Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A2A5C2

- A2A5C2_MOUSE

UniProt

A2A5C2 - A2A5C2_MOUSE

Protein
Submitted name:

ETS translocation variant 4

Gene

Etv4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. sequence-specific DNA binding Source: InterPro
    3. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: RefGenome

    GO - Biological processi

    1. branching involved in mammary gland duct morphogenesis Source: MGI
    2. motor neuron axon guidance Source: MGI
    3. negative regulation of mammary gland epithelial cell proliferation Source: MGI
    4. positive regulation of transcription, DNA-templated Source: MGI
    5. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    6. regulation of branching involved in mammary gland duct morphogenesis Source: MGI
    7. regulation of transcription from RNA polymerase II promoter Source: RefGenome
    8. stem cell differentiation Source: MGI
    9. transcription from RNA polymerase II promoter Source: GOC

    Keywords - Ligandi

    DNA-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ETS translocation variant 4Imported
    Gene namesi
    Name:Etv4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:99423. Etv4.

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: MGI
    2. nucleus Source: RefGenome

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Expressioni

    Gene expression databases

    ArrayExpressiA2A5C2.

    Structurei

    3D structure databases

    ProteinModelPortaliA2A5C2.
    SMRiA2A5C2. Positions 334-430.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ETS family.UniRule annotation
    Contains 1 ETS DNA-binding domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117517.
    HOVERGENiHBG000231.
    KOiK15592.
    OrthoDBiEOG7K9K2M.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR000418. Ets_dom.
    IPR006715. ETS_PEA3_N.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00178. Ets. 1 hit.
    PF04621. ETS_PEA3_N. 1 hit.
    [Graphical view]
    PRINTSiPR00454. ETSDOMAIN.
    SMARTiSM00413. ETS. 1 hit.
    [Graphical view]
    PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
    PS00346. ETS_DOMAIN_2. 1 hit.
    PS50061. ETS_DOMAIN_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2A5C2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERRMKGGYL DQRVPYTFCS KSPGNGSLGE ALMVPQGKLM DPGSLPPSDS    50
    EDLFQDLSHF QETWLAEAQV PDSDEQFVPD FHSENLAFHS PTTRIKKEPQ 100
    SPRTDPALSC SRKPPLPYHH GEQCLYSRQI AIKSPAPGAP GQSPLQPFSR 150
    AEQQQSLLRA SSSSQSHPGH GYLGEHSSVF QQPVDMCHSF TSPQGGGREP 200
    LPAPYQHQLS EPCPPYPQQN FKQEYHDPLY EQAGQPASSQ GGVSGHRYPG 250
    AGVVIKQERT DFAYDSDVPG CASMYLHPEG FSGPSPGDGV MGYGYEKSLR 300
    PFPDDVCIVP EKFEGDIKQE GIGAFREGPP YQRRGALQLW QFLVALLDDP 350
    TNAHFIAWTG RGMEFKLIEP EEVARLWGIQ KNRPAMNYDK LSRSLRYYYE 400
    KGIMQKVAGE RYVYKFVCEP EALFSLAFPD NQRPALKAEF DRPVSEEDTV 450
    PLSHLDESPA YLPELTGPAP PFGHRGGYSY 480
    Length:480
    Mass (Da):53,485
    Last modified:February 20, 2007 - v1
    Checksum:i7B10D83B54CBC839
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL591436 Genomic DNA. No translation available.
    RefSeqiXP_006532528.1. XM_006532465.1.
    UniGeneiMm.5025.

    Genome annotation databases

    EnsembliENSMUST00000107176; ENSMUSP00000102794; ENSMUSG00000017724.
    GeneIDi18612.
    KEGGimmu:18612.
    UCSCiuc007lpu.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL591436 Genomic DNA. No translation available.
    RefSeqi XP_006532528.1. XM_006532465.1.
    UniGenei Mm.5025.

    3D structure databases

    ProteinModelPortali A2A5C2.
    SMRi A2A5C2. Positions 334-430.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000107176 ; ENSMUSP00000102794 ; ENSMUSG00000017724 .
    GeneIDi 18612.
    KEGGi mmu:18612.
    UCSCi uc007lpu.1. mouse.

    Organism-specific databases

    CTDi 2118.
    MGIi MGI:99423. Etv4.

    Phylogenomic databases

    GeneTreei ENSGT00750000117517.
    HOVERGENi HBG000231.
    KOi K15592.
    OrthoDBi EOG7K9K2M.

    Miscellaneous databases

    ChiTaRSi ETV4. mouse.
    NextBioi 35542572.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi A2A5C2.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR000418. Ets_dom.
    IPR006715. ETS_PEA3_N.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00178. Ets. 1 hit.
    PF04621. ETS_PEA3_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00454. ETSDOMAIN.
    SMARTi SM00413. ETS. 1 hit.
    [Graphical view ]
    PROSITEi PS00345. ETS_DOMAIN_1. 1 hit.
    PS00346. ETS_DOMAIN_2. 1 hit.
    PS50061. ETS_DOMAIN_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiA2A5C2_MOUSE
    AccessioniPrimary (citable) accession number: A2A5C2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3