Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Muscleblind-like 2 (Drosophila), isoform CRA_a

Gene

MBNL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri13 – 41C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri47 – 73C3H1-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri176 – 204C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri212 – 238C3H1-typePROSITE-ProRule annotationAdd BLAST27

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Muscleblind-like 2 (Drosophila), isoform CRA_aImported
Submitted name:
cDNA FLJ76890, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNAImported
Submitted name:
cDNA, FLJ79493, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNAImported
Gene namesi
Name:MBNL2Imported
ORF Names:hCG_27557Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134901420.

Expressioni

Gene expression databases

BgeeiENSG00000139793.
ExpressionAtlasiA2A3S3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000267287.

Structurei

3D structure databases

ProteinModelPortaliA2A3S3.
SMRiA2A3S3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 41C3H1-typeInterPro annotationAdd BLAST29
Domaini47 – 73C3H1-typeInterPro annotationAdd BLAST27
Domaini176 – 204C3H1-typeInterPro annotationAdd BLAST29
Domaini212 – 238C3H1-typeInterPro annotationAdd BLAST27

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri13 – 41C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri47 – 73C3H1-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri176 – 204C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri212 – 238C3H1-typePROSITE-ProRule annotationAdd BLAST27

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2494. Eukaryota.
ENOG410ZNRC. LUCA.
HOGENOMiHOG000230928.
HOVERGENiHBG006999.

Family and domain databases

InterProiView protein in InterPro
IPR000571. Znf_CCCH.
PfamiView protein in Pfam
PF00642. zf-CCCH. 2 hits.
SMARTiView protein in SMART
SM00356. ZnF_C3H1. 4 hits.
PROSITEiView protein in PROSITE
PS50103. ZF_C3H1. 4 hits.

Sequencei

Sequence statusi: Complete.

A2A3S3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNVAPVRD TKWLTLEVCR QFQRGTCSRS DEECKFAHPP KSCQVENGRV
60 70 80 90 100
IACFDSLKGR CSRENCKYLH PPTHLKTQLE INGRNNLIQQ KTAAAMLAQQ
110 120 130 140 150
MQFMFPGTPL HPVPTFPVGP AIGTNTAISF APYLAPVTPG VGLVPTEILP
160 170 180 190 200
TTPVIVPGSP PVTVPGSTAT QKLLRTDKLE VCREFQRGNC ARGETDCRFA
210 220 230 240 250
HPADSTMIDT SDNTVTVCMD YIKGRCMREK CKYFHPPAHL QAKIKAAQHQ
260 270 280 290 300
ANQAAVAAQA AAAAATVMAF PPGALHPLPK RQALEKSNGT SAVFNPSVLH
310 320 330 340 350
YQQALTSAQL QQHAAFIPTD NSEIISRNGM ECQESALRIT KHCYCTYYPV
360
SSSIELPQTA C
Length:361
Mass (Da):39,356
Last modified:February 5, 2008 - v1
Checksum:i72253C4F7EDF5447
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291727 mRNA. Translation: BAF84416.1.
AK315844 mRNA. Translation: BAF98735.1.
CH471085 Genomic DNA. Translation: EAX08968.1.
RefSeqiNP_997187.1. NM_207304.2.
XP_016875800.1. XM_017020311.1.
UniGeneiHs.657347.

Genome annotation databases

GeneIDi10150.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291727 mRNA. Translation: BAF84416.1.
AK315844 mRNA. Translation: BAF98735.1.
CH471085 Genomic DNA. Translation: EAX08968.1.
RefSeqiNP_997187.1. NM_207304.2.
XP_016875800.1. XM_017020311.1.
UniGeneiHs.657347.

3D structure databases

ProteinModelPortaliA2A3S3.
SMRiA2A3S3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000267287.

Protocols and materials databases

DNASUi10150.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10150.

Organism-specific databases

CTDi10150.
PharmGKBiPA134901420.

Phylogenomic databases

eggNOGiKOG2494. Eukaryota.
ENOG410ZNRC. LUCA.
HOGENOMiHOG000230928.
HOVERGENiHBG006999.

Miscellaneous databases

ChiTaRSiMBNL2. human.
GenomeRNAii10150.

Gene expression databases

BgeeiENSG00000139793.
ExpressionAtlasiA2A3S3. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR000571. Znf_CCCH.
PfamiView protein in Pfam
PF00642. zf-CCCH. 2 hits.
SMARTiView protein in SMART
SM00356. ZnF_C3H1. 4 hits.
PROSITEiView protein in PROSITE
PS50103. ZF_C3H1. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA2A3S3_HUMAN
AccessioniPrimary (citable) accession number: A2A3S3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 12, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.