2 3">Hcrt</name>
</gene>
<organism evidence="2">
<name type="scientific">Mus musculus</name>
<name type="common">Mouse</name>
<dbReference type="NCBI Taxonomy" id="10090"/>
<lineage>
<taxon>Eukaryota</taxon>
<taxon>Metazoa</taxon>
<taxon>Chordata</taxon>
<taxon>Craniata</taxon>
<taxon>Vertebrata</taxon>
<taxon>Euteleostomi</taxon>
<taxon>Mammalia</taxon>
<taxon>Eutheria</taxon>
<taxon>Euarchontoglires</taxon>
<taxon>Glires</taxon>
<taxon>Rodentia</taxon>
<taxon>Sciurognathi</taxon>
<taxon>Muroidea</taxon>
<taxon>Muridae</taxon>
<taxon>Murinae</taxon>
<taxon>Mus</taxon>
<taxon>Mus</taxon>
</lineage>
</organism>
<reference key="1" evidence="2">
<citation type="journal article" date="2009" name="PLoS Biol." volume="7" first="E1000112" last="E1000112">
<title>Lineage-specific biology revealed by a finished genome assembly of the mouse.</title>
<authorList>
<person name="Church D.M."/>
<person name="Goodstadt L."/>
<person name="Hillier L.W."/>
<person name="Zody M.C."/>
<person name="Goldstein S."/>
<person name="She X."/>
<person name="Bult C.J."/>
<person name="Agarwala R."/>
<person name="Cherry J.L."/>
<person name="DiCuccio M."/>
<person name="Hlavina W."/>
<person name="Kapustin Y."/>
<person name="Meric P."/>
<person name="Maglott D."/>
<person name="Birtle Z."/>
<person name="Marques A.C."/>
<person name="Graves T."/>
<person name="Zhou S."/>
<person name="Teague B."/>
<person name="Potamousis K."/>
<person name="Churas C."/>
<person name="Place M."/>
<person name="Herschleb J."/>
<person name="Runnheim R."/>
<person name="Forrest D."/>
<person name="Amos-Landgraf J."/>
<person name="Schwartz D.C."/>
<person name="Cheng Z."/>
<person name="Lindblad-Toh K."/>
<person name="Eichler E.E."/>
<person name="Ponting C.P."/>
</authorList>
<dbReference type="PubMed" id="19468303"/>
<dbReference type="DOI" id="10.1371/journal.pbio.1000112"/>
</citation>
<scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
<source>
<strain evidence="2">C57BL/6J</strain>
</source>
</reference>
<reference key="2" evidence="2">
<citation type="submission" date="2012-02" db="UniProtKB">
<authorList>
<consortium name="Ensembl"/>
</authorList>
</citation>
<scope>IDENTIFICATION</scope>
<source>
<strain evidence="2">C57BL/6J</strain>
</source>
</reference>
<comment type="caution">
<text evidence="2">The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.</text>
</comment>
<dbReference type="EMBL" id="AL591466">
<property type="status" value="NOT_ANNOTATED_CDS"/>
<property type="molecule type" value="Genomic_DNA"/>
</dbReference>
<dbReference type="IPI" id="IPI00649446"/>
<dbReference type="ProteinModelPortal" id="A2A5D9"/>
<dbReference type="SMR" id="A2A5D9">
<property type="residue range" value="33-65"/>
</dbReference>
<dbReference type="Ensembl" id="ENSMUST00000107360">
<property type="protein sequence ID" value="ENSMUSP00000102983"/>
<property type="gene ID" value="ENSMUSG00000045471"/>
</dbReference>
<dbReference type="MGI" id="MGI:1202306">
<property type="gene designation" value="Hcrt"/>
</dbReference>
<dbReference type="GeneTree" id="ENSGT00390000014272"/>
<dbReference type="HOGENOM" id="HOG000230990"/>
<dbReference type="HOVERGEN" id="HBG000256"/>
<dbReference type="NextBio" id="35542578"/>
<dbReference type="ArrayExpress" id="A2A5D9"/>
<dbReference type="GO" id="GO:0048471">
<property type="term" value="C:perinuclear region of cytoplasm"/>
<property type="evidence" value="IDA:MGI"/>
</dbReference>
<dbReference type="GO" id="GO:0007631">
<property type="term" value="P:feeding behavior"/>
<property type="evidence" value="IEA:InterPro"/>
</dbReference>
<dbReference type="GO" id="GO:0007218">
<property type="term" value="P:neuropeptide signaling pathway"/>
<property type="evidence" value="IEA:InterPro"/>
</dbReference>
<dbReference type="InterPro" id="IPR001704">
<property type="entry name" value="Orexin"/>
</dbReference>
<dbReference type="PANTHER" id="PTHR15173">
<property type="entry name" value="PTHR15173"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="Pfam" id="PF02072">
<property type="entry name" value="Orexin"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="PRINTS" id="PR01091">
<property type="entry name" value="OREXINPP"/>
</dbReference>
<proteinExistence type="evidence at transcript level"/>
<keyword id="KW-0181" evidence="1">Complete proteome</keyword>
<keyword id="KW-1185" evidence="1">Reference proteome</keyword>
<evidence key="1" type="ECO:0000203"/>
<evidence key="2" type="ECO:0000313">
<source>
<dbReference type="Ensembl" id="ENSMUSP00000102983"/>
</source>
</evidence>
<evidence key="3" type="ECO:0000313">
<source>
<dbReference type="MGI" id="MGI:1202306"/>
</source>
</evidence>
<sequence length="106" mass="11441" checksum="86A29ECA7A1870AB" modified="2007-02-20" version="1">
MNFPSTKVPWAAVTLLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAA
GILTLGKRRPGPPGLQGRLQRLLQANGTYTERSNTRAQSPPGKGWM
</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
</copyright>
</uniprot>