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Protein

Solute carrier family 25 member 43

Gene

Slc25a43

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 43
Gene namesi
Name:Slc25a43
Synonyms:Gm8
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2684854. Slc25a43.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei68 – 8821Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei110 – 13021Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei166 – 18621Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei205 – 22521Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei262 – 28221Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: UniProtKB-SubCell
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 341341Solute carrier family 25 member 43PRO_0000291824Add
BLAST

Proteomic databases

PaxDbiA2A3V2.
PRIDEiA2A3V2.

PTM databases

iPTMnetiA2A3V2.
PhosphoSiteiA2A3V2.

Expressioni

Gene expression databases

BgeeiA2A3V2.
CleanExiMM_SLC25A43.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035392.

Structurei

3D structure databases

ProteinModelPortaliA2A3V2.
SMRiA2A3V2. Positions 16-295.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati11 – 10191Solcar 1Add
BLAST
Repeati105 – 18581Solcar 2Add
BLAST
Repeati200 – 29899Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
GeneTreeiENSGT00830000128432.
HOGENOMiHOG000007857.
HOVERGENiHBG108441.
InParanoidiA2A3V2.
KOiK15120.
OMAiCFRQTVK.
OrthoDBiEOG741Z34.
TreeFamiTF354298.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2A3V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATWRRDGRL TGSQRLLCAG LAGAFSLSLT APLELATVLA QVGKVQSHSL
60 70 80 90 100
GLWATGRRVW LSEGPRALWK GNGVACLRLF PCSMVQLAAY RKFVVLFMDD
110 120 130 140 150
LGRISQWSSI VTGSLAGMVS TIVTYPTDLI KTRLMVQNVL EPSYRGLIHA
160 170 180 190 200
FSTIYQQEGF LALYRGVSLT VLGAVPFSAG SLLVYMNLEK VWNGPRDRFS
210 220 230 240 250
HLQNFANVCV AAAVSQTLSF PFDTVKRKMQ AQSPYLPHYG GVDVHFSGAA
260 270 280 290 300
DCFRQIVKTQ GVLGLWNGLT ANLLKVVPYF GVMFSMFEFC KRIFLYQNGY
310 320 330 340
TLSPLTYKLT PGVDQSLKPQ ELRELKKFFK RRKLHSKTPP W
Length:341
Mass (Da):38,064
Last modified:February 20, 2007 - v1
Checksum:iFA60DED0FAD3439F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450397 Genomic DNA. Translation: CAM13293.1.
BC147709 mRNA. Translation: AAI47710.1.
BC147717 mRNA. Translation: AAI47718.1.
CCDSiCCDS40925.1.
RefSeqiNP_001078966.1. NM_001085497.2.
UniGeneiMm.336014.

Genome annotation databases

EnsembliENSMUST00000047655; ENSMUSP00000035392; ENSMUSG00000037636.
GeneIDi194744.
KEGGimmu:194744.
UCSCiuc009sxr.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450397 Genomic DNA. Translation: CAM13293.1.
BC147709 mRNA. Translation: AAI47710.1.
BC147717 mRNA. Translation: AAI47718.1.
CCDSiCCDS40925.1.
RefSeqiNP_001078966.1. NM_001085497.2.
UniGeneiMm.336014.

3D structure databases

ProteinModelPortaliA2A3V2.
SMRiA2A3V2. Positions 16-295.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035392.

PTM databases

iPTMnetiA2A3V2.
PhosphoSiteiA2A3V2.

Proteomic databases

PaxDbiA2A3V2.
PRIDEiA2A3V2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047655; ENSMUSP00000035392; ENSMUSG00000037636.
GeneIDi194744.
KEGGimmu:194744.
UCSCiuc009sxr.2. mouse.

Organism-specific databases

CTDi203427.
MGIiMGI:2684854. Slc25a43.

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
GeneTreeiENSGT00830000128432.
HOGENOMiHOG000007857.
HOVERGENiHBG108441.
InParanoidiA2A3V2.
KOiK15120.
OMAiCFRQTVK.
OrthoDBiEOG741Z34.
TreeFamiTF354298.

Miscellaneous databases

PROiA2A3V2.
SOURCEiSearch...

Gene expression databases

BgeeiA2A3V2.
CleanExiMM_SLC25A43.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiS2543_MOUSE
AccessioniPrimary (citable) accession number: A2A3V2
Secondary accession number(s): B2RWC0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 20, 2007
Last modified: July 6, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.