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A2A5C2 (A2A5C2_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length480 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ETS family. RuleBase RU004019

Contains 1 ETS DNA-binding domain. RuleBase RU004019

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000102794

Ontologies

Keywords
   Cellular componentNucleus RuleBase RU004018
   LigandDNA-binding RuleBase RU004018
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processbranching involved in mammary gland duct morphogenesis

Inferred from mutant phenotype PubMed 18977342. Source: MGI

motor neuron axon guidance

Inferred from mutant phenotype PubMed 12372283. Source: MGI

negative regulation of mammary gland epithelial cell proliferation

Inferred from mutant phenotype PubMed 18977342. Source: MGI

positive regulation of transcription, DNA-templated

Inferred from direct assay PubMed 15466854. Source: MGI

regulation of branching involved in mammary gland duct morphogenesis

Inferred from direct assay PubMed 12871699. Source: MGI

regulation of transcription from RNA polymerase II promoter

Inferred from Biological aspect of Ancestor. Source: RefGenome

stem cell differentiation

Inferred from mutant phenotype PubMed 18977342. Source: MGI

transcription from RNA polymerase II promoter

Inferred from Biological aspect of Ancestor. Source: GOC

   Cellular_componentintracellular

Inferred from direct assay PubMed 10482234. Source: MGI

nucleus

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Molecular_functionDNA binding

Inferred from direct assay PubMed 12527199. Source: MGI

sequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding RNA polymerase II transcription factor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A2A5C2 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 7B10D83B54CBC839

FASTA48053,485
        10         20         30         40         50         60 
MERRMKGGYL DQRVPYTFCS KSPGNGSLGE ALMVPQGKLM DPGSLPPSDS EDLFQDLSHF 

        70         80         90        100        110        120 
QETWLAEAQV PDSDEQFVPD FHSENLAFHS PTTRIKKEPQ SPRTDPALSC SRKPPLPYHH 

       130        140        150        160        170        180 
GEQCLYSRQI AIKSPAPGAP GQSPLQPFSR AEQQQSLLRA SSSSQSHPGH GYLGEHSSVF 

       190        200        210        220        230        240 
QQPVDMCHSF TSPQGGGREP LPAPYQHQLS EPCPPYPQQN FKQEYHDPLY EQAGQPASSQ 

       250        260        270        280        290        300 
GGVSGHRYPG AGVVIKQERT DFAYDSDVPG CASMYLHPEG FSGPSPGDGV MGYGYEKSLR 

       310        320        330        340        350        360 
PFPDDVCIVP EKFEGDIKQE GIGAFREGPP YQRRGALQLW QFLVALLDDP TNAHFIAWTG 

       370        380        390        400        410        420 
RGMEFKLIEP EEVARLWGIQ KNRPAMNYDK LSRSLRYYYE KGIMQKVAGE RYVYKFVCEP 

       430        440        450        460        470        480 
EALFSLAFPD NQRPALKAEF DRPVSEEDTV PLSHLDESPA YLPELTGPAP PFGHRGGYSY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591436 Genomic DNA. No translation available.
RefSeqXP_006532528.1. XM_006532465.1.
UniGeneMm.5025.

3D structure databases

ProteinModelPortalA2A5C2.
SMRA2A5C2. Positions 334-430.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000107176; ENSMUSP00000102794; ENSMUSG00000017724.
GeneID18612.
KEGGmmu:18612.
UCSCuc007lpu.1. mouse.

Organism-specific databases

CTD2118.
MGIMGI:99423. Etv4.

Phylogenomic databases

GeneTreeENSGT00750000117517.
HOVERGENHBG000231.
KOK15592.
OrthoDBEOG7K9K2M.

Gene expression databases

ArrayExpressA2A5C2.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR000418. Ets_dom.
IPR006715. ETS_PEA3_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00178. Ets. 1 hit.
PF04621. ETS_PEA3_N. 1 hit.
[Graphical view]
PRINTSPR00454. ETSDOMAIN.
SMARTSM00413. ETS. 1 hit.
[Graphical view]
PROSITEPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSETV4. mouse.
NextBio35542572.
SOURCESearch...

Entry information

Entry nameA2A5C2_MOUSE
AccessionPrimary (citable) accession number: A2A5C2
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: July 9, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)