A2A5D4 (A2A5D4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Signal transducer and activator of transcription 5A Ensembl ENSMUSP00000117204

Gene names

Name:

Stat5a Ensembl ENSMUSP00000117204 MGI 103036

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000117204

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	51 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000117204

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	JAK-STAT cascade Inferred from direct assay PubMed 10485657. Source: MGI Peyer's patch development Inferred from genetic interaction PubMed 15294943. Source: MGI T cell differentiation in thymus Inferred from genetic interaction PubMed 15294943. Source: MGI T cell homeostasis Inferred from genetic interaction PubMed 10072077. Source: MGI cytokine-mediated signaling pathway Inferred from direct assay PubMed 10485657. Source: MGI development of secondary female sexual characteristics Inferred from mutant phenotype PubMed 9630227. Source: MGI development of secondary male sexual characteristics Inferred from mutant phenotype PubMed 9630227. Source: MGI epithelial cell differentiation involved in prostate gland development Inferred from mutant phenotype PubMed 10908145. Source: MGI female pregnancy Inferred from genetic interaction PubMed 15471942. Source: MGI lactation Inferred from mutant phenotype PubMed 11706048PubMed 9630227. Source: MGI lipid storage Inferred from genetic interaction PubMed 9630227. Source: MGI luteinization Inferred from genetic interaction PubMed 9630227. Source: MGI mammary gland epithelium development Inferred from mutant phenotype PubMed 12040017. Source: MGI natural killer cell differentiation Inferred from genetic interaction PubMed 10072077. Source: MGI negative regulation of erythrocyte differentiation Inferred from genetic interaction PubMed 10072077. Source: MGI negative regulation of mast cell apoptotic process Inferred from mutant phenotype PubMed 15947484. Source: MGI peptidyl-tyrosine phosphorylation Inferred from direct assay PubMed 12388746. Source: MGI positive regulation of B cell differentiation Inferred from genetic interaction PubMed 10979977. Source: MGI positive regulation of activated T cell proliferation Inferred from direct assay PubMed 10072077. Source: MGI positive regulation of gamma-delta T cell differentiation Inferred from genetic interaction PubMed 15294943. Source: MGI positive regulation of inflammatory response Inferred from genetic interaction PubMed 10652277. Source: MGI positive regulation of interleukin-2 biosynthetic process Inferred from genetic interaction PubMed 10072077. Source: MGI positive regulation of mast cell differentiation Inferred from mutant phenotype PubMed 15947484. Source: MGI positive regulation of mast cell proliferation Inferred from mutant phenotype PubMed 15947484. Source: MGI positive regulation of mitotic cell cycle Inferred from genetic interaction PubMed 10072077. Source: MGI positive regulation of multicellular organism growth Inferred from genetic interaction PubMed 9630227. Source: MGI positive regulation of natural killer cell differentiation Inferred from mutant phenotype PubMed 9841920. Source: MGI positive regulation of natural killer cell mediated cytotoxicity Inferred from mutant phenotype PubMed 9841920. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay PubMed 19666510. Source: MGI prostate gland epithelium morphogenesis Inferred from mutant phenotype PubMed 10908145. Source: MGI regulation of cell adhesion Inferred from mutant phenotype PubMed 11706048. Source: MGI regulation of epithelial cell differentiation Inferred from mutant phenotype PubMed 11706048. Source: MGI regulation of steroid metabolic process Inferred from genetic interaction PubMed 15471942. Source: MGI response to peptide hormone stimulus Inferred from direct assay PubMed 12388746. Source: MGI
Cellular_component	cytoplasm Inferred from direct assay PubMed 11254359PubMed 14522949. Source: MGI nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA polymerase II core promoter sequence-specific DNA binding Inferred from direct assay PubMed 19666510. Source: MGI sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro signal transducer activity Inferred from genetic interaction PubMed 10485657. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	51	1	Ensembl ENSMUSP00000117204

Sequences

	Sequence		Length	Mass (Da)
	A2A5D4 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 6C85153B36ADF503	FASTA	51	6,007
	10 20 30 40 50 MAGWIQAQQL QGDALRQMQV LYGQHFPIEV RHYLAQWIES QPWDAIDLDN P

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000117204.
[2]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000117204.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591466 Genomic DNA. No translation available.
IPI	IPI00649213.
UniGene	Mm.277403.
3D structure databases
ProteinModelPortal	A2A5D4.
SMR	A2A5D4. Positions 2-50.
ModBase	Search...
Proteomic databases
PaxDb	A2A5D4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000133036; ENSMUSP00000117204; ENSMUSG00000004043.
Organism-specific databases
MGI	MGI:103036. Stat5a.
Phylogenomic databases
eggNOG	NOG245085.
GeneTree	ENSGT00550000074337.
InParanoid	A2A5D4.
Gene expression databases
ArrayExpress	A2A5D4.
Family and domain databases
Gene3D	1.10.532.10. 1 hit.
InterPro	IPR001217. STAT_TF_core. IPR013799. STAT_TF_prot_interaction. [Graphical view]
PANTHER	PTHR11801. PTHR11801. 1 hit.
Pfam	PF02865. STAT_int. 1 hit. [Graphical view]
SUPFAM	SSF48092. STAT. 1 hit.
ProtoNet	Search...
Other
NextBio	35542576.
SOURCE	Search...

Entry information

Entry name

A2A5D4_MOUSE

Accession

Primary (citable) accession number: A2A5D4

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	April 3, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)