A2A4H2 (A2A4H2_MOUSE) Unreviewed, UniProtKB/TrEMBL
Last modified
November 16, 2011.
Version 43.
History...
Names and origin
| Protein names | Submitted name: ATP citrate lyase EMBL CAM23025.1 Submitted name: ATP citrate lyase, isoform CRA_b EMBL EDL02556.1 | ||||
| Gene names |
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| Organism | Mus musculus (Mouse) EMBL CAM23025.1 | ||||
| Taxonomic identifier | 10090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus |
Protein attributes
| Sequence length | 1091 AA. |
| Sequence status | Complete. |
| Protein existence | Predicted |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Lyase EMBL CAM23025.1 |
| Gene Ontology (GO) | |
| Biological process | acetyl-CoA biosynthetic process Traceable author statement. Source: MGI cellular carbohydrate metabolic processInferred from electronic annotation. Source: InterPro |
| Cellular component | mitochondrion Inferred from direct assay. Source: MGI |
| Molecular function | ATP binding Inferred from electronic annotation. Source: InterPro ATP citrate synthase activityTraceable author statement. Source: MGI lyase activityInferred from electronic annotation. Source: UniProtKB-KW succinate-CoA ligase (ADP-forming) activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
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References
| [1] | "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. Stephenson L.D.Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL02556.1. |
| [2] | Pearce A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [3] | Matthews L. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [4] | Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL02556.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AL590968, BX842667 Genomic DNA. Translation: CAM23025.1. BX842667, AL590968 Genomic DNA. Translation: CAM27799.1. CH466662 Genomic DNA. Translation: EDL02556.1. |
| IPI | IPI00762047. |
| RefSeq | NP_598798.1. NM_134037.3. |
| UniGene | Mm.282039. |
3D structure databases | |
| ProteinModelPortal | A2A4H2. |
| SMR | A2A4H2. Positions 2-425, 477-810, 866-1075. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A2A4H2. |
Proteomic databases | |
| PRIDE | A2A4H2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 104112. |
| KEGG | mmu:104112. |
| UCSC | uc007lll.2. mouse. |
Organism-specific databases | |
| CTD | 47. |
| MGI | MGI:103251. Acly. |
Phylogenomic databases | |
| eggNOG | roNOG07311. |
| HOVERGEN | HBG003318. |
| PhylomeDB | A2A4H2. |
Gene expression databases | |
| Bgee | A2A4H2. |
| Genevestigator | A2A4H2. |
Family and domain databases | |
| InterPro | IPR014608. ATP-citrate_synthase. IPR013650. ATP-grasp_succ-CoA_synth-type. IPR013816. ATP_grasp_subdomain_2. IPR017440. Cit_synth/succinyl-CoA_lig_AS. IPR016142. Citrate_synth-like_lrg_a-sub. IPR016143. Citrate_synth-like_sm_a-sub. IPR002020. Citrate_synthase-like. IPR016141. Citrate_synthase-like_core. IPR003781. CoA-bd. IPR005810. CoA_lig_alpha. IPR005811. CoA_ligase. IPR016040. NAD(P)-bd_dom. IPR017866. Succ-CoA_synthase_bsu_CS. IPR016102. Succinyl-CoA_synth-like. [Graphical view] |
| Gene3D | G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:1.10.580.10. Citrate_synthase_lrg_a-sub. 1 hit. G3DSA:1.10.230.10. Citrate_synthase_sm_a-sub. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:3.40.50.261. Succinyl-CoA_synth-like. 2 hits. |
| KO | K01648. |
| Pfam | PF08442. ATP-grasp_2. 1 hit. PF00285. Citrate_synt. 1 hit. PF02629. CoA_binding. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view] |
| PIRSF | PIRSF036511. ATP_citrt_syn. 1 hit. |
| SUPFAM | SSF48256. Citrate_synthase_core. 1 hit. SSF52210. CoA_ligase. 1 hit. |
| PROSITE | PS01216. SUCCINYL_COA_LIG_1. 1 hit. PS00399. SUCCINYL_COA_LIG_2. 1 hit. PS01217. SUCCINYL_COA_LIG_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 356548. |
| SOURCE | Search... |
Entry information
| Entry name | A2A4H2_MOUSE | ||||||||
| Accession | Primary (citable) accession number: A2A4H2 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
